Selected Publications
» Mundy GR Hypercalcemia of Malignancy In: Clinical Endocrine Oncology. May I, Turner H, Wass J, eds (2nd edition). Blackwell (in press) . :
» Mundy GR, Sterling JA Metastatic Solid Tumors to Bone In: ASBMR Primer on the Metabolic Bone Diseases and Disorders of Mineral Metabolism (7th Edition) Clifford Rosen (ed.), Lippincott Williams and Wilkins Publishers (in press) . :
» Mundy GR, Edwards CM, Edwards JR, Lynch CC, Sterling JA, Zhuang J Localized Osteolysis Principles of Bone Biology. (3rd Edition) Biezikian J, Craig Z, Martin TJ (eds) Academic Press, Inc., San Diego, CA (in press) . :
» Mundy GR, Edwards JR PTH-related Peptide (PTHrP) in Hypercalcemia Journal of the American Society of Nephrology (in press) . :
» Edwards CM, Zhuang J, Mundy GR The pathogenesis of the bone disease of multiple myeloma. Bone e pub 2008. 42:1007-13
» Mundy GR, Yang X Hedgehog coordination of postnatal osteoclast and osteoblast activities. Dev. Cell 2008. 14:637-8
» Mundy, GR, Yang, X Hedgehog coordination of postnatal osteoclast and osteoblast activities Dev Cell 2008. 14:637-8
» Edwards, CM, Edwards, JR, Lwin, ST, Esparza, J, Oyajobi, BO, McCluskey, B, Munoz, S, Grubbs, B, Mundy, GR Increasing Wnt signaling in the bone marrow microenvironment inhibits the development of myeloma bone disease and reduces tumor burden in bone in vivo Blood 2008. 111:2833-42
» Mundy, GR, Edwards, JR PTH-related peptide (PTHrP) in hypercalcemia J Am Soc Nephrol 2008. 19:672-5
» Edwards, CM, Zhuang, J, Mundy, GR The pathogenesis of the bone disease of multiple myeloma Bone 2008. 42:1007-13
» Zhang, Y, Padalecki, SS, Chaudhuri, AR, De Waal, E, Goins, BA, Grubbs, B, Ikeno, Y, Richardson, A, Mundy, GR, Herman, B Caspase-2 deficiency enhances aging-related traits in mice Mech Ageing Dev 2007. 128:213-21
» Garrett IR, Gutierrez GE, Rossini G, Nyman J, McCluskey B, Flores A, Mundy GR Locally Delivered Lovastatin Nanoparticles Enhance Fracture Healing in Rats J Orthopaedic Research 2007. 10:1351-1357
» Oyajobi BO, Garrett IR, Gupta A, Flores A, Esparza J, Munoz S, Zhao M, Mundy GR Stimulation of new bone formation by the proteasome inhibitor, bortezomib: implications for myeloma bone disease British Journal of Haematology 2007. 139:434-438
» Mundy GR, Edwards JR The Osteoclast-Not Always Guilty Cell Metabolism 2007. 6(3):157-9
» Mundy GR Osteoporosis and Inflammation Nutrition Review 2007. 65:S147-51
» Mundy, GR Osteoporosis and inflammation Nutr Rev 2007. 65:S147-51
» Mundy, GR, Edwards, JR The osteoclast-not always guilty Cell Metab 2007. 6:157-9
» Edwards CM, Edwards JR, Esparza J, Oyajobi BO, McCluskey B, Munoz S, Grubbs B, Mundy GR Increasing Wnt signalling in the bone marrow microenvironment inhibits the development of myeloma bone disease and reduces tumor burden in bone in vivo. Blood 2007. (epublication ahead of print):
» Mundy GR, Oyajobi BO, Gutierrez G, Sterling JA, Padalecki S, Elefteriou F, Zhao M Cytokines and bone remodeling In: Osteoporosis 3rd Edition, Marcus R, Feldman D, Nelson D, Rosen CJ (eds), Elsevier 2007. 1(13):491-515
» Mundy GR, Gutierrez GE, Garrett IR, Gallwitz W, Rossini G, Christiansen C, Langenberg Andria Proteasome Inhibitors Stimulate both Bone Formation and Hair Growth by Similar Mechanisms Skeletal Biology and Medicine, Part B, Disease Mechanisms and Therapeutic Challenges. Zaidi M (ed) Annals of the New York Academy of Sciences 2007. 1117:298-301
» Martin, TJ, Mundy, GR Bone metastasis: can osteoclasts be excluded Nature 2007. 445:E19; discussion E19-20
» Sterling, JA, Oyajobi, BO, Grubbs, B, Padalecki, SS, Munoz, SA, Gupta, A, Story, B, Zhao, M, Mundy, GR The hedgehog signaling molecule Gli2 induces parathyroid hormone-related peptide
expression and osteolysis in metastatic human breast cancer cells Cancer Res 2006. 66:7548-53
» Gutierrez GE, Mundy B, rossini G, Garrett IR, Chen ST, Mundy GR Red yeast rice stimulates bone formation in rats Nutrition Research 2006. 26:124-129
» Mundy, GR, Elefteriou, F Boning up on ephrin signaling Cell 2006. 126:441-3
» Mundy, GR Nutritional modulators of bone remodeling during aging Am J Clin Nutr 2006. 83:427S-430S
» Bandyopadhyay, A, Agyin, JK, Wang, L, Tang, Y, Lei, X, Story, BM, Cornell, JE, Pollock, BH, Mundy, GR, Sun, LZ Inhibition of pulmonary and skeletal metastasis by a transforming growth factor-beta
type I receptor kinase inhibitor Cancer Res 2006. 66:6714-21
» Gutierrez, GE, Lalka, D, Garrett, IR, Rossini, G, Mundy, GR Transdermal application of lovastatin to rats causes profound increases in
bone formation and plasma concentrations Osteoporos Int 2006. 17:1033-42
» Mundy, GR In memoriam; Dr. Gideon Rodan Bone 2006. 38:297-99
» Zhao, M, Qiao, M, Harris, SE, Chen, D, Oyajobi, BO, Mundy, GR The zinc finger transcription factor Gli2 mediates bone morphogenetic protein
2 expression in osteoblasts in response to hedgehog signaling Mol Cell Biol 2006. 26:6197-208
» Rowe, PS, Garrett, IR, Schwarz, PM, Carnes, DL, Lafer, EM, Mundy, GR, Gutierrez, GE Surface plasmon resonance (SPR) confirms that MEPE binds to PHEX via the MEPE-ASARM
motif: a model for impaired mineralization in X-linked rickets (HYP) Bone 2005. 36:33-46
» Oyajobi BO, Shipman CM, Mundy GR Recent insights into myeloma bone disease IBMS Bone KEy 2005. :10.1138/20050161
» Mundy, GR How can bone turnover markers be best utilized for prediction of skeletal events
in patients with solid tumors Nat Clin Pract Oncol 2005. 2:242-3
» Mundy GR Bone Disease of multiple myeloma In: A Comprehensive Guide to Sydney 2005, Review of the 10th International Myeloma Workshop. International Myeloma Foundation (publisher) 2005. :
» Shipman, CM, Oyajobi, BO, Mundy, GR Advances in the management of myeloma bone disease Expert Opin Pharmacother 2005. 6:2781-91
» Coleman RE, Martin TJ, Mundy GR Meeting report from the Vth International Conference on cancer-induced bone disease: March 20-24, 2005 in Davos, Switzerland IBMS BoneKEy 2005. :10.1138/20050158
» Rowe, PS, Kumagai, Y, Gutierrez, G, Garrett, IR, Blacher, R, Rosen, D, Cundy, J, Navvab, S, Chen, D, Drezner, MK, Quarles, LD, Mundy, GR MEPE has the properties of an osteoblastic phosphatonin and minhibin Bone 2004. 34:303-19
» Bauer, DC, Mundy, GR, Jamal, SA, Black, DM, Cauley, JA, Ensrud, KE, van der Klift, M, Pols, HA Use of statins and fracture: results of 4 prospective studies and cumulative
meta-analysis of observational studies and controlled trials Arch Intern Med 2004. 164:146-52
» Mundy, GR The evolving role of bisphosphonates: cancer treatment-induced bone loss Oncology (Williston Park) 2004. 18:9-10
» Mundy GR Realising the potential of anti-host cell therapy Cell Today 2004. (Supplement 1):6-8
» Zhao, M, Qiao, M, Harris, SE, Oyajobi, BO, Mundy, GR, Chen, D Smurf1 inhibits osteoblast differentiation and bone formation in vitro and
in vivo J Biol Chem 2004. 279:12854-9
» Oyajobi B, Mundy GR Pathophysiology of myeloma bone disease Multiple Myeloma and Related Disorders (2nd edition), Durie BS, Gahrton G, Samson DS (eds). Arnold, London 2004. Part 2:74-88
» Mori, Y, Shimizu, N, Dallas, M, Niewolna, M, Story, B, Williams, PJ, Mundy, GR, Yoneda, T Anti-alpha4 integrin antibody suppresses the development of multiple myeloma
and associated osteoclastic osteolysis Blood 2004. 104:2149-54
» Myoui, A, Nishimura, R, Williams, PJ, Hiraga, T, Tamura, D, Michigami, T, Mundy, GR, Yoneda, T C-SRC tyrosine kinase activity is associated with tumor colonization in bone
and lung in an animal model of human breast cancer metastasis Cancer Res 2003. 63:5028-33
» Feng, JQ, Xing, L, Zhang, JH, Zhao, M, Horn, D, Chan, J, Boyce, BF, Harris, SE, Mundy, GR, Chen, D NF-kappaB specifically activates BMP-2 gene expression in growth plate chondrocytes
in vivo and in a chondrocyte cell line in vitro J Biol Chem 2003. 278:29130-5
» Oyajobi, BO, Franchin, G, Williams, PJ, Pulkrabek, D, Gupta, A, Munoz, S, Grubbs, B, Zhao, M, Chen, D, Sherry, B, Mundy, GR Dual effects of macrophage inflammatory protein-1alpha on osteolysis and tumor
burden in the murine 5TGM1 model of myeloma bone disease Blood 2003. 102:311-9
» Kakonen SM, Mundy GR Mechanisms of osteolytic bone metastases in breast carcinoma Cancer 2003. 97:834-9
» Mundy, GR Endothelin-1 and osteoblastic metastasis Proc Natl Acad Sci U S A 2003. 100:10588-9
» Lane N, Dequeker J, Mundy GR Bone Structure and Function Rheumatology, 3rd edition, Hochberg M, Silman A, Smolen J, Weinblatt M, Weisman M (eds), Chapter 192 2003. :2029-2041
» Zhao, M, Qiao, M, Oyajobi, BO, Mundy, GR, Chen, D E3 ubiquitin ligase Smurf1 mediates core-binding factor alpha1/Runx2 degradation
and plays a specific role in osteoblast differentiation J Biol Chem 2003. 278:27939-44
» Oyajobi, BO, Mundy, GR Receptor activator of NF-kappaB ligand, macrophage inflammatory protein-1alpha,
and the proteasome: novel therapeutic targets in myeloma Cancer 2003. 97:813-7
» Chen D, Zhao M, Mundy GR Bone Morphogenic Proteins Encyclopedia of Hormones, HL Henry, AW Norman (eds). Academic Press, San Diego, CA 2003. :205-209
» Mundy GR, Chen D, Oyajobi BO Bone remodeling Favus, M (ed): ASBMR Primer on the Metabolic Bone Diseases and Disorders of Mineral Metabolism (5th edition). ASBMR, Washington, D.C. Chapter 7 2003. :46-58
» Mundy GR Myeloma Bone Disease - Update 2003 Myeloma Today 2003. 4:
» Garrett, IR, Chen, D, Gutierrez, G, Zhao, M, Escobedo, A, Rossini, G, Harris, SE, Gallwitz, W, Kim, KB, Hu, S, Crews, CM, Mundy, GR Selective inhibitors of the osteoblast proteasome stimulate bone formation
in vivo and in vitro J Clin Invest 2003. 111:1771-82
» Gallwitz, WE, Guise, TA, Mundy, GR Guanosine nucleotides inhibit different syndromes of PTHrP excess caused by
human cancers in vivo J Clin Invest 2002. 110:1559-72
» Michigami, T, Hiraga, T, Williams, PJ, Niewolna, M, Nishimura, R, Mundy, GR, Yoneda, T The effect of the bisphosphonate ibandronate on breast cancer metastasis to
visceral organs Breast Cancer Res Treat 2002. 75:249-58
» Mundy, GR Metastasis to bone: causes, consequences and therapeutic opportunities Nat Rev Cancer 2002. 2:584-93
» Garrett, IR, Mundy, GR The role of statins as potential targets for bone formation Arthritis Res 2002. 4:237-40
» Zhao, M, Harris, SE, Horn, D, Geng, Z, Nishimura, R, Mundy, GR, Chen, D Bone morphogenetic protein receptor signaling is necessary for normal murine
postnatal bone formation J Cell Biol 2002. 157:1049-60
» Mundy GR, Yoneda T, Guise TA, Oyajobi B Local factors in skeletal malignancy Principles of Bone Biiology 2 E. Bilezikian J, Raisz L, Rodan G (eds). Academic Press, Inc., San Diego, CA 2002. Chapter 61:1093-1104
» Dallas, SL, Rosser, JL, Mundy, GR, Bonewald, LF Proteolysis of latent transforming growth factor-beta (TGF-beta )-binding protein-1
by osteoclasts. A cellular mechanism for release of TGF-beta from bone matrix J Biol Chem 2002. 277:21352-60
» Mundy, GR Directions of drug discovery in osteoporosis Annu Rev Med 2002. 53:337-54
» Mundy GR, Stewart AF Common disorders of Bone and Mineral Metabolism Comprehensive Clinical Endocrinology, Besser GM, Thorner MO, eds. (3rd edition), Mosby, Edinburgh, Scotland. 2002. Chapter 34:501-516
» Mundy GR Does clondronate treatment affect non-boney metastases in breast cancer? Bone KEy 2002 Aug 2810.1138/ibmske; 2002058v1 2002. :
» Black DM, Cosman F, Eastell R, Mundy GR and Rosen CJ Meeting report from the National Osteoporosis Foundation 5th International Symposium on Clinical Advances in Osteoporosis IBMS BoneKEy 2002. :10.1138/2002038
» Mundy, GR Bisphosphonates and tumor burden J Clin Oncol 2002. 20:3191-2
» Mundy, GR Osteoporosis: pathophysiology and non-pharmacological management Best Pract Res Clin Rheumatol 2001. 15:727-45
» Mundy GR, Gutierrez G, Gallwitz W, Feng J, Chen D, Garrett R, Harris S Antler-derived bone growth factors and their potential for use in osteoporosis Antler Science and Product Technology, Sim JS, Sunwoo HH, Hudson RJ, Jeon BT (eds.) ASPTRC 2001. :
