» Chen, J, Chen, JK, Falck, JR, Anjaiah, S, Capdevila, JH, Harris, RC Mitogenic activity and signaling mechanism of 2-(14,15- epoxyeicosatrienoyl)glycerol, a novel cytochrome p450 arachidonate metabolite Mol Cell Biol 2007. 27:3023-34

» Cheng, H, Wang, S, Jo, YI, Hao, CM, Zhang, M, Fan, X, Kennedy, C, Breyer, MD, Moeckel, GW, Harris, RC Overexpression of cyclooxygenase-2 predisposes to podocyte injury J Am Soc Nephrol 2007. 18:551-9

» Chen, X, Abair, TD, Ibanez, MR, Su, Y, Frey, MR, Dise, RS, Polk, DB, Singh, AB, Harris, RC, Zent, R, Pozzi, A Integrin {alpha}1{beta}1 Controls Reactive Oxygen Species Synthesis by Negatively Regulating Epidermal Growth Factor Receptor-Mediated Rac Activation Mol Cell Biol 2007. 27:3313-26

» Breyer, MD, Tchekneva, E, Qi, Z, Takahashi, T, Fogo, AB, Zhao, HJ, Harris, RC Genetics of diabetic nephropathy: lessons from mice Semin Nephrol 2007. 27:237-47

» Kanetsuna, Y, Takahashi, K, Nagata, M, Gannon, MA, Breyer, MD, Harris, RC, Takahashi, T Deficiency of endothelial nitric-oxide synthase confers susceptibility to diabetic nephropathy in nephropathy-resistant inbred mice Am J Pathol 2007. 170:1473-84

» Yao, B, Xu, J, Qi, Z, Harris, RC, Zhang, MZ Role of renal cortical cyclooxygenase-2 expression in hyperfiltration in rats with high-protein intake Am J Physiol Renal Physiol 2006. 291:F368-74

» Kanetsuna, Y, Hirano, K, Nagata, M, Gannon, MA, Takahashi, K, Harris, RC, Breyer, MD, Takahashi, T Characterization of diabetic nephropathy in a transgenic model of hypoinsulinemic diabetes Am J Physiol Renal Physiol 2006. 291:F1315-22

» Chen, J, Chen, JK, Neilson, EG, Harris, RC Role of EGF receptor activation in angiotensin II-induced renal epithelial cell hypertrophy J Am Soc Nephrol 2006. 17:1615-23

» Harris, RC, Neilson, EG Toward a unified theory of renal progression Annu Rev Med 2006. 57:365-80

» Harris, RC COX-2 and the kidney J Cardiovasc Pharmacol 2006. 47 Suppl 1:S37-42

» Cheng, H, Harris, RC Potential side effects of renin inhibitors--mechanisms based on comparison with other renin-angiotensin blockers Expert Opin Drug Saf 2006. 5:631-41

» Zhao, HJ, Wang, S, Cheng, H, Zhang, MZ, Takahashi, T, Fogo, AB, Breyer, MD, Harris, RC Endothelial nitric oxide synthase deficiency produces accelerated nephropathy in diabetic mice J Am Soc Nephrol 2006. 17:2664-9

» Zhang, MZ, Yao, B, Cheng, HF, Wang, SW, Inagami, T, Harris, RC Renal cortical cyclooxygenase 2 expression is differentially regulated by angiotensin II AT(1) and AT(2) receptors Proc Natl Acad Sci U S A 2006. 103:16045-50

» Breyer, MD, B??ttinger, E, Brosius, FC, Coffman, TM, Harris, RC, Heilig, CW, Sharma, K, , Mouse models of diabetic nephropathy J Am Soc Nephrol 2005. 16:27-45

» Rao, R, Zhang, MZ, Zhao, M, Cai, H, Harris, RC, Breyer, MD, Hao, CM Lithium treatment inhibits renal GSK-3 activity and promotes cyclooxygenase 2-dependent polyuria Am J Physiol Renal Physiol 2005. 288:F642-9

» Zhang, MZ, Yao, B, McKanna, JA, Harris, RC Cross talk between the intrarenal dopaminergic and cyclooxygenase-2 systems Am J Physiol Renal Physiol 2005. 288:F840-5

» Yao, B, Harris, RC, Zhang, MZ Interactions between 11beta-hydroxysteroid dehydrogenase and COX-2 in kidney Am J Physiol Regul Integr Comp Physiol 2005. 288:R1767-73

» Chen, JK, Chen, J, Neilson, EG, Harris, RC Role of mammalian target of rapamycin signaling in compensatory renal hypertrophy J Am Soc Nephrol 2005. 16:1384-91

