vanderbilt medical center

Probe Reports

Title
Grant Number
ML#
Discovery of a Small Molecule Activator of the Hypoxia Inducible Factor Pathway
MH082355-01A2
ML228
Inhibitors for the Menin-Mixed Lineage (MLL) Interaction MH084875-01A1 ML227
Scaffold Hoppings Afford a Highly Selective in vitro and in vivo Calcium T-Type Inhibitor Free from IP Issues
NS050771-01
ML218
A small molecule activator of KCNQ2 and KCNQ4 channels DA027716-01
ML213
Novel Chemical Inhibitor of TRPC4 Channels NS056942-01
ML204
Discovery of non-covalent inhibitors of the SARS main proteinase 3CLpro MH084162-01A1 ML188
Discovery of a potent, selective and orally active in vivo mGlu4 positive allosteric modulator NS053536-01 ML182
Discovery of a Highly Selective in vitro and in vivo M4 Positive Allosteric Modulator (PAM) Series with Greatly Improved Human Receptor Activity MH077606-01
ML173
Development of the First Highly Selective mAChR 5 (M5) Positive Allosteric Modulator (PAM) MH077606-01 ML172
Discovery and development of a second highly selective M1 Positive Allosteric Modulator (PAM). MH077606-01
ML169
Discovery and development of the a highly selective M1 Positive Allosteric Modulator (PAM) MH077606-01 ML137
A potent and selective small molecule Kir2.1 inhibitor DA026212-01 ML133
Discovery of the first mAChR 5 (M5) selective ligand, an M5 Positive Allosteric Modulator (PAM) MH077606-01 ML129
Discovery of a potent, selective and in vivo active mGluR4 positive allosteric modulator (PAM) NS053536-01 ML128
Discovery of a Small Molecule Inhibitor of ROMK with unprecedented selectivity NS057041-01 ML112
Discovery of a Small Molecule Inhibitor of ROMK and Kir7.1 NS057041-01 ML111
Discovery of a Highly Selective in vitro and in vivo M4 Positive Allosteric Modulator (PAM) MH077606-01
ML108
Discovery of a Highly Selective KCC2 Antagonist NS053658-01 ML077
Discovery of a Highly Selective in vitro and in vivo M1 Allosteric Agonist Probe MH077606-01 ML071

 

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