vanderbilt medical center

Obtaining Probes

Please send your inquiries to Julie L. Engers or Craig W. Lindsley.

ML252 - KCNQ2 Inhibitor
  Vanderbilt Identification Number:
IC50/EC50:  
Anti-target and Selectivity:  
Chemical Probe (PubChem SID):  
Pubchem Summary BioAssay ID:  
Commercial Source & Catalog number: unavailable
   
ML228 - HIF Activator
Vanderbilt Identification Number: VU0418946
IC50/EC50:  
Anti-target and Selectivity:  
Chemical Probe (PubChem SID): 111978103
Pubchem Summary BioAssay ID: 1971
Commercial Source & Catalog number: unavailable
   
ML218 - Cav3 T-type Inhibitor
Vanderbilt Identification Number: VU0413807
IC50/EC50: 150nM
Anti-target and Selectivity:  
Chemical Probe (PubChem SID): 92310249
Pubchem Summary BioAssay ID: 493023
Commercial Source & Catalog number: unavailable
   
ML213 - KCNQ2 Activator
Vanderbilt Identification Number: VU0448090
IC50/EC50:  
Anti-target and Selectivity:  
Chemical Probe (PubChem SID): 104223736
Pubchem Summary BioAssay ID: 2258
Commercial Source & Catalog number: unavailable
   
ML204 - TRPC4 Inhibitor
Vanderbilt Identification Number: VU0024172
IC50/EC50:  
Anti-target and Selectivity:  
Chemical Probe (PubChem SID): 103061324
Pubchem Summary BioAssay ID: 2256
Commercial Source & Catalog number: unavailable
   
ML182 - mGluR4 PAM Second Generation
Vanderbilt Identification Number: VU0400195
IC50/EC50: mGluRs 1, 2, 3, 5, 7, 8 [>50]
Anti-target and Selectivity:  
Chemical Probe (PubChem SID): 99309089
Pubchem Summary BioAssay ID: 2434
Commercial Source & Catalog number: unavailable
   
ML173 - M4 PAM Second Generation
Vanderbilt Identification Number: VU0359508
IC50/EC50:  
Anti-target and Selectivity: M1, M2, M3, M5 [>30]
Chemical Probe (PubChem SID): 87352032
Pubchem Summary BioAssay ID: 2416
Commercial Source & Catalog number: unavailable
   
ML172 - M5 PAM Second Generation
Vanderbilt Identification Number: VU0400265
IC50/EC50: 1918 nM
Anti-target and Selectivity: M1, M2, M3, M4 [>30]
Chemical Probe (PubChem SID): 87352032
Pubchem Summary BioAssay ID: 2416
Commercial Source & Catalog number: unavailable
   
ML169 - M1 PAM Second Generation
Vanderbilt Identification Number: VU0405652
IC50/EC50: 1380 nM
Anti-target and Selectivity: M2, M3, M4, M5 [>30]
Chemical Probe (PubChem SID): 85756541
Pubchem Summary BioAssay ID: 2543
Commercial Source & Catalog number: unavailable
   
ML137 - M1 PAM
Vanderbilt Identification Number: VU0366369
IC50/EC50: 830 nM
Anti-target and Selectivity: M2, M3, M4, M5 [>30]
Chemical Probe (PubChem SID): 85286053
Pubchem Summary BioAssay ID: 2543
Commercial Source & Catalog number unavailable
   
ML133 - Kir2.1 Inhibitor
Vanderbilt Identification Number: VU0404943
IC50/EC50: 284 nM
Anti-target and Selectivity: ROMK [100]
Chemical Probe (PubChem SID): 87457855
Pubchem Summary BioAssay ID: 1843
Commercial Source & Catalog number unavailable
   
ML129 - M5 PAM
Vanderbilt Identification Number: VU0238429
IC50/EC50: 1100 nM
Anti-target and Selectivity: M1, M2, M3, M4 [>30]
Chemical Probe (PubChem SID): 85285486
Pubchem Summary BioAssay ID: 2416
Commercial Source & Catalog number Tocris Bioscience: 3634
   
ML128 - mGluR4 PAM
Vanderbilt Identification Number: VU0361737
IC50/EC50: 240 nM
Anti-target and Selectivity: mGluRs 1, 2, 3, 5, 7, 8 [>50]
Chemical Probe (PubChem SID): 85240643
Pubchem Summary BioAssay ID: 2437
Commercial Source & Catalog number Tocris Bioscience: 3707
   
ML112 - ROMK Inhibitor
Vanderbilt Identification Number: VU0365318
IC50/EC50: 220 nM
Anti-target and Selectivity: Kir2.1, Kir4.1, Kir7.1, Kir2.3 [>50]
Chemical Probe (PubChem SID): 84975340
Pubchem Summary BioAssay ID: 1918
Commercial Source & Catalog number unavailable
   
ML111- ROMK & Kir7.1 Inhibitor
Vanderbilt Identification Number: VU0277590
IC50/EC50: 294 nM
Anti-target and Selectivity: Kir2.1 and Kir4.1 [>30]
Chemical Probe (PubChem SID): 84975334
Pubchem Summary BioAssay ID: 1918
Commercial Source & Catalog number Sigma-Aldrich: V4265
  Tocris Bioscience: 3891
ML108 - M4 PAM
Vanderbilt Identification Number: VU0152100
IC50/EC50: 370 nM
Anti-target and Selectivity: M1, M2, M3, M5 [>100}
Chemical Probe (PubChem SID): 85163688
Pubchem Summary BioAssay ID: 626
Commercial Source & Catalog number Tocris Bioscience: 3141
   
ML077 - KCC2 Antagonist
Vanderbilt Identification Number: VU0255011
IC50/EC50: 537 nM
Anti-target and Selectivity: NKCC1 [>100- fold]
Chemical Probe (PubChem SID): 56405461
Pubchem Summary BioAssay ID: 1799
Commercial Source & Catalog number Sigma-Aldrich: V3890
  Tocris Bioscience: 3888
ML071 - M1 Allosteric Agonist
Vanderbilt Identification Number: VU0357017
IC50/EC50: 198 nM
Anti-target and Selectivity: M2-M5 [>263- fold]
Chemical Probe (PubChem SID): 56353039
Pubchem Summary BioAssay ID: 1798
Commercial Source & Catalog number Sigma-Aldrich: V3265
  Tocris Bioscience: 4295