» Breyer, MD, B??ttinger, E, Brosius, FC, Coffman, TM, Fogo, A, Harris, RC, Heilig, CW, Sharma, K Diabetic nephropathy: of mice and men Adv Chronic Kidney Dis 2005. 12:128-45

» Cheng, HF, Harris, RC Renal effects of non-steroidal anti-inflammatory drugs and selective cyclooxygenase-2 inhibitors Curr Pharm Des 2005. 11:1795-804

» Singh, AB, Harris, RC Autocrine, paracrine and juxtacrine signaling by EGFR ligands Cell Signal 2005. 17:1183-93

» Cheng, H, Zhang, M, Moeckel, GW, Zhao, Y, Wang, S, Qi, Z, Breyer, MD, Harris, RC Expression of mediators of renal injury in the remnant kidney of ROP mice is attenuated by cyclooxygenase-2 inhibition Nephron Exp Nephrol 2005. 101:e75-85

» Cheng, HF, Zhang, MZ, Harris, RC NITRIC OXIDE STIMULATES CYCLOOXYGENASE-2 IN CULTURED CTAL CELLS THROUGH A P38-DEPENDENT PATHWAY Am J Physiol Renal Physiol 2005. :

» Shivakumar, BR, Wang, Z, Hammond, TG, Harris, RC EP24.15 interacts with the angiotensin II type I receptor and bradykinin B2 receptor Cell Biochem Funct 2004. 23:195-204

» Singh, AB, Harris, RC Epidermal growth factor receptor activation differentially regulates claudin expression and enhances transepithelial resistance in Madin-Darby canine kidney cells J Biol Chem 2004. 279:3543-52

» Qi, Z, Whitt, I, Mehta, A, Jin, J, Zhao, M, Harris, RC, Fogo, AB, Breyer, MD Serial determination of glomerular filtration rate in conscious mice using FITC-inulin clearance Am J Physiol Renal Physiol 2004. 286:F590-6

» Cheng, HF, Harris, RC Cyclooxygenases, the kidney, and hypertension Hypertension 2004. 43:525-30

» Zhang, MZ, Mai, W, Li, C, Cho, SY, Hao, C, Moeckel, G, Zhao, R, Kim, I, Wang, J, Xiong, H, Wang, H, Sato, Y, Wu, Y, Nakanuma, Y, Lilova, M, Pei, Y, Harris, RC, Li, S, Coffey, RJ, Sun, L, Wu, D, Chen, XZ, Breyer, MD, Zhao, ZJ, McKanna, JA, Wu, G PKHD1 protein encoded by the gene for autosomal recessive polycystic kidney disease associates with basal bodies and primary cilia in renal epithelial cells Proc Natl Acad Sci U S A 2004. 101:2311-6

» Singh, AB, Tsukada, T, Zent, R, Harris, RC Membrane-associated HB-EGF modulates HGF-induced cellular responses in MDCK cells J Cell Sci 2004. 117:1365-79

» Zhang, MZ, Sanchez Lopez, P, McKanna, JA, Harris, RC Regulation of cyclooxygenase expression by vasopressin in rat renal medulla Endocrinology 2004. 145:1402-9

» Fisher, ME, Rossini, M, Simmons, E, Harris, RC, Moeckel, G, Zent, R A woman with chronic hepatitis C infection and nephrotic syndrome who developed multiple renal lesions after interferon alfa therapy Am J Kidney Dis 2004. 44:567-73

» Harris, RC, Zhang, MZ, Cheng, HF Cyclooxygenase-2 and the renal renin-angiotensin system Acta Physiol Scand 2004. 181:543-7

» Chen, X, Moeckel, G, Morrow, JD, Cosgrove, D, Harris, RC, Fogo, AB, Zent, R, Pozzi, A Lack of integrin alpha1beta1 leads to severe glomerulosclerosis after glomerular injury Am J Pathol 2004. 165:617-30

» Chen, D, Roberts, R, Pohl, M, Nigam, S, Kreidberg, J, Wang, Z, Heino, J, Ivaska, J, Coffa, S, Harris, RC, Pozzi, A, Zent, R Differential expression of collagen- and laminin-binding integrins mediates ureteric bud and inner medullary collecting duct cell tubulogenesis Am J Physiol Renal Physiol 2004. 287:F602-11

» Harris, RC Interactions between COX-2 and the renin-angiotensin system in the kidney Acta Physiol Scand 2003. 177:423-7

» Harris, RC, Chung, E, Coffey, RJ EGF receptor ligands Exp Cell Res 2003. 284:2-13

