- In Vivo Metabolic
Regulation and Obesity - Islet Development,
Biology, and
Immunology - Complications of
Diabetes - Oxidative stress
- Signal transduction
and Gene Regulation - Clinical Research
- Translational Research
Clinical Research
The 21 investigators in this group seek to advance our understanding of the disordered clinical physiology and pathophysiology occurring in diabetes and are engaged in collaborative studies on the Vanderbilt General Clinical Research Center. Areas of investigation include: in-vivo mechanisms responsible for the disordered endothelial function and increased thrombogenesis found in type 1 and type 2 diabetes, autonomic nervous system control of cardiovascular and metabolic regulation in healthy, obese and diabetic man, energy balance and the effects of surgical interventions to reduce obesity and type 2 diabetes, morbid obesity is associated with significant endothelial dysfunction, insulin resistance, and type 2 DM, in-vivo mechanisms responsible for tissue complications occurring in patients with type 2 DM.