» Mundy, GR, Chen, D, Zhao, M, Dallas, S, Xu, C, Harris, S Growth regulatory factors and bone Rev Endocr Metab Disord 2001. 2:105-15
» Ghosh-Choudhury, N, Choudhury, GG, Harris, MA, Wozney, J, Mundy, GR, Abboud, SL, Harris, SE Autoregulation of mouse BMP-2 gene transcription is directed by the proximal
promoter element Biochem Biophys Res Commun 2001. 286:101-8
» Xu, SC, Harris, MA, Rubenstein, JL, Mundy, GR, Harris, SE Bone morphogenetic protein-2 (BMP-2) signaling to the Col2alpha1 gene in chondroblasts
requires the homeobox gene Dlx-2 DNA Cell Biol 2001. 20:359-65
» Garrett, IR, Gutierrez, G, Mundy, GR Statins and bone formation Curr Pharm Des 2001. 7:715-36
» Oyajobi, BO, Anderson, DM, Traianedes, K, Williams, PJ, Yoneda, T, Mundy, GR Therapeutic efficacy of a soluble receptor activator of nuclear factor kappaB-IgG
Fc fusion protein in suppressing bone resorption and hypercalcemia in a model of humoral hypercalcemia
of malignancy Cancer Res 2001. 61:2572-8
» Hiraga, T, Williams, PJ, Mundy, GR, Yoneda, T The bisphosphonate ibandronate promotes apoptosis in MDA-MB-231 human breast
cancer cells in bone metastases Cancer Res 2001. 61:4418-24
» Mundy, GR, Yoneda, T, Hiraga, T Preclinical studies with zoledronic acid and other bisphosphonates: impact
on the bone microenvironment Semin Oncol 2001. 28:35-44
» Mundy GR Advances in the biology and treatment of metastatic bone disease Proceedings of ASCO, 37th Annual Meeting, Spring 2001. :164-172
» Mundy GR Maintaining the balance Orgyn 2001. 3:32-36
» Mundy GR Research needs in myeloma Oncology Spectrum 2001. 2:2:81-110
» Mundy G Preclinical models of bone metastases Proceedings of the San Antonio Roundtable Meeting. Semin Oncol 2001. 28:2-8
» Mundy GR Bone metabolism, bone disease and the bisphosphonates Comprehensive Buide to Banff: Unverstanding the VIIIth Internatinal Myeloma Workshop-8th International Bone Conference 2001. :16-17
» Mundy GR, Oyajobi B Other local and ectopic hormone syndromes associated with hypercalcemia The Parathyroids: Basic and Clinical Concepts, Bilezikian, JP (2nd edition), Academic Press, Inc., San Diego, CA 2001. Chapter 43:691-705
» Mundy GR Osteoporosis: pathophysiology and non-pharmacological management Best Pract Res Clinic Rheumatol. 2001. 15 (5):727-745
» Mundy GR Statins and their potential for osteoporosis IBMS BoneKEy 2001. :10.1138/2001029
» Mundy GR, Chen D, Zhao M, Dallas S, Xu C, Harris S Growth regulatory factors and bone Reviews in Endocrine and Metabolic Disorders. Edited by Derek LeRoith 2001. 2:105-115
» Bruder JM, Guise TA, Mundy GR Mineral metabolism Endocrinology and Metabolism, 4th edition, McGraw Hill, Felig P, Grohman L (eds.) 2001. :1079-1179
» Mundy GR, Oyajobi B, Traianedes K, Dallas S, Chen D Cytokines and bone remodeling Osteoporosis, 2E, Marcus B, Kelsey J, Feldman D (eds), Academic Press, New York 2001. 13:373-470
» Mundy GR Bone Metabolism Myeloma Today 2001. 4:
» Mundy, GR Statins and their potential for osteoporosis Bone 2001. 29:495-7
» Maddox, E, Zhan, M, Mundy, GR, Drohan, WN, Burgess, WH Optimizing human demineralized bone matrix for clinical application Tissue Eng 2000. 6:441-8
» Mundy GR Prospects for new therapies in bone diseases Proceedings of the 11th Vitamin D Workshop, Nashville 2000. :
» Ji, X, Chen, D, Xu, C, Harris, SE, Mundy, GR, Yoneda, T Patterns of gene expression associated with BMP-2-induced osteoblast and adipocyte
differentiation of mesenchymal progenitor cell 3T3-F442A J Bone Miner Metab 2000. 18:132-9
» Diel, IJ, Mundy, GR Bisphosphonates in the adjuvant treatment of cancer: experimental evidence
and first clinical results. International Bone and Cancer Study Group (IBCG) Br J Cancer 2000. 82:1381-6
» Mundy GR Structure and physiology of the normal skeleton Mundy GR, Rubens RD (eds). Cancer and the Skeleton. Martin Dunitz, London 2000. :1-20
» Diel IJ, Mundy GR Bisphosphonates in the adjuvant treatment of cancer: experimental evidence and first clinical results. International Bone and Cancer Study Group (IBCG) Br J Cancer 2000. 82:1381-1386
» Chen D, Zhao M, Oyajobi B, Mundy GR Update in Bone Cell Biology Osteoporosis and Bone Biology, edited by Juliet Compston and Stuart Ralston. International Medical Press, United Kingdom 2000. :29-41
» Mundy GR, Guise TA Pathophysiology of bone metastasis Mundy GR, Rubens RD (eds.) Cancer and the Skeleton 2000. :43-64
» Mundy, GR Secondary osteoporosis: the potential relevance of leptin and low body weight Ann Intern Med 2000. 133:828-30
» Marzia, M, Sims, NA, Voit, S, Migliaccio, S, Taranta, A, Bernardini, S, Faraggiana, T, Yoneda, T, Mundy, GR, Boyce, BF, Baron, R, Teti, A Decreased c-Src expression enhances osteoblast differentiation and bone formation J Cell Biol 2000. 151:311-20
» Mundy, GR Pathogenesis of osteoporosis and challenges for drug delivery Adv Drug Deliv Rev 2000. 42:165-73
» Michigami, T, Shimizu, N, Williams, PJ, Niewolna, M, Dallas, SL, Mundy, GR, Yoneda, T Cell-cell contact between marrow stromal cells and myeloma cells via VCAM-1
and alpha(4)beta(1)-integrin enhances production of osteoclast-stimulating activity Blood 2000. 96:1953-60
» Dallas, SL, Keene, DR, Bruder, SP, Saharinen, J, Sakai, LY, Mundy, GR, Bonewald, LF Role of the latent transforming growth factor beta binding protein 1 in fibrillin-containing
microfibrils in bone cells in vitro and in vivo J Bone Miner Res 2000. 15:68-81
» Mundy GR, Oyajobi B Pathophysiology of myeloma bone disease Mundy GR, Rubens RD (eds.) Cancer and the Skeleton, Martin Dunitz, London 2000. :21-32
» Mundy GR, Guise TA Biology of bone metastases Lippman M, Morrow M, Osborne CK. Diseases of the Breast, 2nd Edition, Lippincott-Raven, Philadelphia 2000. :911-920
» Mundy GR Cytokines, Growth Factors, and Malignancy Skeletal Growth Factors. Edited by Ernesto Canalis. Lippincott Williams & Wilkins, Philadelphia 2000. :
» Bruder JM and Mundy GR Statins and their effects on bone formation The Endocrinologist 2000. 10:225-228
» Oyajobi, BO, Deng, JH, Dallas, SL, Jenson, HB, Mundy, GR, Gao, SJ Absence of herpesvirus DNA sequences in the 5T murine model of human multiple
myeloma Br J Haematol 2000. 109:413-9
» Mundy GR Cellular and Molecular Regulation of Bone Turnover Bone 1999. 24 (5 Suppl):35S-38S
» Mundy GR, Garrett IR, Harris SE, Chan J, Chen D, Rossini G, Boyce BF, Zhao M, Gutierrez G Stimulation of bone formation in vitro and in rodents by statins Science 1999. 286:1946-1949
» Mundy, GR, Guise, TA Hormonal control of calcium homeostasis Clin Chem 1999. 45:1347-52
» Mundy, GR Bisphosphonates as cancer drugs Hosp Pract (Minneap) 1999. 34:81-4, 88-9, 93-4
» Dallas, SL, Garrett, IR, Oyajobi, BO, Dallas, MR, Boyce, BF, Bauss, F, Radl, J, Mundy, GR Ibandronate reduces osteolytic lesions but not tumor burden in a murine model
of myeloma bone disease Blood 1999. 93:1697-706
» Mundy, GR Bisphosphonates as anticancer drugs Expert Opin Investig Drugs 1999. 8:2009-2015
» Dunstan, CR, Boyce, R, Boyce, BF, Garrett, IR, Izbicka, E, Burgess, WH, Mundy, GR Systemic administration of acidic fibroblast growth factor (FGF-1) prevents
bone loss and increases new bone formation in ovariectomized rats J Bone Miner Res 1999. 14:953-9
» Mundy, GR Cellular and molecular regulation of bone turnover Bone 1999. 24:35S-38S
» Yin, JJ, Selander, K, Chirgwin, JM, Dallas, M, Grubbs, BG, Wieser, R, Massagu??, J, Mundy, GR, Guise, TA TGF-beta signaling blockade inhibits PTHrP secretion by breast cancer cells
and bone metastases development J Clin Invest 1999. 103:197-206
» Mundy GR, Yoneda T, Guise T Hypercalcemia in hematologic malignancies and in solid tumors associated with extensive localized bone destruction Primer on the Metabolic Bone Diseases and Disorders of Metabolism. Lippincott-Raven, Philadelphia 1999. :
» Mundy Bone Remodeling Primer on the Metabolic Bone Diseases and Disorders of Metabolism. Lippincott-Raven Publishers, Philadelphia 1999. :
» Mundy, GR What can we learn from bone biology for the treatment for osteoporosis Osteoporos Int 1999. 9 Suppl 2:S40-7
» Guise TA, Mundy GR Disorder of Calcium Metabolism The Kidney, Physiology and Pathophysiology. 3rd Edition. D. Seldin & G. Giebisch (eds). Lippincott-Raven, Philadelphia 1998. :1811-39
» Mundy GR Pathology of Skeletal Metastasis Skeletal Manifestations of Malignancy - Interactive Medical Communications 1998. Winter:1-4
» Mundy GR Future strategies for the treatment of osteoporosis Osteoporosis. Stevenson Jr, Lindsay R (eds.), Chapman and Hall Publishers 1998. Chapter 19:365-376
» Mundy GR, Reasner CA Osteopetrosis Internal Medicine, J.H. Stein, (ed.) 5th edition, Mosby Publishers, Chapter 319 1998. :1958-1959
» Mundy GR, Reasner CA Fibrous dysplasia Internal Medicine, J.H. Stein, (ed.) 5th edition, Mosby Publishers, Chapter 320 1998. :1960-1961
» Mundy Gr Myeloma bone disease European J Cancer 1998. 34:246-251
» Mundy GR, Reasner CA Physiology of Bone and Mineral Homeostasis Internal Medicine, J.H. Stein (ed.) 5th edition, Mosby Publishers, Chapter 283 1998. :1714-1721
» Mundy GR, Reasner CA Diagnostic Approach to Bone and Mineral Disorders Internal Medicine, J.H. Stein, (ed.) 5th edition, Mosby Publishers, Chapter 286 1998. :1744-1748
» Mundy GR The Article Reviewed. "Use of Bisphosphonates in Patients with Metastatic Bone Disease." Berenson/Lipton Oncology 1998. 11:1580-1581
» Mundy GR, Reasner CA Malignant Disease and the Skeleton Internal Medicine, J.H. Stein, (ed.), 5th edition, Mosby Publishers, Chapter 323 1998. :1971-1974
» Mundy GR, Guise TA Role of PTH-rP in the hypercalcemia of malignancy and osteolytic bone disease Endocrine-Related Cancer 1998. 5:15-26
» Mundy, GR Myeloma bone disease Eur J Cancer 1998. 34:246-51
» Traianedes, K, Dallas, MR, Garrett, IR, Mundy, GR, Bonewald, LF 5-Lipoxygenase metabolites inhibit bone formation in vitro Endocrinology 1998. 139:3178-84
» Xu, C, Ji, X, Harris, MA, Mundy, GR, Harris, SE A clonal chondrocytic cell line derived from BMP-2/T antigen-expressing transgenic
mouse In Vitro Cell Dev Biol Anim 1998. 34:359-63
» Mbalaviele, G, Nishimura, R, Myoi, A, Niewolna, M, Reddy, SV, Chen, D, Feng, J, Roodman, D, Mundy, GR, Yoneda, T Cadherin-6 mediates the heterotypic interactions between the hemopoietic osteoclast
cell lineage and stromal cells in a murine model of osteoclast differentiation J Cell Biol 1998. 141:1467-76
» Mundy, GR "Hard days on the endless frontier" revisited FASEB J 1998. 12:262-3
» Guise, TA, Mundy, GR Cancer and bone Endocr Rev 1998. 19:18-54
» Body, JJ, Bartl, R, Burckhardt, P, Delmas, PD, Diel, IJ, Fleisch, H, Kanis, JA, Kyle, RA, Mundy, GR, Paterson, AH, Rubens, RD Current use of bisphosphonates in oncology. International Bone and Cancer Study
Group J Clin Oncol 1998. 16:3890-9
» Mundy, GR, Yoneda, T Bisphosphonates as anticancer drugs N Engl J Med 1998. 339:398-400
» Chen, D, Ji, X, Harris, MA, Feng, JQ, Karsenty, G, Celeste, AJ, Rosen, V, Mundy, GR, Harris, SE Differential roles for bone morphogenetic protein (BMP) receptor type IB and
IA in differentiation and specification of mesenchymal precursor cells to osteoblast and adipocyte lineages J Cell Biol 1998. 142:295-305
» Nishimura, R, Moriyama, K, Yasukawa, K, Mundy, GR, Yoneda, T Combination of interleukin-6 and soluble interleukin-6 receptors induces differentiation
and activation of JAK-STAT and MAP kinase pathways in MG-63 human osteoblastic cells J Bone Miner Res 1998. 13:777-85
» Nishimura, R, Kato, Y, Chen, D, Harris, SE, Mundy, GR, Yoneda, T Smad5 and DPC4 are key molecules in mediating BMP-2-induced osteoblastic differentiation
of the pluripotent mesenchymal precursor cell line C2C12 J Biol Chem 1998. 273:1872-9
» Mundy GR Introduction to the Osteoporosis Guidelines Symposium 1998. :
» Mundy GR Foreward Arnett Tr, Henderson B (eds). Methods in Bone Biology. Chapman & Hall, ix, London 1998. :