» Zhang, MZ, Wang, SW, Cheng, H, Zhang, Y, McKanna, JA, Harris, RC Regulation of renal cortical cyclooxygenase-2 in young rats Am J Physiol Renal Physiol 2003. 285:F881-8

» Wang, Z, Chen, JK, Wang, SW, Moeckel, G, Harris, RC Importance of functional EGF receptors in recovery from acute nephrotoxic injury J Am Soc Nephrol 2003. 14:3147-54

» Cheng, HF, Harris, RC Does cyclooxygenase-2 affect blood pressure Curr Hypertens Rep 2003. 5:87-92

» Means, AL, Ray, KC, Singh, AB, Washington, MK, Whitehead, RH, Harris, RC, Wright, CV, Coffey, RJ, Leach, SD Overexpression of heparin-binding EGF-like growth factor in mouse pancreas results in fibrosis and epithelial metaplasia Gastroenterology 2003. 124:1020-36

» Cheng, H-F., Wang, J-L., Zhang, M-Z, McKanna, J.A. and Harris, R.C. Extracellular Chloride Regulates Renal Cortical Cyclooxygenase-2 (COX-2) Expression: Role of p38. Journal of Clinical Investigation. In Press

» Zhang, MZ, Hao, CM, Breyer, MD, Harris, RC, McKanna, JA Mineralocorticoid regulation of cyclooxygenase-2 expression in rat renal medulla Am J Physiol Renal Physiol 2002. 283:F509-16

» Cheng, HF, Wang, SW, Zhang, MZ, McKanna, JA, Breyer, R, Harris, RC Prostaglandins that increase renin production in response to ACE inhibition are not derived from cyclooxygenase-1 Am J Physiol Regul Integr Comp Physiol 2002. 283:R638-46

» Cheng, HF, Harris, RC Cyclooxygenase-2 expression in cultured cortical thick ascending limb of Henle increases in response to decreased extracellular ionic content by both transcriptional and post-transcriptional mechanisms. Role of p38-mediated pathways J Biol Chem 2002. 277:45638-43

» Harris, RC Cyclooxygenase-2 and the kidney: functional and pathophysiological implications J Hypertens Suppl 2002. 20:S3-9

» Harris, RC Cyclooxygenase-2 inhibition and renal physiology Am J Cardiol 2002. 89:10D-17D

» Burleigh, ME, Babaev, VR, Oates, JA, Harris, RC, Gautam, S, Riendeau, D, Marnett, LJ, Morrow, JD, Fazio, S, Linton, MF Cyclooxygenase-2 promotes early atherosclerotic lesion formation in LDL receptor-deficient mice Circulation 2002. 105:1816-23

» Chen, JK, Capdevila, J, Harris, RC Heparin-binding EGF-like growth factor mediates the biological effects of P450 arachidonate epoxygenase metabolites in epithelial cells Proc Natl Acad Sci U S A 2002. 99:6029-34

» Capdevila, JH, Harris, RC, Falck, JR Microsomal cytochrome P450 and eicosanoid metabolism Cell Mol Life Sci 2002. 59:780-9

» Cheng, HF, Wang, CJ, Moeckel, GW, Zhang, MZ, McKanna, JA, Harris, RC Cyclooxygenase-2 inhibitor blocks expression of mediators of renal injury in a model of diabetes and hypertension Kidney Int 2002. 62:929-39

» Sakai, M. Tsukada, T. and Harris, R.C Induction of HB-EGF expression by reactive oxygen species: role of AP-1-mediated transcriptional activation Experimental Nephrology 2001. 9:28-30

» Takemura, T., Hino, S., Kuwajima, H., Yanagida, H, Okada, M., Nagata, M, Sasaki, S., Barasch, J., Harris, R.C. and Yoshioka, K Induction of collecting duct morphogenesis in vitro by heparin-binding EGF-like growth factor J.A.S.N. 2001. 12:964-972

» Cheng, H-F., Wang, J-L., Zhang, M-Z, Wang, S-W, McKanna, J.A. and Harris, R. C Genetic deletion of cyclooxygenase-2 prevents increased renin expression in response to ACE inhibition Am. J. Physiol. 2001. 280:F449-F456

» Chen, J-K, Zimpelmann, J., Harris, R.C. and Burns, K.D Angiotensin IV induces tyrosine phosphorylation of focal adhesion kinase and paxillin in proximal tubule cells Am. J. Physiol. 2001. 280:F980-988

» Chen, J-K, Capdevila, J.C. and Harris, R.C A novel role for cP450 expoxygenase to inhibit apoptosis in renal epithelial cells Mol. Cell Biol. 2001. 21:6322-6331

