» Nakayama, A, Hill, KE, Austin, LM, Motley, AK, Burk, RF All regions of mouse brain are dependent on selenoprotein P for maintenance of selenium J Nutr 2007. 137:690-3

» Burk, RF, Christensen, JM, Maguire, MJ, Austin, LM, Whetsell, WO, May, JM, Hill, KE, Ebner, FF A combined deficiency of vitamins E and C causes severe central nervous system damage in guinea pigs J Nutr 2006. 136:1576-81

» Burk, RF, Hill, KE, Motley, AK, Austin, LM, Norsworthy, BK Deletion of selenoprotein P upregulates urinary selenium excretion and depresses whole-body selenium content Biochim Biophys Acta 2006. 1760:1789-93

» Peters, MM, Hill, KE, Burk, RF, Weeber, EJ Altered hippocampus synaptic function in selenoprotein P deficient mice Mol Neurodegener 2006. 1:12

» Burk, RF, Norsworthy, BK, Hill, KE, Motley, AK, Byrne, DW Effects of chemical form of selenium on plasma biomarkers in a high-dose human supplementation trial Cancer Epidemiol Biomarkers Prev 2006. 15:804-10

» Burk, RF, Hill, KE Selenoprotein P: an extracellular protein with unique physical characteristics and a role in selenium homeostasis Annu Rev Nutr 2005. 25:215-35

» Olson, GE, Winfrey, VP, Nagdas, SK, Hill, KE, Burk, RF Selenoprotein P is required for mouse sperm development Biol Reprod 2005. 73:201-11

» Ma, S, Hill, KE, Burk, RF, Caprioli, RM Mass spectrometric determination of selenenylsulfide linkages in rat selenoprotein P J Mass Spectrom 2005. 40:400-4

» Valentine, WM, Hill, KE, Austin, LM, Valentine, HL, Goldowitz, D, Burk, RF Brainstem axonal degeneration in mice with deletion of selenoprotein p Toxicol Pathol 2005. 33:570-6

» Burk, RF, Hill, KE Selenoprotein P: An Extracellular Protein with Unique Physical Characteristics and a Role in Selenium Homeostasis Annu Rev Nutr 2004. :

» Olson, GE, Winfrey, VP, Hill, KE, Burk, RF Sequential development of flagellar defects in spermatids and epididymal spermatozoa of selenium-deficient rats Reproduction 2004. 127:335-42

» Hill, KE, Zhou, J, McMahan, WJ, Motley, AK, Burk, RF Neurological dysfunction occurs in mice with targeted deletion of the selenoprotein P gene J Nutr 2004. 134:157-61

» Hill, Kristina E, Zhou, Jiadong, McMahan, Wendy J, Motley, Amy K, Atkins, John F, Gesteland, Raymond F, Burk, Raymond F Deletion of selenoprotein P alters distribution of selenium in the mouse J Biol Chem 2003. 278:13640-6

» Mostert, Volker, Hill, Kristina E, Burk, Raymond F Loss of activity of the selenoenzyme thioredoxin reductase causes induction of hepatic heme oxygenase-1 FEBS Lett 2003. 541:85-8

» Burk, Raymond F, Hill, Kristina E, Motley, Amy K Selenoprotein metabolism and function: evidence for more than one function for selenoprotein P J Nutr 2003. 133:1517S-20S

» Mostert, Volker, Hill, Kristina E, Ferris, Christopher D, Burk, Raymond F Selective induction of liver parenchymal cell heme oxygenase-1 in selenium-deficient rats Biol Chem 2003. 384:681-7

» Ma, Shuguang, Caprioli, Richard M, Hill, Kristina E, Burk, Raymond F Loss of selenium from selenoproteins: conversion of selenocysteine to dehydroalanine in vitro J Am Soc Mass Spectrom 2003. 14:593-600

» Ma, S, Hill, KE, Burk, RF, Caprioli, RM Mass spectrometric identification of N- and O-glycosylation sites of full-length rat selenoprotein P and determination of selenide-sulfide and disulfide linkages in the shortest isoform Biochemistry 2003. 42:9703-11

» Hill, KE, Montine, TJ, Motley, AK, Li, X, May, JM, Burk, RF Combined deficiency of vitamins E and C causes paralysis and death in guinea pigs Am J Clin Nutr 2003. 77:1484-8

» May, James M, Morrow, Jason D, Burk, Raymond F Thioredoxin reductase reduces lipid hydroperoxides and spares alpha-tocopherol Biochem Biophys Res Commun 2002. 292:45-9

