Schematic representation of early splenopancreatic development.  Excerpted from "Spleen versus pancreas: strict control of organ interrelationship revealed by analyses of Bapx1-/- mice".
COURSE MODULES
GENERAL COURSE INFORMATION
COURSE CONTACTS
Mark De Caestecker 
Course Director
Lynda Anderson, Ph.D.
Teaching Assistant
Jon Lowery
Student Mentor
Emily Cross
Student Mentor
John Mackert
Student Mentor


 

Cancer and Embryonic Development meets every Monday, Wednesday, and Friday from 2:30 to 3:30 pm in 3131 MRBIII.   We will have three graduate trainees and one postdoctoral fellow serving as teaching assistants and with their help will provide students with highly interactive, student-teacher environment.  This year, the course will be divided into 4 modules. 

The third module, Cell Interactions, will be offered from Monday, February 23 through Friday, March 20, 2009.  Presentations and readings for each class follow.

To download the presentation from each class simply click on the title.  Clicking on a reading will either take you to the webpage for the full article or pdf download or allow you to download the publication directly (in cases where the information is not available on the web).

III. CELL INTERACTIONS
2/23/09 Anna Means Cellular interactions development
Spleen versus pancreas: strict control of organ interrelationship revealed by analyses of Bapx1-/- mice.  2007 Genes & Development 20: 2208-2213
2/25/09 Simon Hayward Cellular interactions in cancer (not endothelial cells)
Reading
No evidence of clonal somatic genetic alteations in cancer-associated fibroblasts from human breast and ovarian carcinomas.  2007 Nature Genetics 40: 650
2/27/09 Students Journal Club
BREAK  
3/9/09 Stacey Huppert Stem Cell Nicehes in development
Live-animal tracking of individual haematopoietic stem/progenitor cells in their niche.  2009 Nature 457: 92-96
3/11/09 Michael Cooper Stem Cell Niches in malignancy
Reading
Leukemic cells create bone marrow niches that disrupt the behavior of normal hematopoietic progenitor cells.  2008 Science 322: 1861-1865
3/13/09 Students Journal Club
3/16/09 David Bader Endothelial patterning and tissue interactions during development
Induction of Pancreatic Differentiation by Signals from Blood Vessels.  2001 Science 294: 564-567
3/18/09 Ambra Pozzi Tumor-endothelium interactions
Reading
An essential role for SRC-activated STAT-3 in 14,15-EET-induced VEGF expression and angiogenesis.  2008 Blood 111; 5581-
3/20/09 Students Journal Club
(For more information about CBIO320/CANB320 please contact
the Course Director or Course Assistants)

 

 

 

 

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Copyright 2004, Educational Technology, Biomedical Research Education & Training
Last modified: Monday, March 16, 2009 by Kim.Kane@vanderbilt.edu