» Dequeker J, Mundy GR Bone Structure and Function Rheumatology: Management of Rheumatic Diseases, Klippel JH, Dieppe PA (eds) Brooks PM, Gerber LH (section eds), 2nd Edition, Mosby-Year Book Europe Limited, London 1997. 34:1-12
» Kato, Y, Windle, JJ, Koop, BA, Mundy, GR, Bonewald, LF Establishment of an osteocyte-like cell line, MLO-Y4 J Bone Miner Res 1997. 12:2014-23
» Guise TA, Mundy GR Disorders of calcium metabolism Therapy of Renal Diseases and Related Disorders, 3rd Edition, Suki WN, Massry SG (eds), Kluwer Academic Publishers, Boston, MA 1997. Chapter 5:85-114
» De La Mata J, Mundy GR Inflamacion y osteopenia en las enfermedades reumaticas Rev Esp Rheumatol 1997. 24:16-22
» Mundy GR Hypercalcemia of malignancy Metabolic Bone Disease, 3rd Edition, Avioli LV, Krane SM (eds) 1997. :637-649
» Mundy GR Bone remodeling and mehanisms of bone loss in osteoporosis Osteoporosis - State of the Art, Meunier P (ed), Martin Dunitz Publishers, London 1997. :17-35
» Lipton A, Mundy GR, Singer FR Introduction to skeletal complications of malignancy Cancer 1997. (Suppl 80/8):1527-1528
» Mundy GR, Yates AJ, Reasner CA Hypercalcemia of Malignancy Encyclopedia of Human Biology, 2nd Edition 1997. 4:653-660
» Dequeker J, Mundy GR Management of Osteoporosis Rheumatology: Management of Rheumatic Diseases, Klippel JH, Dieppe PA (eds) Brooks PM, Gerber LH (section eds), 2nd Edition, Mosty-Year Book Europe Limited, London 1997. 39:1-4
» Mundy, GR Mechanisms of bone metastasis Cancer 1997. 80:1546-56
» Mundy, GR, Guise, TA Hypercalcemia of malignancy Am J Med 1997. 103:134-45
» Uy, HL, Mundy, GR, Boyce, BF, Story, BM, Dunstan, CR, Yin, JJ, Roodman, GD, Guise, TA Tumor necrosis factor enhances parathyroid hormone-related protein-induced
hypercalcemia and bone resorption without inhibiting bone formation in vivo Cancer Res 1997. 57:3194-9
» Garrett, IR, Dallas, S, Radl, J, Mundy, GR A murine model of human myeloma bone disease Bone 1997. 20:515-20
» Yoneda, T, Sasaki, A, Dunstan, C, Williams, PJ, Bauss, F, De Clerck, YA, Mundy, GR Inhibition of osteolytic bone metastasis of breast cancer by combined treatment
with the bisphosphonate ibandronate and tissue inhibitor of the matrix metalloproteinase-2 J Clin Invest 1997. 99:2509-17
» Samuels, MH, Veldhuis, JD, Kramer, P, Urban, RJ, Bauer, R, Mundy, GR Episodic secretion of parathyroid hormone in postmenopausal women: assessment
by deconvolution analysis and approximate entropy J Bone Miner Res 1997. 12:616-23
» Mundy, GR Malignancy and the skeleton Horm Metab Res 1997. 29:120-7
» Feng, JQ, Chen, D, Ghosh-Choudhury, N, Esparza, J, Mundy, GR, Harris, SE Bone morphogenetic protein 2 transcripts in rapidly developing deer antler
tissue contain an extended 5'' non-coding region arising from a distal promoter Biochim Biophys Acta 1997. 1350:47-52
» Bonewald, LF, Flynn, M, Qiao, M, Dallas, MR, Mundy, GR, Boyce, BF Mice lacking 5-lipoxygenase have increased cortical bone thickness Adv Exp Med Biol 1997. 433:299-302
» Mundy, GR Growth factors as potential therapeutic agents in osteoporosis Instr Course Lect 1997. 46:495-8
» Chen, D, Harris, MA, Rossini, G, Dunstan, CR, Dallas, SL, Feng, JQ, Mundy, GR, Harris, SE Bone morphogenetic protein 2 (BMP-2) enhances BMP-3, BMP-4, and bone cell differentiation
marker gene expression during the induction of mineralized bone matrix formation in cultures of fetal
rat calvarial osteoblasts Calcif Tissue Int 1997. 60:283-90
» Ghosh-Choudhury, N, Harris, MA, Wozney, J, Mundy, GR, Harris, SE Clonal osteoblastic cell lines from p53 null mouse calvariae are immortalized
and dependent on bone morphogenetic protein 2 for mature osteoblastic phenotype Biochem Biophys Res Commun 1997. 231:196-202
» Izbicka, E, Dunstan, CR, Horn, D, Harris, M, Harris, S, Adams, R, Mundy, GR Effects of human tumor cell lines on local new bone formation in vivo Calcif Tissue Int 1997. 60:210-5
» Izbicka, E, Dunstan, CR, Horn, D, Adams, R, Mundy, GR Mitogenic lectin concanavalin A induces calvarial bone formation in vivo via
indomethacin-sensitive pathway Calcif Tissue Int 1997. 60:204-9
» Bonewald, LF, Oreffo, RO, Lee, CH, Park-Snyder, S, Twardzik, D, Mundy, GR Effects of retinol on activation of latent transforming growth factor-beta
by isolated osteoclasts Endocrinology 1997. 138:657-66
» Mundy GR, Lane NE Bone Agents Rheumatology: Management of Rheumatic Diseases, Klippel JH, Dieppe PA (eds) Brooks PM, Gerber LH (section eds), 2nd Edition, Mosby-Year Book Europe Limited, London 1997. 38:1-4
» Mundy GR Role of cytokines, parathyroid hormone, growth factors in malignancy Molecular Mechanisms of Metabolic Bone Diseases, Principles of Bone Biology, Bilezikian J, Raisz L, Rodan G (eds), Academic Press, San Diego, CA 1996. :827-836
» Parfitt, AM, Mundy, GR, Roodman, GD, Hughes, DE, Boyce, BF A new model for the regulation of bone resorption, with particular reference
to the effects of bisphosphonates J Bone Miner Res 1996. 11:150-9
» Mundy GR Disorders of serum minerals: Hypercalcemia in hematologic malignancies and in solid tumors associated with extensive localized bone destruction. Primer on the Metabolic Bone Disease and Disorder of Mineral Metabolism. Favus MJ (Ed.), 3rd edition, Raven Press 1996. :203-205
» Mundy GR, Yoneda T Mechanisms of bone metastasis Mechanisms and Pathophysiology of Bone Metastasis, Orr FW, Singh G (eds), R.G. Landes Company 1996. :1-16
» Trippel SB, Coutts RD, Einhorn TA, Mundy GR, Rosenfeld RG Growth factors as therapeutic agents J Bone Joint Surg 1996. 78:1272-1286
» Mundy GR Regulatory mechanisms of osteoclast differentiation and function J Bone Miner Metab 1996. 14:59-64
» Mundy GR Regulatory mechanisms of osteoclast differentiation and function Osteoporosis Japan 1996. 4:39-46
» Mundy, GR Regulation of bone formation by bone morphogenetic proteins and other growth
factors Clin Orthop Relat Res 1996. :24-8
» Izbicka, E, Dunstan, C, Esparza, J, Jacobs, C, Sabatini, M, Mundy, GR Human amniotic tumor that induces new bone formation in vivo produces growth-regulatory
activity in vitro for osteoblasts identified as an extended form of basic fibroblast growth factor Cancer Res 1996. 56:633-6
» Ghosh-Choudhury, N, Windle, JJ, Koop, BA, Harris, MA, Guerrero, DL, Wozney, JM, Mundy, GR, Harris, SE Immortalized murine osteoblasts derived from BMP 2-T-antigen expressing transgenic
mice Endocrinology 1996. 137:331-9
» Mundy GR Anatomy, physiology and functin of bone: Bone resorbing cells Primer on the Metabolic Bone Disease and Disorder of Mineral Metabolism. Favus MJ (ed.) 3rd edition, Raven Press 1996. :16-23
» Guise, TA, Yin, JJ, Taylor, SD, Kumagai, Y, Dallas, M, Boyce, BF, Yoneda, T, Mundy, GR Evidence for a causal role of parathyroid hormone-related protein in the pathogenesis
of human breast cancer-mediated osteolysis J Clin Invest 1996. 98:1544-9
» Izbicka, E, Yoneda, T, Takaoka, Y, Horn, D, Williams, P, Mundy, GR Identification of a novel bone/calcium metabolism-regulating factor in porcine
pancreas J Biol Chem 1996. 271:23230-4
» Mbalaviele, G, Dunstan, CR, Sasaki, A, Williams, PJ, Mundy, GR, Yoneda, T E-cadherin expression in human breast cancer cells suppresses the development
of osteolytic bone metastases in an experimental metastasis model Cancer Res 1996. 56:4063-70
» Guise, TA, Mundy, GR Physiological and pathological roles of parathyroid hormone-related peptide Curr Opin Nephrol Hypertens 1996. 5:307-15
» Moriyama, K, Williams, PJ, Niewolna, M, Dallas, MR, Uehara, Y, Mundy, GR, Yoneda, T Herbimycin A, a tyrosine kinase inhibitor, impairs hypercalcemia associated
with a human squamous cancer producing interleukin-6 in nude mice J Bone Miner Res 1996. 11:905-11
» Mundy, GR Osteoporosis into the year 2010 Br J Obstet Gynaecol 1996. 103 Suppl 13:32-7; discussion 37-8
» Garcia, C, Qiao, M, Chen, D, Kirchen, M, Gallwitz, W, Mundy, GR, Bonewald, LF Effects of synthetic peptido-leukotrienes on bone resorption in vitro J Bone Miner Res 1996. 11:521-9
» Mundy, GR An OAF by any other name Endocrinology 1996. 137:1149-50
» Garcia, C, Boyce, BF, Gilles, J, Dallas, M, Qiao, M, Mundy, GR, Bonewald, LF Leukotriene B4 stimulates osteoclastic bone resorption both in vitro and in
vivo J Bone Miner Res 1996. 11:1619-27
» Hughes, DE, Dai, A, Tiffee, JC, Li, HH, Mundy, GR, Boyce, BF Estrogen promotes apoptosis of murine osteoclasts mediated by TGF-beta Nat Med 1996. 2:1132-6
» Alsina, M, Boyce, B, Devlin, RD, Anderson, JL, Craig, F, Mundy, GR, Roodman, GD Development of an in vivo model of human multiple myeloma bone disease Blood 1996. 87:1495-501
» Mundy GR, Boyce BF, Yoneda T, Bonewald LF, Roodman GD Cytokines and bone remodeling Osteoporosis, Marcus B, Kelsey J, Feldman D (eds), Academic Press, New York 1996. Chapter 11:301-313
» Mundy GR Editorial Review Parathyroids and Bone and Mineral Metabolism, Current Opinion in Endocrinology and Diabetes 1995. 2:539-542
» Mundy GR Myeloma Bone Disease Myeloma Today 1995. 1:
» Mundy GR, Roodman GD, Yoneda T Role of cytokines in regulation of bone remodeling and osteoporosis Human Cytokines: Their Role in Health and Disease. Aggarwal B, Puri R (eds), Blackwell Scientific Publications, Inc. 1995. Chapter 17:285-292
» Guise TA, Mundy GR Breast cancer and bone Parathyroids and Bone and Mineral Metabolism, Current Opinion in Endocrinology and Diabetes 1995. 2:548-555
» Chen D, Chen H, Feng JQ, Windle JJ, Harris MA, Bonewald LF, Boyce GBF, Wozney JM, Mundy GR, Harris SE Osteoblastic cell lines derived from a transgenic mouse containing osteocalcin promoter driving SV40 T antigen Mol Cell Diff 1995. 3:193-212
» Harris SE, Feng JQ, Harris MA, Ghosh-Choudhury N, Dallas MR, Wozney J, Mundy GR Recombinant bone morphogenetic protein 2 accelerates bone cell differentiation and stimulates BMP2 mRNA expression and BMP2 promoter activity in primary fetal rat calvarial osteoblast cultures Mol Cell Diff 1995. 3:137-155
» Mundy GR The genetics of osteoporosis The Endocrinologist 1995. 5:176-179
» Self-organizing bone cell differentiation in vitro: A system in search of the "edge of chaos" Chaos and Complexity, Editions Frontieres, Thanh Van JR, Berge P, Conte R, Dubois M (eds), Cedex, France 1995. :239-245
» Yoneda T, Izbicka E, Feng J, Takoako Y, Mundy GR A novel bone/calcium metabolism-regulating factor in porcine pancreas Osteoporosis Jap 1995. 3:52-55
» Mundy GR, Reasner CA Hypocalcemia Principles and Practice of Nephrology. H. Jacobson, G. Striker, S. Klahr (eds.) 1995. 2nd Edition, Chapter 141:971-977
» Foreward In: Hypercalcemia of Malignancy: Etiology, Pathogenesis and Treatment Hypercalcemia of Malignancy: Etiology, Pathogenesis and Treatment. S.J. Wimalawansa, R.G. Landes, Austin, Texas 1995. :
» Chen, D, Feng, JQ, Feng, M, Harris, MA, Mahy, P, Mundy, GR, Harris, SE Sequence and expression of bone morphogenetic protein 3 mRNA in prolonged cultures
of fetal rat calvarial osteoblasts and in rat prostate adenocarcinoma PA III cells DNA Cell Biol 1995. 14:235-9
» Riancho, JA, Mundy, GR The role of cytokines and growth factors as mediators of the effects of systemic
hormones at the bone local level Crit Rev Eukaryot Gene Expr 1995. 5:193-217
» Mundy, GR No bones about fluoride Nat Med 1995. 1:1130-1
» Dallas, SL, Miyazono, K, Skerry, TM, Mundy, GR, Bonewald, LF Dual role for the latent transforming growth factor-beta binding protein in
storage of latent TGF-beta in the extracellular matrix and as a structural matrix protein J Cell Biol 1995. 131:539-49
» Mbalaviele, G, Chen, H, Boyce, BF, Mundy, GR, Yoneda, T The role of cadherin in the generation of multinucleated osteoclasts from mononuclear
precursors in murine marrow J Clin Invest 1995. 95:2757-65
» Guise, TA, Mundy, GR Clinical review 69: Evaluation of hypocalcemia in children and adults J Clin Endocrinol Metab 1995. 80:1473-8
