Blakely Lab

The Blakely Lab

Randy Blakely, Ph.D.


Randy Headshot

Allan D. Bass Professor of Pharmacology and Psychiatry

Director, Silvio O. Conte Center for Neuroscience Research

Director, Vanderbilt Postdoctoral Training Program in Neurogenomics

Email: randy.blakely@vanderbilt.edu


THE BLAKELY LAB


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Randy D. Blakely, Ph. D.
Allan D. Bass Professor of Pharmacology and Psychiatry
Director, Silvio O. Conte Center for
Neuroscience Research
Vanderbilt Postdoctoral Training Program
in Functional Neurogenomics


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My laboratory explores mechanisms of synaptic regulation, focusing on how clearance of neurotransmitters by presynaptic and glial transporters regulates neurotransmitter signaling capacity. We use molecular biology, transcriptomic and proteomic methods, model system genetics (C. elegans, recombinant inbred mice), molecular and cellular imaging approaches, electrophysiological paradigms, and transgenic mouse approaches to identify mechanisms by which neurotransmitter transporters insure normal synaptic function and how disease risk is impacted by transporter dysfunction. We also seek to understand how drugs, including antidepressants (e.g. SSRIs) and psychostimulants (e.g. cocaine, ADHD medications) carry out their actions. Finally, we seek to understand the web of molecular interactions that act in concert with, or regulate neurotransmitter transporters to insure proper synaptic signaling and plasticity.



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Congratulations to Kristin Bater, the 2014 College of Arts and Science Founder's Medal Awardee.

An honors neuroscience major at Vanderbilt, Kristen began working in the Blakely Lab her sophomore year. Learn more about her research here.





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