» Chen, JK, Capdevila, J, Harris, RC Cytochrome p450 epoxygenase metabolism of arachidonic acid inhibits apoptosis Mol Cell Biol 2001. 21:6322-31

» Harris, RC, Breyer, MD Physiological regulation of cyclooxygenase-2 in the kidney Am J Physiol Renal Physiol 2001. 281:F1-11

» Cheng, HF, Wang, JL, Zhang, MZ, Wang, SW, McKanna, JA, Harris, RC Genetic deletion of COX-2 prevents increased renin expression in response to ACE inhibition Am J Physiol Renal Physiol 2001. 280:F449-56

» Breyer, MD, Harris, RC Cyclooxygenase 2 and the kidney Curr Opin Nephrol Hypertens 2001. 10:89-98

» Cheng, H-F., Wang, J-L., Zhang, M-Z, McKanna, J.A. and Harris, R.C Regulation of macula densa cyclooxygenase-2 expression by neuronal nitric oxide synthase Am. J. Physiol 2000. 279:F122-9

» Wang, J-L., Cheng, H-F., Sheppel, S. and Harris, R.C The cyclooxygenase-2 inhibitor, SC58326, decreasesproteinuria and retards progression of glomerulosclerosis in the rat remnant kidney Kidney Int 2000. 57:2334-42

» Chen, J-K, Capdevila, J.C. and Harris, R.C Overexpression of C-Terminal Src Kinase (CSK) Blocks 14,15-Epoxyeicosatrienoic Acid-Induced Tyrosine Phosphorylation and Mitogenesis J. Biol. Chem. 2000. 275:13789-13792

» Cheng, HF, Wang, JL, Zhang, MZ, McKanna, JA, Harris, RC Role of p38 in the regulation of renal cortical cyclooxygenase-2 expression by extracellular chloride J Clin Invest 2000. 106:681-8

» Cheng, HF, Wang, JL, Zhang, MZ, McKanna, JA, Harris, RC Nitric oxide regulates renal cortical cyclooxygenase-2 expression Am J Physiol Renal Physiol 2000. 279:F122-9

» K??mhoff, M, Wang, JL, Cheng, HF, Langenbach, R, McKanna, JA, Harris, RC, Breyer, MD Cyclooxygenase-2-selective inhibitors impair glomerulogenesis and renal cortical development Kidney Int 2000. 57:414-22

» Harris, RC Cyclooxygenase-2 in the kidney J Am Soc Nephrol 2000. 11:2387-94

» Chen, JK, Capdevila, J, Harris, RC Overexpression of C-terminal Src kinase blocks 14, 15-epoxyeicosatrienoic acid-induced tyrosine phosphorylation and mitogenesis J Biol Chem 2000. 275:13789-92

» Harris, RC, Cheng, H, Wang, J, Zhang, M, McKanna, JA Interactions of the renin-angiotensin system and neuronal nitric oxide synthase in regulation of cyclooxygenase-2 in the macula densa Acta Physiol Scand 2000. 168:47-51

» Haralson, MA, DiMari, SJ, Hoover, RL, Harris, RC Effects of epidermal growth factor on collagen expression by rat kidney mesangial cells in culture Matrix Biol 2000. 19:47-59

» Capdevila, JH, Falck, JR, Harris, RC Cytochrome P450 and arachidonic acid bioactivation. Molecular and functional properties of the arachidonate monooxygenase J Lipid Res 2000. 41:163-81

» Wang, JL, Cheng, HF, Shappell, S, Harris, RC A selective cyclooxygenase-2 inhibitor decreases proteinuria and retards progressive renal injury in rats Kidney Int 2000. 57:2334-42

» Zhang, M-Z, Harris, R.C and McKanna, J.A Modulation of expression of cyclooxygenase-2 in rat kidney by endogenous glucocorticoids and mineralocorticoids Proc. Natl. Acad. Sci. USA 1999. 96:15280-15285

» Wang, J-L., Cheng, H-F. and Harris, R.C Cyclooxygenase-2 inhibition decreases renin content and lowers blood pressure in a model of renovascular hypertension Hypertension 1999. 34:96-191

» Cheng, H-F, Wang, J-F, Zhang, M-Z, McKanna, J.A. and Harris, R.C Angiotensin II attenuates renal cortical cyclooxygenase-2 expression J. Clin. Invest. 1999. 103:953-961

» Chen, J-K, Falck, Wang, D-W J.R., Capdevila, J.C. and Harris, R.C Transfection of an active cP450 arachidonic acid epoxygenase indicates that 14,15-epoxyeicosatrienoic acid functions as a second messenger in response to epidermal growth factor J. Biol. Chem 1999. 274:4764-4769