» Mundy, GR, Yoneda, T Facilitation and suppression of bone metastasis Clin Orthop Relat Res 1995. :34-44
» Uy, HL, Dallas, M, Calland, JW, Boyce, BF, Mundy, GR, Roodman, GD Use of an in vivo model to determine the effects of interleukin-1 on cells
at different stages in the osteoclast lineage J Bone Miner Res 1995. 10:295-301
» Hughes, DE, Wright, KR, Uy, HL, Sasaki, A, Yoneda, T, Roodman, GD, Mundy, GR, Boyce, BF Bisphosphonates promote apoptosis in murine osteoclasts in vitro and in vivo J Bone Miner Res 1995. 10:1478-87
» Feng, JQ, Chen, D, Esparza, J, Harris, MA, Mundy, GR, Harris, SE Deer antler tissue contains two types of bone morphogenetic protein 4 mRNA
transcripts Biochim Biophys Acta 1995. 1263:163-8
» Sasaki, A, Boyce, BF, Story, B, Wright, KR, Chapman, M, Boyce, R, Mundy, GR, Yoneda, T Bisphosphonate risedronate reduces metastatic human breast cancer burden in
bone in nude mice Cancer Res 1995. 55:3551-7
» Mundy, GR, Boyce, B, Hughes, D, Wright, K, Bonewald, L, Dallas, S, Harris, S, Ghosh-Choudhury, N, Chen, D, Dunstan, C The effects of cytokines and growth factors on osteoblastic cells Bone 1995. 17:71S-75S
» Mundy GR Future Therapies for Osteoporosis Published in the Proceedings of the Second International Symposium on Osteoporosis, Beijing, P.R. China 1995. :
» Feng, JQ, Chen, D, Cooney, AJ, Tsai, MJ, Harris, MA, Tsai, SY, Feng, M, Mundy, GR, Harris, SE The mouse bone morphogenetic protein-4 gene. Analysis of promoter utilization
in fetal rat calvarial osteoblasts and regulation by COUP-TFI orphan receptor J Biol Chem 1995. 270:28364-73
» Alsina, M, Boyce, BF, Mundy, GR, Roodman, GD An in vivo model of human multiple myeloma bone disease Stem Cells 1995. 13 Suppl 2:48-50
» Uy, HL, Guise, TA, De La Mata, J, Taylor, SD, Story, BM, Dallas, MR, Boyce, BF, Mundy, GR, Roodman, GD Effects of parathyroid hormone (PTH)-related protein and PTH on osteoclasts
and osteoclast precursors in vivo Endocrinology 1995. 136:3207-12
» de la Mata, J, Uy, HL, Guise, TA, Story, B, Boyce, BF, Mundy, GR, Roodman, GD Interleukin-6 enhances hypercalcemia and bone resorption mediated by parathyroid
hormone-related protein in vivo J Clin Invest 1995. 95:2846-52
» Yoneda, T, Williams, P, Rhine, C, Boyce, BF, Dunstan, C, Mundy, GR Suramin suppresses hypercalcemia and osteoclastic bone resorption in nude mice
bearing a human squamous cancer Cancer Res 1995. 55:1989-93
» Mundy, GR Local control of bone formation by osteoblasts Clin Orthop Relat Res 1995. :19-26
» Mundy GR, Reasner CA Hypercalcemia Principles and Practice of Nephrology. H. Jacobson, G. Striker, S. Klahr (eds.) 1995. 2nd Edition, Chapter 142:977-986
» Izbicka E, Niewolna M, Yoneda T, Lowe C, Boyce B, Mundy G pp60c-src expression and activity in MG-63 osteoblastic cells is modulated by PTH, but is not required for PTH-mediated adenylate cyclase response J Bone Miner Res 1994. 9:127-132
» Mundy GR Calcium and common endocring bone disorders Clinical Endocrinology 2E. Besser M, Thorner M (eds), Gower Medical Publishing, Ciba 1994. Chapter 18:18.1-18.16
» Mundy GR, Reasner CA Osteopetrosis Internal Medicine, J.H. Stein (ed.), Mosby Publishers 1994. 4th edition, chapter 184:1532-1534
» Mundy GR Bone remodeling and its disorders Martin Dunitz, London 1994. 1st Edition:
» Mundy GR Ask Drug Therapy - A Question-and-Answer Seminar with the Drug Therapy Experts: Which drugs are now used for severe osteoporosis? Drug Therapy 1994. 24:23
» Mundy GR New drugs for bone diseases Drugs of Today 1994. 30:589-597
» Mundy GR, Reasner CA Fibrous dysplasia Internal Medicine, J.H. Stein (ed.), Mosby Publishers 1994. 4th Edition, Chapter 185:1534-1536
» Mundy GR, Reasner CA Diagnostic Approach to Bone and Mineral Disorders Internal Medicine, J.H. Stein, (ed.), Mosby Publishers 1994. 4th Edition, Chapter 151:1254-1260
» Mundy GR, Reasner CA Physiology of Bone and Mineral Homeostasis Internal Medicine, J.H. Stein, (ed.) 4th edition, Mosby Publishers 1994. Chapter 148:1214-1222
» Black KS, Mundy GR Other causes of hypercalcemia; local and ectopic secretion syndromes. The Parathyroids: Basic & Clinical Concepts, bilezikian JP, Marcus R, Levine MA (eds), Raven Press 1994. Chapter 21:341-357
» What role for etidronate in bone pain from prostate cancer? Cancer Consultations 1994. 1:162
» Mundy GR The regulatory mechanisms responsible for osteoclastic bone resorption and control of the osteoclast life cycle. Published in the 3rd International Forum on Calcified Tissue and Bone Metabolism [Bone Cell Function: Cell-Cell/Cell-Matrix Interactions]. International Bone Forum, Yokohama, Japan 1994. :40-45
» Mundy, GR Peptides and growth regulatory factors in bone Rheum Dis Clin North Am 1994. 20:577-88
» Feng, JQ, Harris, MA, Ghosh-Choudhury, N, Feng, M, Mundy, GR, Harris, SE Structure and sequence of mouse bone morphogenetic protein-2 gene (BMP-2):
comparison of the structures and promoter regions of BMP-2 and BMP-4 genes Biochim Biophys Acta 1994. 1218:221-4
» Harris, SE, Harris, MA, Mahy, P, Wozney, J, Feng, JQ, Mundy, GR Expression of bone morphogenetic protein messenger RNAs by normal rat and human
prostate and prostate cancer cells Prostate 1994. 24:204-11
» Dallas, SL, Park-Snyder, S, Miyazono, K, Twardzik, D, Mundy, GR, Bonewald, LF Characterization and autoregulation of latent transforming growth factor beta
(TGF beta) complexes in osteoblast-like cell lines. Production of a latent complex lacking the latent
TGF beta-binding protein J Biol Chem 1994. 269:6815-21
» Nishihara, T, Ohsaki, Y, Ueda, N, Saito, N, Mundy, GR Mouse interleukin-1 receptor antagonist induced by Actinobacillus actinomycetemcomitans
lipopolysaccharide blocks the effects of interleukin-1 on bone resorption and osteoclast-like cell formation Infect Immun 1994. 62:390-7
» Mundy, GR Osteoporosis. Boning up on genes Nature 1994. 367:216-7
» Ghosh-Choudhury, N, Harris, MA, Feng, JQ, Mundy, GR, Harris, SE Expression of the BMP 2 gene during bone cell differentiation Crit Rev Eukaryot Gene Expr 1994. 4:345-55
» Mundy, GR Evaluation and treatment of hypercalcemia Hosp Pract (Off Ed) 1994. 29:79-84; discussion 84-6
» Harris, SE, Bonewald, LF, Harris, MA, Sabatini, M, Dallas, S, Feng, JQ, Ghosh-Choudhury, N, Wozney, J, Mundy, GR Effects of transforming growth factor beta on bone nodule formation and expression
of bone morphogenetic protein 2, osteocalcin, osteopontin, alkaline phosphatase, and type I collagen
mRNA in long-term cultures of fetal rat calvarial osteoblasts J Bone Miner Res 1994. 9:855-63
» Yoneda, T, Takaoka, Y, Boyce, BF, Scott, L, Mundy, GR Extracts of porcine pancreas prevent progression of hypercalcemia and cachexia
and prolong survival in nude mice bearing a human squamous carcinoma Cancer Res 1994. 54:2509-13
» Harris, SE, Sabatini, M, Harris, MA, Feng, JQ, Wozney, J, Mundy, GR Expression of bone morphogenetic protein messenger RNA in prolonged cultures
of fetal rat calvarial cells J Bone Miner Res 1994. 9:389-94
» Yoneda, T, Sasaki, A, Mundy, GR Osteolytic bone metastasis in breast cancer Breast Cancer Res Treat 1994. 32:73-84
» Mundy GR Bone Agents Rheumatology: Management of Rheumatic Diseases, Klippel JH, Dieppe PA (eds) Brooks PM, Gerber LH (section eds), Mosby-Year Book Europe Limited, London 1994. Section 8, Chapter 17:17.1-17.6
» Mundy GR, Reasner CA Malignant Disease and the Skeleton Internal Medicine, J.H. Stein, (ed.), Mosby Publishers 1994. 4th Edition, Chapter 188:1548-1552
» Mundy GR, Harris SE, Sabatini M, Gutierrez G, Garrett IR, Izbicka E The use of osteosarcoma cells to characterize factors which regulate bone cell function Frontiers of Osteosarcoma Research, Novak JF, McMaster JH (eds), Hogrefe & Huber Publishers, Seattle, WA 1993. :449-456
» Chen, D, Feng, JQ, Feng, M, Harris, MA, Mundy, GR, Harris, SE Cloning and sequence of bone morphogenetic protein 4 cDNA from fetal rat calvarial
cell Biochim Biophys Acta 1993. 1174:289-92
» Mundy GR The Musculoskeletal System C. Bone. Primer on Rheumatic Diseases, Schumacher HR, Klippel J, Koppman W (eds), Arthritis Foundation, Atlanta, GA, 10th edition 1993. :11-14
» Mundy GR Anatomy, physiology and function of bone: Bone resorbing cells Primer on the Metabolic Bone Disease and Disorder of Mineral Metabolism, Favus MJ (ed.), Raven Press 1993. 2nd edition, Chapter 5:25-33
» Mundy GR Parathyroids and bone and mineral metabolism: editorial overview Current Opinion in Endocrinology and Diabetes, Kohler PO (ed), Current Science, Philadelphia, PA 1993. :267-269
» Mundy GR Disorders of serum minerals: Hypercalcemia in hematologic malignancies and in solid tumors associated with extensive localized bone destruction Primer on the Metabolic Bone Disease and Disorder of Mineral Metabolism 1993. Chapter 34:173-176
» Samuels JH, Veldhuis J, Cawley C, Urban RJ, Luther M, Bauer R, Mundy G Pulsatile secretion of parathyroid hormone in normal young subjects: Assessment by deconvolution analysis J Clin Endo 1993. 77:399-403
» Mundy GR Basic science in osteoporosis. Osteoclast model systems Proceedings of the Fourth International Symposium on Osteoporosis. C. Christiansen, B. Riis (eds) 1993. :254-257
» Mundy GR Basic science in osteoporosis. Osteoclast model systems. Proceedings of the Fourth International Symposium on Osteoporosis. C. Christiansen, B. Riis (eds) 1993. :254-257
» Mundy GR Osteoporosis today and tomorrow. Bone growth factors for osteoporosis - A realizable dream? Proceedings of the Fourth International Symposium on Osteoporosis 1993. :414-417
» Mundy GR Bone Primer on Rheumatic Diseases. 10th Edition. H.R. Schumacher, (ed). 1/-14 1993. :
» Osteoblast function and the mechanism of action of bone forming agents Osteoporosis 1996. Proceedings of the 1996 World Congress on Osteoporosis, Amsterdam, The Netherlands 1993. :17-28
» Guise, TA, Yoneda, T, Yates, AJ, Mundy, GR The combined effect of tumor-produced parathyroid hormone-related protein and
transforming growth factor-alpha enhance hypercalcemia in vivo and bone resorption in vitro J Clin Endocrinol Metab 1993. 77:40-5
» Mundy, GR Role of cytokines in bone resorption J Cell Biochem 1993. 53:296-300
» Garrett, IR, Guise, TA, Bonewald, LF, Chizzonite, R, Mundy, GR Evidence that interleukin-1 mediates its effects on bone resorption via the
80 kilodalton interleukin-1 receptor Calcif Tissue Int 1993. 52:438-41
» Guise, TA, Garrett, IR, Bonewald, LF, Mundy, GR Interleukin-1 receptor antagonist inhibits the hypercalcemia mediated by interleukin-1 J Bone Miner Res 1993. 8:583-7
» Mundy, GR Visions for the future in osteoporosis research Osteoporos Int 1993. 3 Suppl 2:S29-34
» Mundy, GR Local control of osteoclast function Osteoporos Int 1993. 3 Suppl 1:126-7
» Yoneda, T, Lowe, C, Lee, CH, Gutierrez, G, Niewolna, M, Williams, PJ, Izbicka, E, Uehara, Y, Mundy, GR Herbimycin A, a pp60c-src tyrosine kinase inhibitor, inhibits osteoclastic
bone resorption in vitro and hypercalcemia in vivo J Clin Invest 1993. 91:2791-5
» Mundy, GR Factors which stimulate bone growth in vivo Growth Regul 1993. 3:124-8
» Gallwitz, WE, Mundy, GR, Lee, CH, Qiao, M, Roodman, GD, Raftery, M, Gaskell, SJ, Bonewald, LF 5-Lipoxygenase metabolites of arachidonic acid stimulate isolated osteoclasts
to resorb calcified matrices J Biol Chem 1993. 268:10087-94
» Lowe, C, Yoneda, T, Boyce, BF, Chen, H, Mundy, GR, Soriano, P Osteopetrosis in Src-deficient mice is due to an autonomous defect of osteoclasts Proc Natl Acad Sci U S A 1993. 90:4485-9
» Boyce, BF, Chen, H, Soriano, P, Mundy, GR Histomorphometric and immunocytochemical studies of src-related osteopetrosis Bone 1993. 14:335-40
» Yoneda, T, Nakai, M, Moriyama, K, Scott, L, Ida, N, Kunitomo, T, Mundy, GR Neutralizing antibodies to human interleukin 6 reverse hypercalcemia associated
with a human squamous carcinoma Cancer Res 1993. 53:737-40
» Guise TA, Mundy GR Bones and cancer Endocrine Rev 1993. 14:255