» Burk, Raymond F Selenium, an antioxidant nutrient Nutr Clin Care 2002. 5:75-9

» Ma, Shuguang, Hill, Kristina E, Caprioli, Richard M, Burk, Raymond F Mass spectrometric characterization of full-length rat selenoprotein P and three isoforms shortened at the C terminus. Evidence that three UGA codons in the mRNA open reading frame have alternative functions of specifying selenocysteine insertion or translation termination J Biol Chem 2002. 277:12749-54

» Atkinson, J B, Hill, K E, Burk, R F Centrilobular endothelial cell injury by diquat in the selenium-deficient rat liver Lab Invest 2001. 81:193-200

» Hondal, R J, Ma, S, Caprioli, R M, Hill, K E, Burk, R F Heparin-binding histidine and lysine residues of rat selenoprotein P J Biol Chem 2001. 276:15823-31

» Li, X, Cobb, C E, Hill, K E, Burk, R F, May, J M Mitochondrial uptake and recycling of ascorbic acid Arch Biochem Biophys 2001. 387:143-53

» Hill, K E, Motley, A K, Li, X, May, J M, Burk, R F Combined selenium and vitamin E deficiency causes fatal myopathy in guinea pigs J Nutr 2001. 131:1798-802

» Burk, Raymond Selenium: recent clinical advances Curr Opin Gastroenterol 2001. 17:162-166

» Atkinson, J B, Hill, K E, Burk, R F Centrilobular endothelial cell injury by diquat in the selenium-deficient rat liver Lab Invest 2001. 81:193-200

» Burk, R F, Hill, K E, Motley, A K Plasma selenium in specific and non-specific forms Biofactors 2001. 14:107-14

» Li, X, Hill, K E, Burk, R F, May, J M Selenium spares ascorbate and alpha-tocopherol in cultured liver cell lines under oxidant stress FEBS Lett 2001. 508:489-92

» Yang, X., K.E. Hill, M.J. Maguire, and R.F. Burk Synthesis and secretion of selenoprotein P by cultured rat astrocytes Biochim Biophys Acta 2000. 1474:390-396

» Yang, X, Hill, K E, Maguire, M J, Burk, R F Synthesis and secretion of selenoprotein P by cultured rat astrocytes Biochim Biophys Acta 2000. 1474:390-6

» Burk, R F, Hill, K E Orphan selenoproteins Bioessays 1999. 21:231-7

» Hondal, R.J., A.K. Motley, K.E. Hill, and R.F. Burk Failure of selenomethionine residues in albumin to protect against peroxynitrite oxidation of dihydrorhodamine 123 Arch Biochem Biophys 1999. 37:29-34

» Hondal, R J, Motley, A K, Hill, K E, Burk, R F Failure of selenomethionine residues in albumin and immunoglobulin G to protect against peroxynitrite Arch Biochem Biophys 1999. 371:29-34

» Burk, R F, Early, D S, Hill, K E, Palmer, I S, Boeglin, M E Plasma selenium in patients with cirrhosis Hepatology 1998. 27:794-8

» May, J.M., C.E. Cobb, S. Mendiratta, K.E. Hill, and R.F. Burk Reduction of the ascorbyl free radical to ascorbate by thioredoxin reductase J Biol Chem 1998. 273:23039-23045

» May, J M, Cobb, C E, Mendiratta, S, Hill, K E, Burk, R F Reduction of the ascorbyl free radical to ascorbate by thioredoxin reductase J Biol Chem 1998. 273:23039-45

» Morrow, J D, Roberts, L J, Daniel, V C, Awad, J A, Mirochnitchenko, O, Swift, L L, Burk, R F Comparison of formation of D2/E2-isoprostanes and F2-isoprostanes in vitro and in vivo--effects of oxygen tension and glutathione Arch Biochem Biophys 1998. 353:160-71

» Hill, K E, McCollum, G W, Burk, R F Determination of thioredoxin reductase activity in rat liver supernatant Anal Biochem 1997. 253:123-5

» Hill, K E, Burk, R F Selenoprotein P: recent studies in rats and in humans Biomed Environ Sci 1997. 10:198-208

» May, J M, Mendiratta, S, Hill, K E, Burk, R F Reduction of dehydroascorbate to ascorbate by the selenoenzyme thioredoxin reductase J Biol Chem 1997. 272:22607-10

» Burk, R F, Hill, K E, Boeglin, M E, Ebner, F F, Chittum, H S Selenoprotein P associates with endothelial cells in rat tissues Histochem Cell Biol 1997. 108:11-5

