| MDB CONTACTS |
| Christopher V.E. Wright, D.Phil. Overall Course Director Module 3 Director |
| Anna Means, Ph.D. Module 1 Director |
| Dan DeLaughter Graduate Student Teaching Assistant |
| Laurie Lee, M.D., Ph.D. Module 2 Co-Director |
| Andrea Page-McCaw, Ph.D. Module 2 Co-Director |
| Billy Carver Graduate Student Teaching Assistant |
| Matt Bechard, Ph.D. Postdoctoral Fellow Teaching Assistant |
| Kimberly Kane Course Support |
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| Image courtesy of eccb2006.org |
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| Image courtesy of ddw-online |
Molecular Developmental Biology has been designed to familiarize students with 'hot button' developmental biology topics. Offered every other year through the department of Cell and Developmental Biology, the course has a three module structure with each module offering didactic lectures, guest speakers, literature discussions, and hands-on laboratory opportunities. The 'hot button' topics for 2012 are:
| Click on the appropriate module name for class specifics by date | |
| TUESDAY, JANUARY 17 - WEDNESDAY, FEBRUARY 15 | |
| MODULE
1 - SIZE MATTERS: REGULATION OF TISSUE GROWTH BY THE HIPPO/WARTS PATHWAY |
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| Anna Means, Ph.D. (Module Director) | |
| Dan DeLaughter (Graduate Student Teaching Assistant) | |
| This module will examine: | |
| How does one cell know when to divide, when to arrest, and when to die to allow the correct size of the organ as a whole? | |
| The Hippo/Warts pathway is a recently discovered regulator of communication between the cell and its environment. Disruption of this pathway either allows tissue overgrowth and tumor development or loss of growth and agenesis of the tissue. | |
| The Hippo/Warts pathway conscripts regulators of apical-basal polarity and planar cell polarity to coordinate growth with architectural changes in the tissue as a whole. | |
| This is a still developing field of developmental biology - many questions and controversies remain and will be discussed in the class. | |
| THURSDAY, FEBRUARY 16 - MONDAY, MARCH 19 | |
| MODULE 2 - MEIOSIS AND GERMLINE DEVELOPMENT | |
| Laurie Lee, M.D., Ph.D. (Module Director) | |
| Andrea Page-McCaw, Ph.D. (Module Director) | |
| Billy Carver (Graduate Student Teaching Assistant) | |
| This module will examine: | |
| Germline stem cells | |
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The relationship between soma and germline
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Imprinting
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Sex determination
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Regulation of the meiotic cell cycle
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| TUESDAY, MARCH 20 - THURSDAY, APRIL19 | |
| MODULE 3 - IPS & DIVIDED DIFFERENTIATION AND EPIGENETICS | |
| Christopher Wright, D. Phil. (Module Director) | |
| Matt Bechard, Ph.D. (Postdoctoral Fellow Teaching Assistant) | |
| Module 3 details will be listed soon | |
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Last modified:Monday, April 2, 2012 by
Kim.Kane@vanderbilt.edu