» Wang, JL, Cheng, HF, Harris, RC Cyclooxygenase-2 inhibition decreases renin content and lowers blood pressure in a model of renovascular hypertension Hypertension 1999. 34:96-101

» Cheng, HF, Wang, JL, Zhang, MZ, Miyazaki, Y, Ichikawa, I, McKanna, JA, Harris, RC Angiotensin II attenuates renal cortical cyclooxygenase-2 expression J Clin Invest 1999. 103:953-61

» Zhang, MZ, Harris, RC, McKanna, JA Regulation of cyclooxygenase-2 (COX-2) in rat renal cortex by adrenal glucocorticoids and mineralocorticoids Proc Natl Acad Sci U S A 1999. 96:15280-5

» Harris, RC Potential mechanisms and physiologic actions of intracellular angiotensin II Am J Med Sci 1999. 318:374-9

» Gibbs, SR, Goins, RA, Belvin, EL, Dimari, SJ, Merriam, AP, Bowling-Brown, S, Harris, RC, Haralson, MA Characterization of the collagen phenotype of rabbit proximal tubule cells in culture Connect Tissue Res 1999. 40:173-88

» Takemura, T, Hino, S, Murata, Y, Yanagida, H, Okada, M, Yoshioka, K, Harris, RC Coexpression of CD9 augments the ability of membrane-bound heparin-binding epidermal growth factor-like growth factor (proHB-EGF) to preserve renal epithelial cell viability Kidney Int 1999. 55:71-81

» Chen, JK, Wang, DW, Falck, JR, Capdevila, J, Harris, RC Transfection of an active cytochrome P450 arachidonic acid epoxygenase indicates that 14,15-epoxyeicosatrienoic acid functions as an intracellular second messenger in response to epidermal growth factor J Biol Chem 1999. 274:4764-9

» Becker, BN, Kondo, S, Chen, JK, Harris, RC Tyrosine kinase inhibition affects type 1 angiotensin II receptor internalization J Recept Signal Transduct Res 1999. 19:975-93

» Wang, J-L, Cheng, H-F, Zhou, M-Z, McKanna, J.A. and Harris, R.C Increased cyclooxygenase-2 expression after subtotal renal ablation Am. J. Physiol 1998. 275:F613- F622

» Cheng, H-F, Wang, J-L, Vinson, G.P. and Harris, R.C Young spontaneous hypertensive rats (SHR) express increased type 1 angiotensin II receptors (AT1R) in renal proximal tubule Am. J. Physiol (Renal Physiol.) 1998. 274:F10-F17

» Mechanical stretch/relaxation stimulates a novel cellular renin-angiotensin system in cultured rat mesangial cell Experimental Nephrology 1998. 6:57-66

» Chen, J-K, Falck, J.R. Reddy, K.M., Capdevila, J.C. and Harris, R.C Epoxyeicosatrienoic Acids and their sulfonamide derivatives stimulate tyrosine phosphorylation and induce mitogenesis in renal epithelial cells 1998. J. Biol. Chem.:29254-29261

» Miyazaki, Y., Tsuchida, S., Nishimura, H., Pope, J.C., Harris, R.C., McKanna, J. M., Inagami, T., Hogan,B.L.M., Fogo, A. and Ichikawa, I Angiotensin induces the urinary peristaltic machinery during the perinatal period J. Clin. Invest 1998. 102:1489-1497

» Cheng, HF, Wang, JL, Vinson, GP, Harris, RC Young SHR express increased type 1 angiotensin II receptors in renal proximal tubule Am J Physiol 1998. 274:F10-7

» Becker, BN, Yasuda, T, Kondo, S, Vaikunth, S, Homma, T, Harris, RC Mechanical stretch/relaxation stimulates a cellular renin-angiotensin system in cultured rat mesangial cells Exp Nephrol 1998. 6:57-66

» McKanna, JA, Zhang, MZ, Wang, JL, Cheng, H, Harris, RC Constitutive expression of cyclooxygenase-2 in rat vas deferens Am J Physiol 1998. 275:R227-33

» Harris, RC, Wang, JL, Cheng, HF, Zhang, MZ, McKanna, JA Prostaglandins in macula densa function Kidney Int Suppl 1998. 67:S49-52

» Wang, JL, Cheng, HF, Zhang, MZ, McKanna, JA, Harris, RC Selective increase of cyclooxygenase-2 expression in a model of renal ablation Am J Physiol 1998. 275:F613-22

