Programs in ALLIED HEALTH CARDIOVASCULAR PERFUSION TECHNOLOGY

Vanderbilt University Medical Center

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PHARM 501
PHARMACOLOGY

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Course Description
This class provides the entry-level student with a detailed overview of cardiovascular pharmacology, to act as a basis for the understanding of the interactions of pharmacologic agents with the patient, both on and off bypass.

Course work will include both class time and observation within the surgical suite, as well as on the patient wards as warranted. Laboratory participation is an important aspect of perfusion training, and intensive participation in laboratory projects will further expose the student to pharmacokinetic and pharmacodynamic parameters as they effect both animal/patient models, and how that interaction may affect the conduct of perfusion.

Instructor: TBA
Location and meeting time: tba
Credit Hours: 3

Required Texts

Cardiac Drug Therapy
M. Gabriel Khan

Course Objectives

Pharm 501 will provide the detailed foundation and skills that are necessary to understand the interplay between the science of extracorporeal technology and the pharmacologic considerations that play a role in the initiation, maintenance, and termination of extracorporeal circulatory support. Students will understand the basic principles of recognition and diagnosis involved in determining the nature and extent of various pharmacologic interventions that may occur during extracorporeal support.

Upon completion of the course, students will be able to:

  1. Understand and discuss pharmacokinetics and pharmacodynamics
  2. Understand and discuss anticoagulant therapy and the measurement thereof
  3. Understand and discuss fibrinolytic and thrombolytic therapy
  4. Understand and discuss the roles of all blood elements and components, including the clotting cascades and aberrations thereof
  5. Understand and discuss cardiac electrophysiology
  6. Understand and discuss cardiac glycosides
  7. Understand and discuss calcium channel blockers
  8. Understand and discuss anti-arrhythmic agents
  9. Understand and discuss anti-anginal agents
  10. Understand and discuss the states of shock and hypotension
  11. Understand and discuss physiologic electrolyte concentrations within various tissues
  12. Understand and discuss diuretic therapy
  13. Understand and discuss narcotic and sedative therapy
  14. Understand and discuss anti-hypertensive therapies
  15. Understand and discuss acid-base management and mechanism
  16. Understand and discuss steroid therapy
  17. Understand and discuss bronchodilator therapy
  18. Understand and discuss anesthetic agents
  19. Understand and discuss muscle paralyzing agents
  20. Understand and discuss diabetic therapies
  21. Understand and discuss cardiac preserving/energy supplying agents
  22. Understand and discuss new cardiopulmonary and renal agents
  23. Understand and discuss medications regimens related to transplantation of organs
  24. Understand and discuss various antimicrobial agents/antibiotics commonly used.

Note: the Consensus Curriculum as created by the PPDC and adopted by the AC-PE in its present form should be considered as further evidence of curriculum, and the latest edition of said Curriculum is herein adopted and incorporated by reference regarding the subject matter.

 

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Programs in Allied Health:
Cardiovascular Perfusion Technology
URL: http://www.mc.Vanderbilt.Edu/cvpt/course-pharm501.htm

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