» Hill, K E, McCollum, G W, Boeglin, M E, Burk, R F Thioredoxin reductase activity is decreased by selenium deficiency Biochem Biophys Res Commun 1997. 234:293-5

» Chittum, H S, Himeno, S, Hill, K E, Burk, R F Multiple forms of selenoprotein P in rat plasma Arch Biochem Biophys 1996. 325:124-8

» Hill, K E, Xia, Y, Akesson, B, Boeglin, M E, Burk, R F Selenoprotein P concentration in plasma is an index of selenium status in selenium-deficient and selenium-supplemented Chinese subjects J Nutr 1996. 126:138-45

» Payne, J L, McCarty, K R, Drougas, J G, Chapman, W C, Wright, J K, Pinson, N Y, Beliles, K E, Newsom, V L, Hunter, E B, Raiford, D S, Awad, J A, Burk, R F, Donovan, K L, Van Buren, D H, Pinson, C W Outcomes analysis for 50 liver transplant recipients: the Vanderbilt experience Am Surg 1996. 62:320-5

» Himeno, S, Chittum, H S, Burk, R F Isoforms of selenoprotein P in rat plasma. Evidence for a full-length form and another form that terminates at the second UGA in the open reading frame J Biol Chem 1996. 271:15769-75

» Hill, K E, Chittum, H S, Lyons, P R, Boeglin, M E, Burk, R F Effect of selenium on selenoprotein P expression in cultured liver cells Biochim Biophys Acta 1996. 1313:29-34

» Hill, K E, Dasouki, M, Phillips, J A, Burk, R F Human selenoprotein P gene maps to 5q31 Genomics 1996. 36:550-1

» Awad, J A, Roberts, L J, Burk, R F, Morrow, J D Isoprostanes--prostaglandin-like compounds formed in vivo independently of cyclooxygenase: use as clinical indicators of oxidant damage Gastroenterol Clin North Am 1996. 25:409-27

» Burk, R F, Hill, K E, Awad, J A, Morrow, J D, Lyons, P R Liver and kidney necrosis in selenium-deficient rats depleted of glutathione Lab Invest 1995. 72:723-30

» Burk, R F, Hill, K E, Awad, J A, Morrow, J D, Kato, T, Cockell, K A, Lyons, P R Pathogenesis of diquat-induced liver necrosis in selenium-deficient rats: assessment of the roles of lipid peroxidation and selenoprotein P Hepatology 1995. 21:561-9

» Burk, R F, Hill, K E Reduced glutathione release into rat plasma by extrahepatic tissues Am J Physiol 1995. 269:G396-9

» Burk, R F, Hill, K E Selenoprotein P. A selenium-rich extracellular glycoprotein J Nutr 1994. 124:1891-7

» Awad, J A, Morrow, J D, Hill, K E, Roberts, L J, Burk, R F Detection and localization of lipid peroxidation in selenium- and vitamin E-deficient rats using F2-isoprostanes J Nutr 1994. 124:810-6

» Awad, J A, Burk, R F, Roberts, L J Effect of selenium deficiency and glutathione-modulating agents on diquat toxicity and lipid peroxidation in rats J Pharmacol Exp Ther 1994. 270:858-64

» Akesson, B, Bellew, T, Burk, R F Purification of selenoprotein P from human plasma Biochim Biophys Acta 1994. 1204:243-9

» Drougas, J G, Hunter, E B, Raiford, D S, Burk, R F, Awad, J A, Wright, J K, Lopez, R R, Donovan, K L, Franks, J J, Thomas, A T Liver transplantation: results with Vanderbilt's first 25 liver recipients J Tenn Med Assoc 1994. 87:7-10

» Longmire, A W, Swift, L L, Roberts, L J, Awad, J A, Burk, R F, Morrow, J D Effect of oxygen tension on the generation of F2-isoprostanes and malondialdehyde in peroxidizing rat liver microsomes Biochem Pharmacol 1994. 47:1173-7

» Burk, R F Clinical effects of selenium deficiency Prog Clin Biol Res 1993. 380:181-90

» Burk, R F, Hill, K E Regulation of selenoproteins Annu Rev Nutr 1993. 13:65-81

» Hill, K E, Lloyd, R S, Burk, R F Conserved features of selenoprotein P cDNA Biochem Soc Trans 1993. 21:832-5

» Hill, K E, Lloyd, R S, Burk, R F Conserved nucleotide sequences in the open reading frame and 3' untranslated region of selenoprotein P mRNA Proc Natl Acad Sci U S A 1993. 90:537-41