» Chen, JK, Falck, JR, Reddy, KM, Capdevila, J, Harris, RC Epoxyeicosatrienoic acids and their sulfonimide derivatives stimulate tyrosine phosphorylation and induce mitogenesis in renal epithelial cells J Biol Chem 1998. 273:29254-61

» Miyazaki, Y, Tsuchida, S, Nishimura, H, Pope, JC, Harris, RC, McKanna, JM, Inagami, T, Hogan, BL, Fogo, A, Ichikawa, I Angiotensin induces the urinary peristaltic machinery during the perinatal period J Clin Invest 1998. 102:1489-97

» Harris, RC, Becker, BN, Cheng, HF Acute and chronic mechanisms for regulating proximal tubule angiotensin II receptor expression J Am Soc Nephrol 1997. 8:306-13

» Zhang, MZ, Wang, JL, Cheng, HF, Harris, RC, McKanna, JA Cyclooxygenase-2 in rat nephron development Am J Physiol 1997. 273:F994-1002

» Sakai, M., Zhang, M. Homma, T., Garrick, B., Abraham, J.A. McKanna, J.A. and Harris, R.C Production of Heparin Binding Epidermal Growth Factor-like Growth Factor in the Early Phase of Regeneration Following Acute Renal Injury J. Clin. Invest. 1997. 99:2128-2138

» Harris, RC Growth factors and cytokines in acute renal failure Adv Ren Replace Ther 1997. 4:43-53

» Becker, BN, Cheng, HF, Harris, RC Apical ANG II-stimulated PLA2 activity and Na+ flux: a potential role for Ca2+-independent PLA2 Am J Physiol 1997. 273:F554-62

» Becker, BN, Kondo, S, Cheng, HF, Harris, RC Effect of glucose, pyruvate, and insulin on type 1 angiotensin II receptor expression in SV40-immortalized rabbit proximal tubule epithelial cells Kidney Int 1997. 52:87-92

» Takemura, T., Kondo, S., Homma, T., Sakai, M. and Harris, R.C The membrane bound form of heparin-binding epidermal growth factor-like growth factor (HB-EGF) promotes survival of cultured renal epithelial cells J. Biol. Chem. 1997. 272:31036-31042

» Takemura, T, Kondo, S, Homma, T, Sakai, M, Harris, RC The membrane-bound form of heparin-binding epidermal growth factor-like growth factor promotes survival of cultured renal epithelial cells J Biol Chem 1997. 272:31036-42

» Sakai, M, Zhang, M, Homma, T, Garrick, B, Abraham, JA, McKanna, JA, Harris, RC Production of heparin binding epidermal growth factor-like growth factor in the early phase of regeneration after acute renal injury. Isolation and localization of bioactive molecules J Clin Invest 1997. 99:2128-38

» Becker, BN, Harris, RC A potential mechanism for proximal tubule angiotensin II-mediated sodium flux associated with receptor-mediated endocytosis and arachidonic acid release Kidney Int Suppl 1996. 57:S66-72

» Cheng, H-F., Becker, B.N. and Harris, R.C Dopamine decreases expression of type 1 angiotensin II receptors in renal proximal tubule J. Clin. Invest 1996. 97:2745-2752

» Yasuda, T., Hondo, S. Homma, T. and Harris, R.C Regulation of extracellular matrix by mechanical stress in rat glomerular mesangial cells J. Clin.Invest. 1996. 98:1991-2000

» Harris, RC, Cheng, HF The intrarenal renin-angiotensin system: a paracrine system for the local control of renal function separate from the systemic axis Exp Nephrol 1996. 4 Suppl 1:2-7

» Cheng, HF, Becker, BN, Harris, RC Dopamine decreases expression of type-1 angiotensin II receptors in renal proximal tubule J Clin Invest 1996. 97:2745-52

» Yasuda, T, Kondo, S, Homma, T, Harris, RC Regulation of extracellular matrix by mechanical stress in rat glomerular mesangial cells J Clin Invest 1996. 98:1991-2000

» Harris, RC The macula densa: recent developments J Hypertens 1996. 14:815-22

» Cheng, HF, Becker, BN, Burns, KD, Harris, RC Angiotensin II upregulates type-1 angiotensin II receptors in renal proximal tubule J Clin Invest 1995. 95:2012-9

» Homma, T, Sakai, M, Cheng, HF, Yasuda, T, Coffey, RJ, Harris, RC Induction of heparin-binding epidermal growth factor-like growth factor mRNA in rat kidney after acute injury J Clin Invest 1995. 96:1018-25

» Becker, BN, Cheng, HF, Burns, KD, Harris, RC Polarized rabbit type 1 angiotensin II receptors manifest differential rates of endocytosis and recycling Am J Physiol 1995. 269:C1048-56