» Mundy, GR Hypercalcemia of malignancy Clinical Oncology. Weiss G. (ed), Lange Medical Publications 1993. :380-384
» Mundy GR Hypercalcemia associated with malignant tumors. Endocrine Tumors. Mazzaferri E, Samaan N (eds), Blackwell Scientific Publications, London, England 1993. Chapter 36:567-691
» Mundy GR Cytokines and bone remodeling Clinical Applications of Cytokines: Role in Pathogenesis, Diagnosis and Therapy. Oppenheim JJ, Gearing AJ, Rossi JL (eds), Oxford University Press, New York, NY 1993. Chapter 44:347-356
» Mundy GR Cytokines of Bone Physiology and Pharmacology of Bone. Handbook of Experimental Pharmacology 1993. Chapter 5:185-214
» Mundy GR, Martin TJ Pathophysiology of Skeletal Complications of Cancer Physiology and Pharmacology of Bone. Handbook of Experimental Pharmacology. Mundy GR, Martin TJ (eds), Springer, Berlin, Germany 1993. Chapter 18:641-671
» Mundy GR Hormonal Factors which Regulate Bone Resorption Physiology and Pharmacology of Bone. Handbook of Experimental Pharmacology. Mundy GR, Martin TJ (eds), Springer, Berlin, Germany 1993. Chapter 6:215-247
» Mundy GR Future therapies for osteoporosis Comprehensive Management of Menopause. Lorrain J, Plouffe L, Ravnikar V, Speroff L, Watts N (eds), Springer-Verlag 1993. Chapter 40:425-433
» Mundy, GR Cytokines and growth factors in the regulation of bone remodeling J Bone Miner Res 1993. 8 Suppl 2:S505-10
» Riancho, JA, Zarrabeitia, MT, Mundy, GR, Yoneda, T, Gonz?!lez-Mac?-as, J Effects of interleukin-4 on the formation of macrophages and osteoclast-like
cells J Bone Miner Res 1993. 8:1337-44
» Yoneda, T, Kato, I, Bonewald, LF, Burgess, WH, Mundy, GR A novel cytokine with osteoclastopoietic activity J Periodontal Res 1993. 28:521-2
» Oreffo, RO, Marshall, GJ, Kirchen, M, Garcia, C, Gallwitz, WE, Chavez, J, Mundy, GR, Bonewald, LF Characterization of a cell line derived from a human giant cell tumor that
stimulates osteoclastic bone resorption Clin Orthop Relat Res 1993. :229-41
» Reasner, CA, Stone, MD, Hosking, DJ, Ballah, A, Mundy, GR Acute changes in calcium homeostasis during treatment of primary hyperparathyroidism
with risedronate J Clin Endocrinol Metab 1993. 77:1067-71
» Yoneda, T, Niewolna, M, Lowe, C, Izbicka, E, Mundy, GR Hormonal regulation of pp60c-src expression during osteoclast formation in
vitro Mol Endocrinol 1993. 7:1313-8
» Mundy GR, Boyce BF, Yoneda T Mechanisms of osteolytic bone destruction Metastatic Bone Disease. Fundamental and Clinical Aspects. Diel IJ, Kaufmann M, Bastert G (eds), Springer Verlag, Heidelberg 1993. :86-92
» Mundy GR Factores locales en el control de la reabsorcion y formacion de hueso Actualizaciones en Metabolismo Oseo: Aspectos basicos sobre metaboismo oseo. (Presented at the Spanish Society of Bone and Mineral Meeting in Oviedo, Spain 1991), Cannata Andia JB (ed), Jarpyo Editores, Madrid, Spain 1992. :
» Gutierrez G, Mundy GR Cytokines of bone Revista Espanola de Enfermedades Metabolicas Oseas, Rapado A (ed.) 1992. 1 (4):100-103
» Yates, AJ, Boyce, BF, Favarato, G, Aufdemorte, TB, Marcelli, C, Kester, MB, Walker, R, Langton, BC, Bonewald, LF, Mundy, GR Expression of human transforming growth factor alpha by Chinese hamster ovarian
tumors in nude mice causes hypercalcemia and increased osteoclastic bone resorption J Bone Miner Res 1992. 7:847-53
» Mundy, GR, Roodman, GD, Bonewald, LF, Yoneda, T, Sabatini, M Effects of TNF and lymphotoxin on bone cells Immunol Ser 1992. 56:483-98
» Guise, TA, Chirgwin, JM, Favarato, G, Boyce, BF, Mundy, GR Chinese hamster ovarian cells transfected with human parathyroid hormone-related
protein cDNA cause hypercalcemia in nude mice Lab Invest 1992. 67:477-85
» Nakai, M, Mundy, GR, Williams, PJ, Boyce, B, Yoneda, T A synthetic antagonist to laminin inhibits the formation of osteolytic metastases
by human melanoma cells in nude mice Cancer Res 1992. 52:5395-9
» Mundy GR Local factors regulating osteoclast function The Biology and Physiology of the Osteoclast. Rifkin BR, Gay CV (eds), CRC Press 1992. Chapter 8:171-185
» Mundy, GR Cytokines and local factors which affect osteoclast function Int J Cell Cloning 1992. 10:215-22
» Boyce, BF, Yoneda, T, Lowe, C, Soriano, P, Mundy, GR Requirement of pp60c-src expression for osteoclasts to form ruffled borders
and resorb bone in mice J Clin Invest 1992. 90:1622-7
» Reddy, KB, Mangold, GL, Tandon, AK, Yoneda, T, Mundy, GR, Zilberstein, A, Osborne, CK Inhibition of breast cancer cell growth in vitro by a tyrosine kinase inhibitor Cancer Res 1992. 52:3636-41
» Mundy GR Mononuclear Phagocytes in Bone Cell Function Mononuclear Phagocytes Cell Biology. Lopez-Berestein G, Klostergaard J (eds), CRC Press, Inc. 1992. Chapter 5:101-117
» Mundy GR, Bonewald LF Transforming Growth Factor β Cytokines and Bone Metabolism. Russell RG and Gowen M (eds), CRC Press, Inc. 1992. Chapter 3:93-107
» Mundy GR Effects of TNF on bone and cartilage Tumor Necrosis Factors: The Molecules and Their Emerging Role in Medicine. Beutler B (ed), Raven Press, New York 1992. Chapter 8:107-116
» Katz, MS, Gutierrez, GE, Mundy, GR, Hymer, TK, Caulfield, MP, McKee, RL Tumor necrosis factor and interleukin 1 inhibit parathyroid hormone-responsive
adenylate cyclase in clonal osteoblast-like cells by down-regulating parathyroid hormone receptors J Cell Physiol 1992. 153:206-13
» Reasner, CA, Mundy, GR Diagnosis and treatment of osteoporosis Compr Ther 1991. 17:14-9
» Bonewald, LF, Wakefield, L, Oreffo, RO, Escobedo, A, Twardzik, DR, Mundy, GR Latent forms of transforming growth factor-beta (TGF beta) derived from bone
cultures: identification of a naturally occurring 100-kDa complex with similarity to recombinant latent
TGF beta Mol Endocrinol 1991. 5:741-51
» Yates, AJ, Oreffo, RO, Mayor, K, Mundy, GR Inhibition of bone resorption by inorganic phosphate is mediated by both reduced
osteoclast formation and decreased activity of mature osteoclasts J Bone Miner Res 1991. 6:473-8
» Black, K, Garrett, IR, Mundy, GR Chinese hamster ovarian cells transfected with the murine interleukin-6 gene
cause hypercalcemia as well as cachexia, leukocytosis and thrombocytosis in tumor-bearing nude mice Endocrinology 1991. 128:2657-9
» Yoneda, T, Alsina, MM, Watatani, K, Bellot, F, Schlessinger, J, Mundy, GR Dependence of a human squamous carcinoma and associated paraneoplastic syndromes
on the epidermal growth factor receptor pathway in nude mice Cancer Res 1991. 51:2438-43
» Mundy, GR Inflammatory mediators and the destruction of bone J Periodontal Res 1991. 26:213-7
» Yoneda, T, Aufdemorte, TB, Nishimura, R, Nishikawa, N, Sakuda, M, Alsina, MM, Chavez, JB, Mundy, GR Occurrence of hypercalcemia and leukocytosis with cachexia in a human squamous
cell carcinoma of the maxilla in athymic nude mice: a novel experimental model of three concomitant paraneoplastic
syndromes J Clin Oncol 1991. 9:468-77
» Yoneda, T, Alsina, MA, Chavez, JB, Bonewald, L, Nishimura, R, Mundy, GR Evidence that tumor necrosis factor plays a pathogenetic role in the paraneoplastic
syndromes of cachexia, hypercalcemia, and leukocytosis in a human tumor in nude mice J Clin Invest 1991. 87:977-85
» Mundy, GR Mechanisms of osteolytic bone destruction Bone 1991. 12 Suppl 1:S1-6
» Yoneda, T, Lyall, RM, Alsina, MM, Persons, PE, Spada, AP, Levitzki, A, Zilberstein, A, Mundy, GR The antiproliferative effects of tyrosine kinase inhibitors tyrphostins on
a human squamous cell carcinoma in vitro and in nude mice Cancer Res 1991. 51:4430-5
» Tuttle, KR, Kunau, RT, Loveridge, N, Mundy, GR Altered renal calcium handling in hypercalcemia of malignancy J Am Soc Nephrol 1991. 2:191-9
» Mundy, GR Can the triple threat survive biotech Am J Med Sci 1991. 302:38-41
» Mundy, GR Is prolonged stimulation of bone growth a therapeutic possibility Mol Cell Endocrinol 1991. 75:C19-25
» Yoneda, T, Takaoka, Y, Alsina, MM, Garcia, J, Mundy, GR Porcine pancreas extract decreases blood-ionized calcium in mice and inhibits
osteoclast formation and bone resorption in culture FEBS Lett 1991. 278:171-4
» Mundy, GR The effects of TGF-beta on bone Ciba Found Symp 1991. 157:137-43; discussion 143-51
» Mundy, GR New concepts in bone metabolism: clinical implications Hosp Pract (Off Ed) 1991. 26 Suppl 1:7-12
» Mundy, GR, Roodman, GD, Bonewald, LF, Oreffo, RO, Boyce, BF Assays for bone resorption and bone formation Methods Enzymol 1991. 198:502-10
» Mundy, GR Ectopic production of calciotropic peptides Endocrinol Metab Clin North Am 1991. 20:473-87
» Yoneda, T, Alsina, MM, Garcia, JL, Mundy, GR Differentiation of HL-60 cells into cells with the osteoclast phenotype Endocrinology 1991. 129:683-9
» Mundy Gr, Yates AJP, Reasner CA Hypercalcemia of malignancy Encyclopedia of Human Biology 1991. 4:275-282
» Black K, Reasner C, Mundy GR Endocrine paraneoplastic syndromes Current Diagnosis 8. Conn RB (ed). W.B. Saunders Co., Philadelphia 1991. :881-885
» Mundy GR Mechanisms of osteolysis and hypercalcemia in breast cancer Medical Management of Breast Cancer. Powles TJ, Smith IE (eds), Martin Dunitz Publishers 1991. Chapter 4:27-38
» Mundy GR Cytokines and bone remodeling J Bone Miner Metab 1991. 9:34-38
» Reasner C, Mundy GR The pathogenesis of hypercalcemia of malignancy Oncology Update 1991. Winter 1990/1991:7-9
» Windeler AS, Bonewald LF, Khara AG, Boyan BD, Mundy GR The influence of sputtered bone substitutes on cell growth and phenotypic expression The Bone-Biomaterial Interface. Davise JE (ed), University of Toronto Press 1991. :205-213
» Mundy GR Mechanisms of bone disease in multiple myeloma Monoclonal Gammapathies III-Clinical Significance and Basic Mechanisms, Radl J, Van Camp B (eds). Proceedings of the Third EURAGE Symposium, Brussels 1991. :51-56
» Mundy GR, Yates AJP, Reasner CA Hypercalcemia of malignancy Encyclopedia of Human Biology, 2nd Edition, Academic Press 1991. :275-282
» Mundy, GR Malignant Disease and the Skeleton Internal Medicine, J.H. Stein, (ed.), Little Brown 1990. Chapter 361:2379-2382
» Mundy, GR Incidence and pathophysiology of hypercalcemia Calcif Tissue Int 1990. 46 Suppl:S3-10
» Mundy GR, Roodman GD, Yoneda T, Bonewald L, Oreffo R Growth regulatory factors and bone cell function Calcium Regulation and Bone Metabolism. Basic and clinical aspects. Cohn DV, Glorieux FH, Martin TJ (eds.), Excerpta Medica, Amsterdam 1990. 10:257-269
» Mundy GR Commentary on "Management of hypercalcemia in breast cancer" by Richard Theriault, DO Oncology 1990. 4:50
» Mundy GR Dianostic Approach to Bone and Mineral Disorders Internal Medicine, J.H. Stein, (ed.), 3rd edition, Little Brown 1990. Chapter 324:22103-2108
» Mundy, GR Osteopetrosis Internal Medicine, J.H. Stein, (ed.) 3rd edition, Little Brown 1990. Chapter 357:2364-2366
» Mundy, GR Fibrous dysplasia Internal Medicine, J.H. Stein, (ed.) 3rd edition, Little Brown 1990. Chapter 358:2366-2367
» Mundy GR, Reasner C. Hypocalcemia Principles and Practice of Nephrology, H. Jacobson, G. Striker, S. Klahr (eds.) 1990. Chapter 18:104-109
» Mundy GR, Reasner C Hypercalcemia Principles and Practice of Nephrology, H. Jacobson, G. Striker, S. Klahr (eds.) 1990. Chapter 18:110-118
» Wo Z, Bonewald LF, Oreffo ROC, Chirgwin JM, Capony F, Rochefort H, Mundy GR The potential role of procathepsin D secreted by breast cancer cells in bone resorption Calcium Regulation and Bone Metabolism. Basic and clinical aspects. Cohn DV, Glorieux FH, Martin TJ (eds.), Excerpta Medica, Amsterdam 1990. 10:304-310
» Kukita A, Chenu C, McManus L, Mundy GR, Roodman GD Abnormal osteoclast-like cells form in Pagetic marrow cultures Calcium Regulation and Bone Metabolism. Basic and clinical aspects. Cohn DV, Glorieux FH, Martin TJ (eds), Excerpta Medica, Amsterdam 1990. 10:430-433
» Mundy GR Immune system and bone remodeling Trends in Endocrinology & Metabolism 1990. 1:307-311
» Calcium Homeostasis: Hypercalcemia and Hypocalcemia Calcium Homeostasis: Hypercalcemia and Hypocalcemia, 2nd Edition. Martin Dunitz, Longon 1990. :