» Hill, K E, Lyons, P R, Burk, R F Differential regulation of rat liver selenoprotein mRNAs in selenium deficiency Biochem Biophys Res Commun 1992. 185:260-3

» Hill, K E, Hunt, R W, Jones, R, Hoover, R L, Burk, R F Metabolism of nitroglycerin by smooth muscle cells. Involvement of glutathione and glutathione S-transferase Biochem Pharmacol 1992. 43:561-6

» Kato, T, Read, R, Rozga, J, Burk, R F Evidence for intestinal release of absorbed selenium in a form with high hepatic extraction Am J Physiol 1992. 262:G854-8

» Morrow, J D, Awad, J A, Kato, T, Takahashi, K, Badr, K F, Roberts, L J, Burk, R F Formation of novel non-cyclooxygenase-derived prostanoids (F2-isoprostanes) in carbon tetrachloride hepatotoxicity. An animal model of lipid peroxidation J Clin Invest 1992. 90:2502-7

» Burk, R F, Hill, K E Some properties of selenoprotein P Biol Trace Elem Res 1992. 33:151-3

» Morrow, J D, Hill, K E, Burk, R F, Nammour, T M, Badr, K F, Roberts, L J Formation of unique biologically active prostaglandins in vivo by a non-cyclooxygenase free radical catalyzed mechanism Adv Prostaglandin Thromboxane Leukot Res 1991. 21A:125-8

» Burk, R F Molecular biology of selenium with implications for its metabolism FASEB J 1991. 5:2274-9

» Burk, R F, Hill, K E, Read, R, Bellew, T Response of rat selenoprotein P to selenium administration and fate of its selenium Am J Physiol 1991. 261:E26-30

» Hill, K E, Lloyd, R S, Yang, J G, Read, R, Burk, R F The cDNA for rat selenoprotein P contains 10 TGA codons in the open reading frame J Biol Chem 1991. 266:10050-3

» Burk, R F Protection against free radical injury by selenoenzymes Pharmacol Ther 1990. 45:383-5

» Morrow, J D, Hill, K E, Burk, R F, Nammour, T M, Badr, K F, Roberts, L J A series of prostaglandin F2-like compounds are produced in vivo in humans by a non-cyclooxygenase, free radical-catalyzed mechanism Proc Natl Acad Sci U S A 1990. 87:9383-7

» Burk, R F, Hill, K E, Hunt, R W, Martin, A E Isoniazid potentiation of acetaminophen hepatotoxicity in the rat and 4-methylpyrazole inhibition of it Res Commun Chem Pathol Pharmacol 1990. 69:115-8

» Read, R, Bellew, T, Yang, J G, Hill, K E, Palmer, I S, Burk, R F Selenium and amino acid composition of selenoprotein P, the major selenoprotein in rat serum J Biol Chem 1990. 265:17899-905

» Williams, A T, Burk, R F Carbon tetrachloride hepatotoxicity: an example of free radical-mediated injury Semin Liver Dis 1990. 10:279-84

» Piao, JH, Hill, KE, Hunt, RW, Burk, RF Effect of selenium deficiency on tissue taurine concentration and urinary taurine excretion in the rat J Nutr Biochem 1990. 1:427-32

» Burk, R F, Ludden, T M Exhaled alkanes as indices of in vivo lipid peroxidation Biochem Pharmacol 1989. 38:1029-32

» Yang, J G, Hill, K E, Burk, R F Dietary selenium intake controls rat plasma selenoprotein P concentration J Nutr 1989. 119:1010-2

» Konz, K H, Haap, M, Hill, K E, Burk, R F, Walsh, R A Diastolic dysfunction of perfused rat hearts induced by hydrogen peroxide. Protective effect of selenium J Mol Cell Cardiol 1989. 21:789-95

» Hill, K E, Ziegler, D M, Konz, K H, Haap, M, Hunt, R W, Burk, R F Nitroglycerin and isosorbide dinitrate stimulation of glutathione disulfide efflux from perfused rat liver Biochem Pharmacol 1989. 38:3807-10

» Burk, R F Recent developments in trace element metabolism and function: newer roles of selenium in nutrition J Nutr 1989. 119:1051-4

» Burk, R F Selenium deficiency in search of a disease Hepatology 1988. 8:421-3

» Burk, R F, Hill, K E, Lane, J M Inhibition of CCl4 metabolism by oxygen varies between isoenzymes of cytochrome P-450 Biochem Biophys Res Commun 1988. 152:1463-7