» Burns, KD, Capdevila, J, Wei, S, Breyer, MD, Homma, T, Harris, RC Role of cytochrome P-450 epoxygenase metabolites in EGF signaling in renal proximal tubule Am J Physiol 1995. 269:C831-40

» Harris, RC, Martinez-Maldonado, M Angiotensin II-mediated renal injury Miner Electrolyte Metab 1995. 21:328-35

» Homma, T., Sakai, M., Yasuda, T. Cheng, H-F., Coffey, Jr., R.J. and Harris, RC Heparin-binding epidermal growth factor-like growth factor mRNA increases in response to acute renal injury J. Clin. Invest. 1995. 96:1018-1025

» Cheng, H-F., Becker, B. N., Burns, K.D. and Harris, RC Angiotensin II regulates its receptor sites inrabbit proximal tubule J. Clin. Invest 1995. 95:2012-2019

» Threadgill, D.W., Dlugosz, A.A., Hansen, L., Tennenbaum, T., Lichi, U., Yee, D, LeMantia, C., Mourton, T., Herrup, K., Harris, RC, Barnard, J.A., Yuspa,S.H., Coffey, and Magnuson, T Targeted disruption of mouse EGF-receptor: Evidence that genetic background affects mutant phenotype Science 1995. 269:230-234

» Cheng, HF, Burns, KD, Harris, RC Reduced proximal tubule angiotensin II receptor expression in streptozotocin-induced diabetes mellitus Kidney Int 1994. 46:1603-10

» Akai, Y, Homma, T, Burns, KD, Yasuda, T, Badr, KF, Harris, RC Mechanical stretch/relaxation of cultured rat mesangial cells induces protooncogenes and cyclooxygenase Am J Physiol 1994. 267:C482-90

» Harris, RC, Ismail, N Extrarenal complications of the nephrotic syndrome Am J Kidney Dis 1994. 23:477-97

» Harris, RC, Akai, Y, Yasuda, T, Homma, T Role of physical factors in the regulation of mesangial cell growth and the interaction with vasoactive agents Exp Nephrol 1994. 2:104

» Harris, RC, Akai, Y, Yasuda, T, Homma, T The role of physical forces in alterations of mesangial cell function Kidney Int Suppl 1994. 45:S17-21

» Harris, R.C., McKanna, J.A., Akai, Y., Jacobson, H.R., Dubois, R.N. and Breyer, M.D Cyclooxygenase-2 is associated with the macula densa of rat kidney and increases with salt restriction J. Clin. Invest 1994. 94:2504-2510

» Harris, RC, McKanna, JA, Akai, Y, Jacobson, HR, Dubois, RN, Breyer, MD Cyclooxygenase-2 is associated with the macula densa of rat kidney and increases with salt restriction J Clin Invest 1994. 94:2504-10

» Burns, KD, Inagami, T, Harris, RC Cloning of a rabbit kidney cortex AT1 angiotensin II receptor that is present in proximal tubule epithelium Am J Physiol 1993. 264:F645-54

» Homma, T, Zhang, JY, Shimizu, T, Prakash, C, Blair, IA, Harris, RC Cyclooxygenase-derived metabolites of 8,9-epoxyeicosatrienoic acid are potent mitogens for cultured rat glomerular mesangial cells Biochem Biophys Res Commun 1993. 191:282-8

» Burns, K.D., Inagami, T. and Harris, R.C Cloning of a rabbit kidney cortex AT1 angiotensin II receptor that is present in proximal tubule epithelium Am. J. Physiol 1993. 264:F645-F654

» Harris, RC, Burns, KD, Alattar, M, Homma, T, Nakamura, T Hepatocyte growth factor stimulates phosphoinositide hydrolysis and mitogenesis in cultured renal epithelial cells Life Sci 1993. 52:1091-100

» Burns, KD, Homma, T, Harris, RC The intrarenal renin-angiotensin system Semin Nephrol 1993. 13:13-30

» Takahashi, K, Harris, RC, Capdevila, JH, Karara, A, Makita, K, Jacobson, HR, Munger, KA, Badr, KF Induction of renal arachidonate cytochrome P-450 epoxygenase after uninephrectomy: counterregulation of hyperfiltration J Am Soc Nephrol 1993. 3:1496-500

» McKanna, JA, Chuncharunee, A, Munger, KA, Breyer, JA, Cohen, S, Harris, RC Localization of p35 (annexin I, lipocortin I) in normal adult rat kidney and during recovery from ischemia J Cell Physiol 1992. 153:467-76