» Mundy GR Bone cell function Effects of NSAIDS on Bone and Joint Disease: New Insights 1990. :81-84
» Mundy GR Pathophysiology of cancer-associated hypercalcemia Seminars in Oncology 1990. 17:10-16
» Mundy GR The Challenge of New Therapeutic Modalities: Osteoporosis into the 1990s - Outlook for growth factors into the 1990s Osteoporosis 1990. Christiansen C, Overgaard K (eds) 1990. 3:1953-1957
» Yoneda T, Mundy GR, Roodman GD Induction of differentation of the human promyelocytic HL-60 cells into cells with the osteoclastic phenotype Calcium Regulation and Bone Metabolism. Basic and clinical aspects. Cohn DV, Glorieux FH, Martin TJ (eds), Excerpta Medica, Amsterdam 1990. 10:425-429
» Mundy GR Regulation of bone growth and remodeling: Regulation of bone resorption Osteoporosis. Christiansen C, Overgaard K (eds) 1990. 1:248-252
» Mundy GR Current approaches to treatment of hypercalcemia of malignancy International Consensus of Supportive Care in Oncology 1990. 3:6-8
» Mundy GR Current concepts in bone biology and prospects for pharmacological intervention Bisphonates: Current Status and Future Prospects. IBC Conference, London, Russell RGG (ed) 1990. :
» Mundy, GR Disorders of serum minerals: Hypercalcemia in hematologic malignancies and in solid tumors associated with extensive localized bone desctruction Primer on the Metabolic Bone Disease and Disorder of Mineral Metabolism. Favus MJ (Ed.) 1990. Chapter 31:115-120
» Mundy, GR Anatomy, physiology and function of bone: Bone resorbing cells Primer on the Metabolic Bone Disease and Disorder of Mineral Metabolism. Favus MJ (Ed.) 1990. Chapter 5:18-22
» Pfeilschifter J, Bonewald L, Mundy GR The Role of Growth Factors in Cartilage and Bone Metabolism Handbook of Experimental Pharmacology: Peptide Growth Factors and their Receptors, M. Sporn and A. B. Roberts (eds.), Springer Verlag, Heidelberg 1990. 95, Chapter 33:371-400
» Mundy GR Physiology of Bone and Mineral Homeostasis Internal Medicine, J.H. Stein (ed), 3rd edition, Little Brown 1990. Chapter 321:2064-2071
» Sabatini, M, Yates, AJ, Garrett, IR, Chavez, J, Dunn, JF, Bonewald, L, Mundy, GR Increased production of tumor necrosis factor by normal immune cells in a model
of the humoral hypercalcemia of malignancy Lab Invest 1990. 63:676-82
» Marcelli, C, Yates, AJ, Mundy, GR In vivo effects of human recombinant transforming growth factor beta on bone
turnover in normal mice J Bone Miner Res 1990. 5:1087-96
» Gutierrez, GE, Mundy, GR, Manning, DR, Hewlett, EL, Katz, MS Transforming growth factor beta enhances parathyroid hormone stimulation of
adenylate cyclase in clonal osteoblast-like cells J Cell Physiol 1990. 144:438-47
» Pfeilschifter, J, Wolf, O, Naumann, A, Minne, HW, Mundy, GR, Ziegler, R Chemotactic response of osteoblastlike cells to transforming growth factor
beta J Bone Miner Res 1990. 5:825-30
» Flescher, E, Garrett, IR, Mundy, GR, Talal, N Induction of bone resorbing activity by normal and rheumatoid arthritis T cells Clin Immunol Immunopathol 1990. 56:210-8
» Chenu, C, Kurihara, N, Mundy, GR, Roodman, GD Prostaglandin E2 inhibits formation of osteoclastlike cells in long-term human
marrow cultures but is not a mediator of the inhibitory effects of transforming growth factor beta J Bone Miner Res 1990. 5:677-81
» Yates, AJ, Gutierrez, GE, Garrett, IR, Mencel, JJ, Nuss, GW, Schreiber, AB, Mundy, GR A noncyclical analog of salmon calcitonin (N alpha-propionyl Di-Ala1,7,des-Leu19
sCT) retains full potency without inducing anorexia in rats Endocrinology 1990. 126:2845-9
» Mundy, GR Presentation of the Southern Society for Clinical Investigation Founder''s Medal
to Dr. Jay H. Stein Am J Med Sci 1990. 299:372-3
» Oreffo, RO, Bonewald, L, Kukita, A, Garrett, IR, Seyedin, SM, Rosen, D, Mundy, GR Inhibitory effects of the bone-derived growth factors osteoinductive factor
and transforming growth factor-beta on isolated osteoclasts Endocrinology 1990. 126:3069-75
» Sabatini, M, Chavez, J, Mundy, GR, Bonewald, LF Stimulation of tumor necrosis factor release from monocytic cells by the A375
human melanoma via granulocyte-macrophage colony-stimulating factor Cancer Res 1990. 50:2673-8
» Kukita, A, Bonewald, L, Rosen, D, Seyedin, S, Mundy, GR, Roodman, GD Osteoinductive factor inhibits formation of human osteoclast-like cells Proc Natl Acad Sci U S A 1990. 87:3023-6
» Mundy, GR Pathophysiology of cancer-associated hypercalcemia Semin Oncol 1990. 17:10-5
» Garrett, IR, Boyce, BF, Oreffo, RO, Bonewald, L, Poser, J, Mundy, GR Oxygen-derived free radicals stimulate osteoclastic bone resorption in rodent
bone in vitro and in vivo J Clin Invest 1990. 85:632-9
» Reasner, CA, Dunn, JF, Fetchick, DA, Liel, Y, Hollis, BW, Epstein, S, Shary, J, Mundy, GR, Bell, NH Alteration of vitamin D metabolism in Mexican-Americans J Bone Miner Res 1990. 5:13-7
» Kukita, A, Chenu, C, McManus, LM, Mundy, GR, Roodman, GD Atypical multinucleated cells form in long-term marrow cultures from patients
with Paget''s disease J Clin Invest 1990. 85:1280-6
» Gutierrez, GE, Poser, JW, Katz, MS, Yates, AJ, Henry, HL, Mundy, GR Mechanisms of hypercalcaemia of malignancy Baillieres Clin Endocrinol Metab 1990. 4:119-38
» Reasner, CA, Yates, AJ, Mundy, GR Parathyroid gland disease and hypercalcemia Curr Opin Rheumatol 1990. 2:20-5
» Bonewald, LF, Mundy, GR Role of transforming growth factor-beta in bone remodeling Clin Orthop Relat Res 1990. :261-76
» Pfeilschifter, J, Bonewald, L, Mundy, GR Characterization of the latent transforming growth factor beta complex in bone J Bone Miner Res 1990. 5:49-58
» Mundy, GR, Bonewald, LF Role of TGF beta in bone remodeling Ann N Y Acad Sci 1990. 593:91-7
» Mundy GR, Reasner C Calcium Metabolism H. Jacobson, G. Striker, S. Klahr (Eds.) Principles and Practice of Nephrology. 1990. Chapter 16:98-103
» Mundy, GR Calcium homeostasis: Hypercalcemia and Hypocalcemia M. Dunitz, London 1989. :
» Mundy GR Pathophysiology of Hypercalcemia of Malignancy Endocrine and Non-endocrine Hormone-Producing Tumors. Proceedings of 33rd Annual Clinical Conference - M.D. Anderson Cancer Center 1989. :
» Takahashi, N, Kukita, T, MacDonald, BR, Bird, A, Mundy, GR, McManus, LM, Miller, M, Boyde, A, Jones, SJ, Roodman, GD Osteoclast-like cells form in long-term human bone marrow but not in peripheral
blood cultures J Clin Invest 1989. 83:543-50
» Pfeilschifter, J, Chenu, C, Bird, A, Mundy, GR, Roodman, GD Interleukin-1 and tumor necrosis factor stimulate the formation of human osteoclastlike
cells in vitro J Bone Miner Res 1989. 4:113-8
» Graves DT, Valentin-Opran A, Delgado R, Valente AJ, Mundy GR, Piche J The potential role of platelet-derived growth factors as an autocrine or paracrine factor for human bone cells Conn Tiss Res 1989. 23:209-218
» Mundy GR Identifying mechanisms for increasing bone mass J NIH Res 1989. 1:65-68
» Mundy GR Pathophysiological aspects of tumour-induced hypercalcaemia and bone metastases Disodium pamidronate (APD) in the treatment of malignancy-related disorders. Burckhardt P (ed.), Hans Hyber Publishers 1989. :12-20
» Oreffo, RO, Mundy, GR, Seyedin, SM, Bonewald, LF Activation of the bone-derived latent TGF beta complex by isolated osteoclasts Biochem Biophys Res Commun 1989. 158:817-23
» Mundy, GR, Yates, AJ Recent advances in pathophysiology and treatment of hypercalcemia of malignancy Am J Kidney Dis 1989. 14:2-12
» Mundy GR Hypercalcemia of Malignancy Metabolic Bone Disease: Cellular and Tissue Mechanisms. CS Tam, JNM Heersche, TM Murray (eds.), CRC Press, Florida 1989. :145-156
» Mundy GR Miscellaneous disorders of calcium and bone metabolism J Henry Ford Hospital 1989. 36:166-167
» Mundy, GR Malignant hypercalcemia Recent Advances in Endocrinology and Metabolism. CRW Edwards, Lincoln DW (eds). Churchill Livingstone 1989. Chapter 8:195-213
» Mundy, GR Anatomy, Physiology and function of Bone. Current Concepts Series, Upjohn Company 1989. :1-52
» Mundy, GR Local factors in bone remodeling Recent Prog Horm Res 1989. 45:507-27; discussion 527-31
» Bonewald, LF, Mundy, GR Role of transforming growth factor beta in bone remodeling: a review Connect Tissue Res 1989. 23:201-8
» Johnson, RA, Boyce, BF, Mundy, GR, Roodman, GD Tumors producing human tumor necrosis factor induced hypercalcemia and osteoclastic
bone resorption in nude mice Endocrinology 1989. 124:1424-7
» Mundy, GR Hypercalcemic factors other than parathyroid hormone-related protein Endocrinol Metab Clin North Am 1989. 18:795-806
» Boyce, BF, Aufdemorte, TB, Garrett, IR, Yates, AJ, Mundy, GR Effects of interleukin-1 on bone turnover in normal mice Endocrinology 1989. 125:1142-50
» Garrett, IR, Mundy, GR Relationship between interleukin-1 and prostaglandins in resorbing neonatal
calvaria J Bone Miner Res 1989. 4:789-94
» Boyce, BF, Yates, AJ, Mundy, GR Bolus injections of recombinant human interleukin-1 cause transient hypocalcemia
in normal mice Endocrinology 1989. 125:2780-3
» Mundy GR, Bonewald LF The effects of immune cell products on bone Macrophage-derived cell regulatory factors. Sorg C (ed), Cytokines Basel, Karger 1989. 1:38-53
» Takahashi, N, Yamana, H, Yoshiki, S, Roodman, GD, Mundy, GR, Jones, SJ, Boyde, A, Suda, T Osteoclast-like cell formation and its regulation by osteotropic hormones in
mouse bone marrow cultures Endocrinology 1988. 122:1373-82
» Pizurki L, Rizzoli R, Caverzasio J, Mundy G, Bonjour JP Factor derived from human lung carcinoma associated with hypercalcemia mimics the effects of parathyroid hormone on phosphate transport in cultured renal epithelia J Bone Miner Res 1988. 3:233-239
» Mundy, GR Hypercalcemia of malignancy revisited J Clin Invest 1988. 82:1-6
» Mundy GR, Bonewald LF, Roodman GD, Chenu C, Oreffo ROC, Pfeilschifter J TGFβ and bone remodeling Progress in Endocrinology, H Imura, K Shizume, S Yoshida (eds.), Excerpta Medica, New York 1988. 2:927-931
» Mundy GR, Bonewald LF, Roodman GD, Chenu C, Oreffo R, Pfeilschifter J TGFβ and bone remodeling Proceedings from the 8th International Congress of Endocrinology, Kyoto, Japan, Elsevier, Amsterdam 1988. :
» Mundy GR Cytokines and Osteoclasts Presented at the International Symposium on Calcium Regulating Systems - VIth Fuji Hormone Conference. Japan 1988. :
» Pfeilschifter, J, Seyedin, SM, Mundy, GR Transforming growth factor beta inhibits bone resorption in fetal rat long
bone cultures J Clin Invest 1988. 82:680-5
» Chenu, C, Pfeilschifter, J, Mundy, GR, Roodman, GD Transforming growth factor beta inhibits formation of osteoclast-like cells
in long-term human marrow cultures Proc Natl Acad Sci U S A 1988. 85:5683-7
» Yates, AJ, Gutierrez, GE, Smolens, P, Travis, PS, Katz, MS, Aufdemorte, TB, Boyce, BF, Hymer, TK, Poser, JW, Mundy, GR Effects of a synthetic peptide of a parathyroid hormone-related protein on
calcium homeostasis, renal tubular calcium reabsorption, and bone metabolism in vivo and in vitro in
rodents J Clin Invest 1988. 81:932-8
» Mundy GR Miscellaneous disorders of calcium and bone metabolism J Henry Ford Hospital 1988. 36:166-167
» Mundy, GR Treatment options for hypercalcemia of malignancy Hospital Therapy 1988. 13:52-65
» Sabatini, M, Boyce, B, Aufdemorte, T, Bonewald, L, Mundy, GR Infusions of recombinant human interleukins 1 alpha and 1 beta cause hypercalcemia
in normal mice Proc Natl Acad Sci U S A 1988. 85:5235-9
» MacDonald, BR, Takahashi, N, McManus, LM, Holahan, J, Mundy, GR, Roodman, GD Formation of multinucleated cells that respond to osteotropic hormones in long
term human bone marrow cultures Endocrinology 1987. 120:2326-33
» Mundy, GR Tumor products and the hypercalcemia of malignancy Rev Med Brux 1987. 8:353-7
» Mundy, GR Osteopenia Dis Mon 1987. 33:537-600
» Gutierrez, GE, Mundy, GR, Derynck, R, Hewlett, EL, Katz, MS Inhibition of parathyroid hormone-responsive adenylate cyclase in clonal osteoblast-like
