FIGURE 2. Lack of compensatory growth during pancreas development.  Excerpted from 'Organ size is limited by the number of embryonic progenitor cells in the pancreas but not the liver'.
COURSE MODULES
GENERAL COURSE INFORMATION
COURSE CONTACTS
Mark De Caestecker 
Course Director
Lynda Anderson, Ph.D.
Teaching Assistant
Jon Lowery
Student Mentor
Emily Cross
Student Mentor
John Mackert
Student Mentor
 


 

Cancer and Embryonic Development meets every Monday, Wednesday, and Friday from 2:30 to 3:30 pm in 3131 MRBIII.   We will have three graduate trainees and one postdoctoral fellow serving as teaching assistants and with their help will provide students with highly interactive, student-teacher environment.  This year, the course will be divided into 4 modules. 

The first module, Structure, Movement and Specification, will be offered from Friday, January 9 through February 6, 2009.  Presentations and readings for each class follow.

To download the presentation from each class simply click on the title.  Clicking on a reading will either take you to the webpage for the full article or pdf download or allow you to download the publication directly (in cases where the information is not available on the web).

I. STRUCTURE, MOVEMENT AND SPECIFICATION
1/9/09 FRIDAY Mark deCaestecker Introduction
1/12/09 David Bader Germ layers and organogenesis 
Development of the chick embryo mesoblast; pronephros, lateral plate, and early vasculature.  1980 Journal of Embryology 55; 291-306
1/14/09 Barbara Fingelton Cancer progression
Reading
The Microenvironment Controls CDX2 Homeobox Gene Expression in Colorectal Cells.  2007 The American Journal of Pathology 170: 733-744
1/16/09 Students Journal Club
1/19/09 Maureen Gannon Cell growth and survival development
Organ size is limited by the number of embryonic progenitor cells in the pancreas but not the liver.  2007 Nature 445: 886-891
1/21/09 Christine Eischen   Cell growth and survival in cancer
Induction of Apoptosis in Fibroblasts by c-myc Protein.  1992 Cell 69: 119-128
1/23/09 Students Journal Club
1/26/09 Jason Jessen Cell movement during development
Signaling pathways controlling primordial germ cell migration in zebrafish.  2004 Journal of Cell Science 117: 4787-4785
1/28/09 Andries Zijlstra Cell movement in cancer
cAMP-induced Epac-Rap activation inhibits epithelial cell migration by modulating focal adhesion and leading edge dynamics.  2008 Cellular Signalling 20: 1104-1116
1/30/09 Students Journal Club
2/2/09 Stacey Huppert Cell fate specification in development
Notch signaling controls hepatoblast differentiation by altering the expression of liver-enriched transcription factors.  2004 Journal of Cell Science 117: 3165-3174
2/4/09 Michael Cooper Cancer stem cells
Prominin 1 marks intestinal stem cells that are susceptible to neoplastic transformation.  2008 Nature Online, December 17 [ePub ahead of print]
Crypt stem cells as the cells-of-origin of intestinal cancer.  2008 Nature Online, December 17 [ePub ahead of print]
2/6/09 Students Journal Club
(For more information about CBIO320/CANB320 please contact
the Course Director or Course Assistants)

 

 

 

 

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Copyright 2004, Educational Technology, Biomedical Research Education & Training
Last modified: Thursday, February 12, 2009 by Kim.Kane@vanderbilt.edu