» Harris, RC, Haralson, MA, Badr, KF Continuous stretch-relaxation in culture alters rat mesangial cell morphology, growth characteristics, and metabolic activity Lab Invest 1992. 66:548-54

» Homma, T, Akai, Y, Burns, KD, Harris, RC Activation of S6 kinase by repeated cycles of stretching and relaxation in rat glomerular mesangial cells. Evidence for involvement of protein kinase C J Biol Chem 1992. 267:23129-35

» Harris, R.C S6 kinase activity in proximal tubule cells. Evidence for activation by epidermal growth factor and angiotensin II in vitro and by contralateral nephrectomy in vivo Am. J. Physiol. 1992. 263:F127-F134

» Homma, T. Akai, Y. Burns, K.D. and Harris, R.C Activation of S6 kinase activity by repeated cycles of stretching and relaxation in cultured rat glomerular mesangial cells:Evidence for involvement of protein kinase C 5J. Biol.Chem. 1992. 267:23129-2313

» Homma, T, Harris, RC Time-dependent biphasic regulation of Na+/K+/Cl- cotransport in rat glomerular mesangial cells J Biol Chem 1991. 266:13553-9

» Homma, T. and Harris, R.C Time-dependent biphasic regulation of Na+/K+/Cl- cotransport in rat glomerular mesangial cells J. Biol. Chem. 1991. 266:13553-13559

» Awazu, M, Kon, V, Harris, RC, Imada, T, Inagami, T, Ichikawa, I Renal sympathetic nerves modulate glomerular ANP receptors and filtration Am J Physiol 1991. 261:F29-35

» Harris, RC Potential physiologic roles for epidermal growth factor in the kidney Am J Kidney Dis 1991. 17:627-30

» Homma, T., Burns, K. and Harris R.C Agonist stimulation of Na/K/Cl cotransport in cultured rat mesangial cells: Evidence for protein kinase C-dependent and calcium/calmodulin-dependent pathways J. Biol. Chem. 1990. 265::17613-17620

» Kon, V., Harris, R.C. and Ichikawa, I A regulatory role for large vessels in organ circulation: Endothelial cells of the main renal artery modulate intrarenal hemodynamics in the rat J. Clin. Invest 1990. 85:1728-1733

» Kon, V, Harris, RC, Ichikawa, I A regulatory role for large vessels in organ circulation. Endothelial cells of the main renal artery modulate intrarenal hemodynamics in the rat J Clin Invest 1990. 85:1728-33

» Harris, RC, Homma, T, Jacobson, HR, Capdevila, J Epoxyeicosatrienoic acids activate Na+/H+ exchange and are mitogenic in cultured rat glomerular mesangial cells J Cell Physiol 1990. 144:429-37

» Harris, RC, Badr, KF Recovery of prostaglandin synthesis in rat glomerular mesangial cells after aspirin inhibition: induction of cyclooxygenase activity by serum and epidermal growth factor Prostaglandins 1990. 39:213-22

» Harris, RC, Munger, KA, Badr, KF, Takahashi, K Mediation of renal vascular effects of epidermal growth factor by arachidonate metabolites FASEB J 1990. 4:1654-60

» Badr, KF, Murray, JJ, Breyer, MD, Takahashi, K, Inagami, T, Harris, RC Mesangial cell, glomerular and renal vascular responses to endothelin in the rat kidney. Elucidation of signal transduction pathways J Clin Invest 1989. 83:336-42

» Badr, KF, DeBoer, DK, Takahashi, K, Harris, RC, Fogo, A, Jacobson, HR Glomerular responses to platelet-activating factor in the rat: role of thromboxane A2 Am J Physiol 1989. 256:F35-43

» Harris, RC, Daniel, TO Epidermal growth factor binding, stimulation of phosphorylation, and inhibition of gluconeogenesis in rat proximal tubule J Cell Physiol 1989. 139:383-91

» Badr, KF, Mong, S, Hoover, RL, Schwartzberg, M, Ebert, J, Jacobson, HR, Harris, RC Leukotriene D4 binding and signal transduction in rat glomerular mesangial cells Am J Physiol 1989. 257:F280-7

» Badr, K.F., Murray, J.J., Breyer, M.D., Takahashi, K., Inagami, T. and Harris, R.C Mesangial cell, glomerular and renal vascular responses to endothelin in the rat kidney: Elucidation of signal transduction pathways J. Clin.Invest 1989. 83:336-342

» Harris, R.C., Hoover, R.L., Jacobson, H.R. and Badr, K.F Evidence for glomerular actions of epidermal growth factor in the rat J. Clin Invest. 1988. 82:1028-1039