cells by transforming growth factor alpha and epidermal growth factor J Biol Chem 1987. 262:15845-50
» Mundy, GR Ectopic hormonal syndromes in neoplastic disease Hosp Pract (Off Ed) 1987. 22:179-81, 185-7, 191-4
» Pfeilschifter, J, D''Souza, SM, Mundy, GR Effects of transforming growth factor-beta on osteoblastic osteosarcoma cells Endocrinology 1987. 121:212-8
» Takahashi, N, Mundy, GR, Kuehl, TJ, Roodman, GD Osteoclast-like cell formation in fetal and newborn long-term baboon marrow
cultures is more sensitive to 1,25-dihydroxyvitamin D3 than adult long-term marrow cultures J Bone Miner Res 1987. 2:311-7
» Garrett, IR, Durie, BG, Nedwin, GE, Gillespie, A, Bringman, T, Sabatini, M, Bertolini, DR, Mundy, GR Production of lymphotoxin, a bone-resorbing cytokine, by cultured human myeloma
cells N Engl J Med 1987. 317:526-32
» Mundy, GR Bone resorption and turnover in health and disease Bone 1987. 8 Suppl 1:S9-16
» Mundy, GR The hypercalcemia of malignancy Kidney Int 1987. 31:142-55
» Thomson, BM, Mundy, GR, Chambers, TJ Tumor necrosis factors alpha and beta induce osteoblastic cells to stimulate
osteoclastic bone resorption J Immunol 1987. 138:775-9
» Pfeilschifter, J, Mundy, GR Modulation of type beta transforming growth factor activity in bone cultures
by osteotropic hormones Proc Natl Acad Sci U S A 1987. 84:2024-8
» Martin, TJ, Mundy, GR Hypercalcemia and Calcium Regulating Hormones in Malignancy clinical Endocrinology of Calcium Metabolism 1987. :171-199
» Mundy, GR Fibrous dysplasia Internal Medicine, J.H. Stein, (ed.) 2nd edition 1987. :Chapter 316, 2117-2118
» Mundy, GR Osteoporosis Internal Medicine, J.H. Stein, (ed.) 2nd edition 1987. :Chapter 315, 2115-2116
» Mundy, GR Diagnostic Approach to Bone and Mineral Disorders Internal Medicine, J.H. Stein, (ed.) 2nd edition 1987. :Chapter 281, 1855-1860
» Mundy, GR Physiology of Bone Mineral Homeostasis Internal Medicine, J.H. Stein, (ed.) 2nd edition 1987. :Chapter 278, 1818-1824
» Pfeilschifter J, Mundy GR TGFβ stimulates osteoblast activity and is released during the bone resorption process Calcium Regulation and Bone Metabolism: Basic and clinical aspects. Cohn DV, Martin TJ, Meunier PJ (eds.), Elsevier Science Publishers 1987. 9:450-454
» Smith, DD, Gowen, M, Mundy, GR Effects of interferon-gamma and other cytokines on collagen synthesis in fetal
rat bone cultures Endocrinology 1987. 120:2494-9
» Mundy, GR Malignant Disease and the Skeleton Internal Medicine, J.H. Stein, (ed.), 2nd edition 1987. :Chapter 319, 2128-2134
» Mundy, GR, Roodman, GD Osteoclast ontogeny and function Bone and Mineral Research V, Elsevier, Peck WA (ed) 1987. Chapter 5:209-280
» Reasner C, Mundy GR Management of hypercalcemia J Intensive Care Medicine 1986. 1:319-328
» Ibbotson KJ, DSouza SM, Mundy GR Transforming growth factors and bone. Presented at the Development and Diseases of Cartilage and Bone Matrix. UCLA Symposium on Molecular and Cellular Biology 1986. 46, edited by A. Sen and T. Thornhill, Alan Liss, New York:
» Mundy GR Calcium homeostasis - The new horizons Ionized Calcium: Its Determination and Clinical Usefulness, Proceedings of an International Symposium, Galveston, Texas. Edited by RF Moran 1986. :1-5
» MacDonald, BR, Mundy, GR, Clark, S, Wang, EA, Kuehl, TJ, Stanley, ER, Roodman, GD Effects of human recombinant CSF-GM and highly purified CSF-1 on the formation
of multinucleated cells with osteoclast characteristics in long-term bone marrow cultures J Bone Miner Res 1986. 1:227-33
» Bertolini, DR, Nedwin, GE, Bringman, TS, Smith, DD, Mundy, GR Stimulation of bone resorption and inhibition of bone formation in vitro by
human tumour necrosis factors Nature 1986. 319:516-8
» Boyde, A, Maconnachie, E, Reid, SA, Delling, G, Mundy, GR Scanning electron microscopy in bone pathology: review of methods, potential
and applications Scan Electron Microsc 1986. :1537-54
» Gowen, M, Mundy, GR Actions of recombinant interleukin 1, interleukin 2, and interferon-gamma on
bone resorption in vitro J Immunol 1986. 136:2478-82
» Mundy, GR Calcitonin and 1,25D dihydroxyvitamin D in the treatment of osteoporosis J Musculoskeletal Med 1986. 3:13-20
» Takahashi, N, Mundy, GR, Roodman, GD Recombinant human interferon-gamma inhibits formation of human osteoclast-like
cells J Immunol 1986. 137:3544-9
» Takahashi, N, MacDonald, BR, Hon, J, Winkler, ME, Derynck, R, Mundy, GR, Roodman, GD Recombinant human transforming growth factor-alpha stimulates the formation
of osteoclast-like cells in long-term human marrow cultures J Clin Invest 1986. 78:894-8
» Gowen, M, Nedwin, GE, Mundy, GR Preferential inhibition of cytokine-stimulated bone resorption by recombinant
interferon gamma J Bone Miner Res 1986. 1:469-74
» Mundy, GR, Bertolini, DR Bone destruction and hypercalcemia in plasma cell myeloma Semin Oncol 1986. 13:291-9
» Fetchick, DA, Bertolini, DR, Sarin, PS, Weintraub, ST, Mundy, GR, Dunn, JF Production of 1,25-dihydroxyvitamin D3 by human T cell lymphotrophic virus-I-transformed
lymphocytes J Clin Invest 1986. 78:592-6
» Fetchick, DA, Mundy, GR Hypercalcemia of malignancy: diagnosis and therapy Compr Ther 1986. 12:27-32
» Gutierrez, GE, Mundy, GR, Katz, MS Alterations in hormone-sensitive adenylate cyclase of cloned rat osteosarcoma
cells during long-term culture J Bone Miner Res 1986. 1:319-26
» D''Souza, SM, MacIntyre, I, Girgis, SI, Mundy, GR Human synthetic calcitonin gene-related peptide inhibits bone resorption in
vitro Endocrinology 1986. 119:58-61
» Ibbotson, KJ, Harrod, J, Gowen, M, D''Souza, S, Smith, DD, Winkler, ME, Derynck, R, Mundy, GR Human recombinant transforming growth factor alpha stimulates bone resorption
and inhibits formation in vitro Proc Natl Acad Sci U S A 1986. 83:2228-32
» Bertolini, DR, Mundy, GR Metastases to bone in mammals Progressive stages of neoplastic growth 1985. :
» Gowne, M, Wood, DD, Mundy, GR, Russell, RGG Studies on the actions of interleukin-1 on bone metabolism: IL-1 stimulation of bone cell proliferation, and inhibition of IL-1-induced bone resorption by interferon gamma Brit J Rheum 1985. 24:147-149
» Ibbotson, KJ, Twardzik, DR, D''Souza, SM, Hargreaves, WR, Todaro, GJ, Mundy, GR Stimulation of bone resorption in vitro by synthetic transforming growth factor-alpha Science 1985. 228:1007-9
» Valentin-Opran, A, Eilon, G, Saez, S, Mundy, GR Estrogens and antiestrogens stimulate release of bone resorbing activity by
cultured human breast cancer cells J Clin Invest 1985. 75:726-31
» Roodman, GD, Ibbotson, KJ, MacDonald, BR, Kuehl, TJ, Mundy, GR 1,25-Dihydroxyvitamin D3 causes formation of multinucleated cells with several
osteoclast characteristics in cultures of primate marrow Proc Natl Acad Sci U S A 1985. 82:8213-7
» Mundy, GR Pathogenesis of hypercalcaemia of malignancy Clin Endocrinol (Oxf) 1985. 23:705-14
» Ibbotson, KJ, D''Souza, SM, Smith, DD, Carpenter, G, Mundy, GR EGF receptor antiserum inhibits bone resorbing activity produced by a rat Leydig
cell tumor associated with the humoral hypercalcemia of malignancy Endocrinology 1985. 116:469-71
» Mundy, GR Metabolic bone disease Trans Assoc Life Insur Med Dir Am 1985. 67:69-78
» Mundy, GR, Ibbotson, KJ, D''Souza, SM Tumor products and the hypercalcemia of malignancy J Clin Invest 1985. 76:391-4
» Simpson, E, Harrod, J, Eilon, G, Jacobs, JW, Mundy, GR Identification of a messenger ribonucleic acid fraction in human prostatic
cancer cells coding for a novel osteoblast-stimulating factor Endocrinology 1985. 117:1615-20
» Mundy, GR, Ibbotson KJ, D'Souza, SM, Bertolini, DR Animal models for tumor hypercalcemia Bone Resorption, Metastasis, and Disphosphonates 1984. :7-16
» Mundy, GR, Ibbotson, KJ, D'Souza, SM, Bertolini, DR Growth factors and bone resorption Endocrine Control of Bone and Calcium Metabolism. Cohn DV, Potts JT, Fujita T, (eds), Elsevier Science Publishers 1984. 8B:30-33
» Mundy, GR, Bertolini DR Osteoclast activating factor F Labrie, L Proulx (eds.) Endocrinology International Congress Series 665, Excerpta Medica 1984. :287-590
» Gutierrez, GE, Mundy, GR, Katz, MS Adenylate cyclase of osteoblast-like cells from rat osteosarcoma is stimulated
by calcitonin as well as parathyroid hormone Endocrinology 1984. 115:2342-6
» Mundy, GR, Ibbotson, KJ, D''Souza, SM, Simpson, EL, Jacobs, JW, Martin, TJ The hypercalcemia of cancer. Clinical implications and pathogenic mechanisms N Engl J Med 1984. 310:1718-27
» D''Souza, SM, Ibbotson, KJ, Mundy, GR Failure of parathyroid hormone antagonists to inhibit in vitro bone resorbing
activity produced by two animal models of the humoral hypercalcemia of malignancy J Clin Invest 1984. 74:1104-7
» Ibbotson, KJ, Roodman, GD, McManus, LM, Mundy, GR Identification and characterization of osteoclast-like cells and their progenitors
in cultures of feline marrow mononuclear cells J Cell Biol 1984. 99:471-80
» D''Souza, SM, Ibbotson, KJ, Smith, DD, Mundy, GR Production of a macromolecular bone-resorbing factor by the hypercalcemic variant
of the walker rat carcinosarcoma Endocrinology 1984. 115:1746-52
» Mundy, GR, Jacobs JW, Ibbotson, KJ, D'Souza, SM, Bertolini, DR, Simpson, EL Hypercalcemia of malignancy Endocrine control of bone and calcium metabolism 1984. :278-283
» Mundy, GR The management of osteoporosis Compr Ther 1983. 9:27-32
» Sica, DA, Martodam, RR, Aronow, J, Mundy, GR The hypercalcemic rat Leydig cell tumor--a model of the humoral hypercalcemia
of malignancy Calcif Tissue Int 1983. 35:287-93
» Rodan, SB, Insogna, KL, Vignery, AM, Stewart, AF, Broadus, AE, D''Souza, SM, Bertolini, DR, Mundy, GR, Rodan, GA Factors associated with humoral hypercalcemia of malignancy stimulate adenylate
cyclase in osteoblastic cells J Clin Invest 1983. 72:1511-5
» Eilon, G, Mundy, GR Association of increased cyclic adenosine 3'':5''-monophosphate content in cultured
human breast cancer cells and release of hydrolytic enzymes and bone-resorbing activity Cancer Res 1983. 43:5792-4
» Mantle, PG, Perera, KP, Maishman, NJ, Mundy, GR Biosynthesis of penitrems and roquefortine by Penicillium crustosum Appl Environ Microbiol 1983. 45:1486-90
» Adams, ND, Mundy, GR Therapy of hyper- and hypoparathyroidism Current Therapy, HF Conn, editor 1983. :480-484
» Mundy, GR, Wilkinson, R, Heath, DA Comparative study of available medical therapy for hypercalcemia of malignancy Am J Med 1983. 74:421-32
» Martodam, RR, Thornton, KS, Sica, DA, D''Souza, SM, Flora, L, Mundy, GR The effects of dichloromethylene diphosphonate on hypercalcemia and other parameters
of the humoral hypercalcemia of malignancy in the rat Leydig cell tumor Calcif Tissue Int 1983. 35:512-9
» Mundy, GR Monocyte-macrophage system and bone resorption Lab Invest 1983. 49:119-21
» Simpson, EL, Mundy, GR, D''Souza, SM, Ibbotson, KJ, Bockman, R, Jacobs, JW Absence of parathyroid hormone messenger RNA in nonparathyroid tumors associated
with hypercalcemia N Engl J Med 1983. 309:325-30
» Adams, ND, Mundy, GR Clinical disorders of vitamin D metabolism Contemporary Issues in Nephrology: Divalent Ion-Homestasis 1983. II:107-149
» Ibbotson, KJ, D''Souza, SM, Ng, KW, Osborne, CK, Niall, M, Martin, TJ, Mundy, GR Tumor-derived growth factor increases bone resorption in a tumor associated
with humoral hypercalcemia of malignancy Science 1983. 221:1292-4
» D'Souza, S, Mundy, GR Humoral regulation of fetal skeletal growth and development Perinatal Calcium and Phosphorus Metabolism 1983. :233-257
» Mundy, GR Physiology and pathophysiology of bone resorption Verhandlungen der Deutschen Gaesellschaft fur innere Medizin 89 1983. :1247-1249
» Adams, ND, Mundy, GR Clinical disorders of vitamin D metabolism Contemporary Issues of Nephrology 1983. II:107-149
» Mundy, GR, Poser, JW Chemotactic activity of the gamma-carboxyglutamic acid containing protein in
bone Calcif Tissue Int 1983. 35:164-8
» Mundy, GR Role of monocytes in bone resorption Adv Exp Med Biol 1982. 151:401-8
