The Vanderbilt Institute of Chemical Biology presents Dr. Ned Porter, Vanderbilt University: "Oxysterols and a Human Syndrome: An Accidental Tour into Cholesterol Biosynthesis"
Key Lecture Points:
· Inborn errors in post-lanosterol sterol biosynthesis
· 7-Dehydrocholesterol, Smith-Lemli-Opitz syndrome
· Mechanisms of sterol free radical peroxidation
· Oxysterol reactivity and metabolism in cells and rodents
· Diels-Alder and Ene-chemistry based assays of cell culture and human plasmas