High Throughput Screening of Ligands of TRP Channels

VU Chemistry Team Leader:  Corey Hopkins

Michael Zhu

Ohio State University

HTS for Small Molecule Modulators of EB Virus Protein: Protein Interactions

VU Chemistry Team Leader:  Kyle Emmitte

Theodore Jardetzky

Northwestern University

Discovery of Novel Allosteric Modulators of the M1 Muscarinic Receptor: Agonist Primary Screen

VU Chemistry Team Leader: Craig Lindsley

P. Jeffrey Conn

Vanderbilt University Medical Center

Discovery of Novel Allosteric Agonists of the M4 Muscarinic Receptor: Primary Screen

VU Chemistry Team Leader: Craig Lindsley

Colleen Niswender

Vanderbilt University Medical Center

HTS Assay for Cav3 T-type Channels Using FLIPR

VU Chemistry Team Leader: Craig Lindsley

Xinmin Simon Xie

A direct assay for HTS of Gi/Go-linked GPCRs: mGluR8 as the prototype

VU Chemistry Team Leader: Craig Lindsley

Colleen Niswender

Vanderbilt University Medical Center

Identification of Novel Modulators of ROMK K+ channel activity

VU Chemistry Team Leader: Brian Chauder

Jerod Denton

Vanderbilt University Medical Center

Identification of Novel Modulators of Cl-dependent Transport Processes via HTS

VU Chemistry Team Leader: Craig Lindsley

Delpire Eric

Vanderbilt University Medical Center

Identification of compounds that protect HERG from block by proarrhythmic agents

VU Chemistry Team Leader:  Corey Hopkins

Sabina Kupershmidt

Vanderbilt University Medical Center

TR-FRET HTS Assay for Inhibitors of MEKK2-MEK5 PB1 Domain Interaction

VU Chemistry Team Leader: Craig Lindsley

Kazuhiro Nakamura

University of North Carolina, Chapel Hill

Small Molecule Modulators for Redox Regulation in the Mitochondrial Intermembrane

VU Chemistry Team Leader:  Corey Hopkins

Carla Koehler

University of California Los Angeles

Identification of Molecular Probes to Activate Hypoxia Inducible Factor Pathways

VU Chemistry Team Leader:  Kyle Emmitte

Shawn Gilbert

University of Alabama at Birmingham

HTS Screen for Small Molecule Inhibitors of the Mint-PDZ Domain

VU Chemistry Team Leader:  Kyle Emmitte

Ilya Bezprozvanny

University of Texas SW Medical Center

Screening for Inhibitors Targeting the Menin-MLL Interaction in MLL Related Leukemia

VU Chemistry Team Leader:  Shaun Stauffer

Cierpicki Tomasz & Jolanta Grembecka

University of Virginia Charlottesville

High Throughput Screening for Identifying Lead Compounds Against 3CLpro

VU Chemistry Team Leader:  Shaun Stauffer

Valerie Tokars

University of Illinois at Chicago

The High Throughput Screening for Developing T Cell Immune Modulators

VU Chemistry Team Leader:  Corey Hopkins

Inkyu Hwang

Scripps Research Institute

Allosteric Potentiators of the oxytocin system for the control of social motivation

VU Chemistry Team Leader: Brian Chauder

Michael Jarstfer

University of North Carolina at Chapel Hill

Screening for Inhibitors of MLL Translocation Proteins in Leukemia

VU Chemistry Team Leader: Shaun Stauffer

John Bushweller

University of Virginia, Charlottesville

Development of Chemical Probes for KCNQ Potassium Channels

VU Chemistry Team Leader: Corey Hopkins

Min Li

John Hopkins Ion Channel Center