» Yoneda, T, Mundy, GR Release of the lymphokine osteoclast activating factor requires cyclic AMP
accumulation Calcif Tissue Int 1982. 34:204-8
» Mundy, GR, Martin, TJ The hypercalcemia of malignancy: pathogenesis and management Metabolism 1982. 31:1247-77
» Mundy, GR, Rodan, SB, Majeska, RJ, DeMartino, S, Trimmier, C, Martin, TJ, Rodan, GA Unidirectional migration of osteosarcoma cells with osteoblast characteristics
in response to products of bone resorption Calcif Tissue Int 1982. 34:542-6
» Mundy, GR Involvement of prostaglandin synthesis in mechanisms of malignant hypercalcemia Prostaglandins and Cancer 1982. :501-511
» Eilon, G, Mundy, GR Effects of inhibition of microtubule assembly on bone mineral release and enzyme
release by human breast cancer cells J Clin Invest 1981. 67:69-76
» Durie, BG, Salmon, SE, Mundy, GR Relation of osteoclast activating factor production to extent of bone disease
in multiple myeloma Br J Haematol 1981. 47:21-30
» Josse, RG, Murray, TM, Mundy, GR, Jez, D, Heersche, JN Observations on the mechanism of bone resorption induced by multiple myeloma
marrow culture fluids and partially purified osteoclast-activating factor J Clin Invest 1981. 67:1472-81
» Mundy, GR, Raisz, LG Recent advances in the therapy of disorders of calcium and bone metabolism Yearbook of Drug Therapy 1981. :7-30
» Mundy, GR, DeMartino, S, Rowe, DW Collagen and collagen-derived fragments are chemotactic for tumor cells J Clin Invest 1981. 68:1102-5
» Mundy, GR Control of osteoclast function by lumphokines in health and disease Lymphokines 1981. :395-408
» Mundy, GR, Yoneda T Monocytes: Interactions with bone cells and lymphocytes during bone resorption Hormonal Control of Calcium Metabolism 1981. :178-181
» Mundy, GR Local factors controlling bone resorption Calcif Tissue Int 1981. 33:
» Mundy, GR Clinical recognition and management of hypercalcemia in neoplastic disease Intern Med 1981. 2:37-46
» Reeves, J, Arnaud S, Gordon, S, Subryan, B, Block, M, Huffer, W, Arnaud, C, Mundy, G, Haussler, M The pathogenesis of infantile malignant osteopetrosis: Bone mineral metabolism and complications in five infants Metab Bone Dis Rel Res 1981. 3:135-142
» Mundy, GR, Raisz, LG Disorders of bone resorption Disorders of Mineral Metabolism 1981. III:1-66
» Heath, H, Weller, RE, Mundy, GR Canine lymphosarcoma: a model for study of the hypercalcemia of cancer Calcif Tissue Int 1980. 30:127-33
» Mundy, GR, Cove, DH, Fisken, R Primary hyperparathyroidism: changes in the pattern of clinical presentation Lancet 1980. 1:1317-20
» Binstock, ML, Mundy, GR Effect of calcitonin and glutocorticoids in combination on the hypercalcemia
of malignancy Ann Intern Med 1980. 93:269-72
» Mundy, GR, Yoneda T Osteoclast activating factor (OAF) production is dependent on prostaglandin synthesis by monocytes Biochemical Characterization of Lymphokines 1980. :123-127
» Mundy, GR, Eilon G, Spiro TP, Yoneda T Osteoclast activating factor and other mechanisms of hypercalcemia in malignancy Metab Bone Dis Rel Res 1980. 2:173-176
» Spiro, TP, Mundy, GR In vitro migraton of Walker 256 carcinosarcoma cells: dependence on microtubule
and microfilament function J Natl Cancer Inst 1980. 65:463-7
» McMillan, P, Mundy, G, Mayer, P Hypercalcaemia and osteolytic bone lesions in chronic lymphocytic leukaemia Brit Med J 1980. 281:1107
» Mundy, GR Bone resorbing factors in myeloma Workshops on Recent Advances and Future Trends in Myeloma 1980. :70-76
» Dominguez, JH, Mundy, GR Monocytes mediate osteoclastic bone resorption by prostaglandin production Calcif Tissue Int 1980. 31:29-34
» Orr, FW, Varani, J, Gondek, MD, Ward, PA, Mundy, GR Partial characterization of a bone-derived chemotactic factor for tumor cells Am J Pathol 1980. 99:43-52
» Mundy, GR, Spiro TP The mechanisms of bone metastasis and bone destruction by tumor cells Bone Metastasis 1980. 4:64-82
» Mundy, GR, Raisz, LG Thryotoxicosis and calcium metabolism Min Electrol Metab 1979. 2:285-292
» Yoneda, T, Mundy, GR Monocytes regulate osteoclast-activating factor production by releasing prostaglandins J Exp Med 1979. 150:338-50
» Dietrich, JW, Mundy, GR, Raisz, LG Inhibition of bone resorption in tissue culture by membrane-stabilizing drugs Endocrinology 1979. 104:1644-8
» Orr, W, Varani, J, Gondex, MK, Ward, PA, Mundy, GR Chemotactic responses of tumor cells to products of resorbing bone Science 1979. 203:176-9
» Yoneda, T, Mundy, GR Prostaglandins are necessary for osteoclast-activating factor production by
activated peripheral blood leukocytes J Exp Med 1979. 149:279-83
» Zurier, RB, Mundy, GR Pagets disease of bone The Science and Practice of Clinical Medicine, Vol. 4, Rheumatology and Immunology 1979. 4:352-354
» Mundy, GR, Varani, J, Orr, W, Gondek, MD, Ward, PA Resorbing bone is chemotactic for monocytes Nature 1978. 275:132-5
» Mundy, GR Differential diagnosis of osteopenia Hosp Pract 1978. 13:65-72
» Eilon, G, Mundy, GR Direct resorption of bone by human breast cancer cells in vitro Nature 1978. 276:726-8
» Altman, AJ, Bandelin JG, Dominguez, JH, Mundy GR Differentiation of isolated calvarial cells into a mature heterogeneous bone cell population in culture Metab Bone Dis Rel Res 1978. 1:75-79
» Mundy, GR, Rick, ME, Turcotte, R, Kowalski, MA Pathogenesis of hypercalcemia in lymphosarcoma cell leukemia. Role of an osteoclast
activating factor-like substance and a mechanism of action for glucocorticoid therapy Am J Med 1978. 65:600-6
» Strumpf, M, Kowalski, MA, Mundy, GR Effects of glucocorticoids on osteoclast-activating factor J Lab Clin Med 1978. 92:772-8
» Mundy, GR Calcium and cancer Life Sci 1978. 23:1735-44
» Koeffler, HP, Mundy, GR, Golde, DW, Cline, MJ Production of bone resorbing activity in poorly differentiated monocytic malignancy Cancer 1978. 41:2438-43
» Durie, BG, Mundy, GR, Salmon, SE Multiple Myeloma: clinical staging and role of oseoclast activating factor in localized bone loss Mechanisms of localilzed bone loss 1978. :319-330
» Raisz, LG, Mundy, GR, Eilon, G Hypercalcemia of neoplastic diseases Endocrinology of Calcium Metabolism, Copp DH, Talmage RV (eds), Excerpta Medica, Amsterdam 1978. :64-70
» Mundy, GR, Eilon G, Altman AJ, Dominguez, JH Non-bone cell mediated bone resorption. Mechanisms of localized bone loss 1978. :229-238
» Canalis, EM, Mundy, GR, Raisz, LG Hypercalcemia: diagnosis and therapy Conn Med 1977. 41:16-21
» Mundy, GR Medical grand rounds: from the dempsey hospital of the University of Connecticut.
The pathogenesis and therapy of a case of malignant hypercalcemia. Case presentation Conn Med 1977. 41:151-5
» Mundy, GR, Canalis, EM, Raisz, LG Calcium and the kidney: renal osteodystrophy and renal calculi Conn Med 1977. 41:205-9
» Mundy, GR, Raisz, LG, Shapiro, JL, Bandelin, JG, Turcotte, RJ Big and little forms of osteoclast activating factor J Clin Invest 1977. 60:122-8
» Sherline, P, Mundy, GR Role of the tubulin-microtubule system in lymphocyte activation J Cell Biol 1977. 74:371-6
» Raisz, LG, Mundy, GR, Dietrich, JW, Canalis, EM Hormonal regulation of mineral metabolism Int Rev Physiol 1977. 16:199-240
» Canalis, EM, Mundy, GR, Raisz, LG Paget''s disease of bone: recent advances in therapy Conn Med 1977. 41:79-83
» Mundy, GR, Raisz, LG Osteoclast activating factor Cholesteatoma-First International Conference. 1977. :149-151
» Mundy, GR, Altman AJ, Gondek, M, Bandelin, JG Direct resorption of bone by human monocytes. Science 1977. 196:1109-1111
» Gailani, S, McLimans, WF, Mundy, GR, Nussbaum, A, Roholt, O, Zeigel, R Controlled environment culture of bone marrow explants from human myeloma Cancer Res 1976. 36:1299-304
» Mundy, GR, Raisz, LG, Cooper, RA, Schechter, GP, Salmon, SE Evidence for the secretion of an osteoclast stimulating factor in myeloma Yearbook of Cancer 1976. :209-211
» Fleckenstein, L, Mundy, GR, Horovitz, RA, Mazzullo, JM Sodium salicylamide: relative bioavailability and subjective effects Clin Pharmacol Ther 1976. 19:451-8
» Mundy, GR, Canalis, EM, Raisz, LG Osteopenia: osteoporosis, osteomalacia and other forms of decreased mineralized
bone mass Conn Med 1976. 40:753-7
» Mundy, GR, Canalis, EM, Raisz, LG Modern concepts of calcium homeostasis Conn Med 1976. 40:680-4
» Mundy, GR, Shapiro, JL, Bandelin, JG, Canalis, EM, Raisz, LG Direct stimulation of bone resorption by thyroid hormones J Clin Invest 1976. 58:529-34
» Mundy, GR, Raisz, LG Applied pharmacology of anti-hypertensive drugs Conn Med 1976. 40:169-74
» Raisz, LG, Luben, RA, Mundy, GR, Dietrich, JW, Horton, JE, Trummel, CL Effect of osteoclast activating factor from human leukocytes on bone metabolism J Clin Invest 1975. 56:408-13
» Trummel, CL, Mundy, GR, Raisz, LG Release of osteoclast activating factor by normal human peripheral blood leukocytes J Lab Clin Med 1975. 85:1001-7
» Mundy, GR, Raisz, LG Calcitonin: Background and uses Drug Therapy 1975. :38-42
» Raisz, LG, Mundy, GR, Luben, RA Skeletal reactions to neoplasms Ann N Y Acad Sci 1974. 230:473-5
» Mundy, GR, Fleckenstein, L, Mazzullo, JM, Sundaresan, PR, Weintraub, M, Lasagna, L Current medical practice and the Food and Drug Administration. Some evidence
for the existing gap JAMA 1974. 229:1744-8
» Mundy, GR, Raisz, LG, Cooper, RA, Schechter, GP, Salmon, SE Evidence for the secretion of an osteoclast stimulating factor in myeloma N Engl J Med 1974. 291:1041-6
» Luben, RA, Mundy, GR, Trummel, CL, Raisz, LG Partial purification of osteoclast-activating factor from phytohemagglutinin-stimulated
human leukocytes J Clin Invest 1974. 53:1473-80
» Raisz, LG, Trummel, CL, Mundy, GR, Luben, RA Immunologic factors influencing bone resorption: Role of osteoclast activating factor from human lymphocyes and complement-mediated prostaglandin synthesis. Proceedings of the 5th International Parathyroid Conference, Oxford, England (Excerpta Medica) 1974. :149-153
» Mundy, GR, Raisz, LG Drugs for disorders of bone: pharmacological and clinical considerations Drugs 1974. 8:250-89
» Mundy, GR, Luben, RA, Raisz, LG, Oppenheim, JJ, Buell, DN Bone-resorbing activity in supernatants from lymphoid cell lines N Engl J Med 1974. 290:867-71
» Mundy, GR, Raisz, LG Drugs for disorders of bones New Ethic Med Prog 1974. 11:165-199
» Mundy, GR, Baikie, AG Myeloma treated with cyclophosphamide and terminating in reticulum cell sarcoma Med J Aust 1973. 1:1240-1
» Mundy, GR DNA values in myeloma Cancer 1973. 32:61-8
» Mundy, GR, McPherson, DG Variations in serum cholesterol levels after myocardial infarction Med J Aust 1973. 1:278-82
» Dartnall, JA, Mundy, GR, Baikie, AG Cytogenetic studies in myeloma Blood 1973. 42:229-39
» Mundy, GR Cytogenic Studies and DNA Content in Myeloma, with Reference to Other Features of the Disease M.D. Thesis, University of Tasmania 1972. :
» Mundy, GR, Cutforth, RH The relationship between serum lipid abnormalities and other major risk factors
in myocardial infarction Aust N Z J Med 1972. 2:8-12
» Mundy, GR, Cutforth, R, Brooks, PM Serum lipid abnormalities and the atrial pacing test Med J Aust 1972. 2:535-7
» Mundy, GR Infectious mononucleosis with pulmonary parenchymal involvement Br Med J 1972. 1:219-20
» Mundy, GR, MacDonald, CB Atypical presentations of diffuse fibrosing alveolitis Br J Dis Chest 1972. 66:261-7
» Baikie, AG, Macdonald, CB, Mundy, GR Systemic nocardiosis treated with trimethoprim and sulphamethoxazole Lancet 1970. 2:261
» Freeman, JW, Mundy, GR, Beattie, RR, Ryan, C Cardiac abnormalities in poisoning with tricyclic antidepressants Br Med J 1969. 2:610-1
» Cutforth, R, Mitchell, RM, Mundy, GR Cytomegalovirus mononucleosis following renal haemodialysis Med J Aust 1968. 2:1103-4
» Mundy GR Pathophysiology of Osteoporosis Rheumatology 4th edition (in press). :
» Mundy GR Pathophysiiology of Osteoporosis In: Rheumatology 4th edition (in press). :
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