Blakely Lab

The Blakely Lab

The Blakely Lab: Recent Publications


2014 Publications

Ye R, Carneiro AM, Airey D, Sanders-Bush E, Williams RW, Lu L, Wang J, Zhang B, Blakely RD. Evaluation of heritable determinants of blood and brain serotonin homeostasis using recombinant inbred mice. Genes Brain Behav. 2014 Mar;13(3):247-60. doi: 10.1111/gbb.12092. Epub 2013 Oct 31 [PMID: 24102824; PMCID: PMC3979832]


Gowrishankar R, Hahn MK, Blakely RD. Good riddance to dopamine: Roles for the dopamine transporter in synaptic function and dopamine-associated brain disorders. Neurochem Int. 2013 Nov 11. pii: S0197-0186(13)00289-1. doi: 10.1016/j.neuint.2013.10.016. Epub ahead of print [PMID: 24231471; PubMed – as supplied by publisher].


Holmstrand EC, Lund D., Cherian AK, Wright J, Martin RF, Ennis EA, Stanwood GD, Sarter M, Blakely RD. Transgenic overexpression of the presynaptic choline transporter elevates acetylcholine levels and augments motor endurance. Neurochem Int. 2013 Nov 22. pii: S0197-0186(13)00299-4. doi: 10.1016/j.neuint.2013.11.008. Epub ahead of print [PMID: 24274995; PubMed – as supplied by publisher].


Mergy MA, Gowrishankar R, Davis GL, Jessen TN, Wright J, Stanwood GD, Hahn MK, Blakely RD. Genetic targeting of the amphetamine and methylphenidate-sensitive dopamine transporter: On the path to an animal model of attention-deficit hyperactivity disorder. Neurochem Int. 2013 Dec 8. pii: S0197-0186(13)00306-9. doi: 10.1016/j.neuint.2013.11.009. Epub ahead of print [PMID: 24332984; PubMed – as supplied by publisher].


Rudnick G, Krämer R, Blakely RD, Murphy DL, Verrey F. The SLC6 transporters: perspectives on structure, functions, regulation, and models for transporter dysfunction. Pflugers Arch. 2014 Jan;466(1):25-42, doi: 10.1007/s00424-013-1410-1. Epub 2013 Dec 13 [PMID: 24337881, PMCID: PMC3930102].


Ye R, Carneiro AM, Han Q, Airey D, Sanders-Bush E, Zhang B, Lu L, Williams R, Blakely RD. Quantitative trait loci mapping and gene network analysis implicate protocadherin-15 as a determinant of brain serotonin transporter expression. Genes Brain Behav. 2014 Mar;13(3):261-75. doi: 10.1111/gbb.12119. Epub 2014 Feb 6 [PMID: 24405699; PubMed – in process].

Vollbrecht PJ, Simmler LD, Blakely RD, Deutch AY. Dopamine denervation of the prefrontal cortex increases expression of the astrocytic glutamate transporter GLT-1. J Neurochem, 2014 Feb 24. doi: 10.1111/jnc.12697, Epub ahead of print [PMID 24611756; PubMed—as supplied by publisher].


Berry AS, Demeter E, Sabhapathy S, English BA, Blakely RD, Sarter M, Lustig C. Disposed to Distraction: Genetic Variation in the Cholinergic System Influences Distractibility But Not Time-on-Task Effects. J Cogn Neurosci. 2014 Mar 25. Epub ahead of print [PMID: 24666128; PubMed – as supplied by publisher].




2013 Publications

Moritz AE, Foster JD, Gorentla BK, Mazei-Robison MS, Yang JW, Sitte HH, Blakely RD, Vaughan RA. Phosphorylation of dopamine transporter serine 7 modulates cocaine analog binding. J Biol Chem, 2013 Jan 4;288(1):20-32, [PMID: 23161550; PMCID: PMC3537014].


Baganz NL, Blakely RD. A dialogue between the immune system and brain, spoken in the language of serotonin. ACS Chem Neurosci, 2013 Jan 16;4(1):48-63, [PMID: 23336044; PMCID: PMC3547518].


Parikh V, St. Peters M, Blakely RD, Sarter M. The presynaptic choline transporter imposes limits on sustained cortical acetylcholine release and attention. J Neurosci, February 6, 2013, 33(6):2326-2337, [PMID: 23392663; PMCID: PMC3711270].


Paolone G, Mallory CS, Koshy Cherian A, Miller TR, Blakely RD, Sarter M. Monitoring cholinergic activity during attentional performance in mice heterozygous for the choline transporter: A model of cholinergic capacity limits. Neuropharmacology, 2013 Aug 16; 75C:274-285, [PMID: 23958450].


Campbell NG, Zhu CB, Lindler KM, Yaspan BL, Kistner-Griffin E; NIH ARRA Consortium, Hewlett WA, Tate CG, Blakely RD, Sutcliffe JS. Rare coding variants of the adenosine A3 receptor are increased in autism: on the trail of the serotonin transporter regulome. Mol Autism. 2013 Aug 16;4(1)28, [PMID: 23953133].


Kerr TM, Muller CL, Miah M, Jetter CS, Pfeiffer R, Shah C, Baganz N, Anderson GM, Crawley JN, Sutcliffe JS, Blakely RD, Veenstra-Vanderweele J. Genetic background modulates phenotypes of serotonin transporter Ala56 knock-in mice. Mol Autism. 2013 Oct 1; 4(1):35, [PMID: 24083388].


Ye R, Carneiro AM, Airey D, Sanders-Bush E, Williams RW, Lu L, Wang J, Zhang B, Blakely RD. Evaluation of heritable determinants of blood and brain serotonin homeostasis using recombinant inbred mice. Genes Brain Behav. 2013 Oct 4. doi:10.1111.gbb.12092, Epub ahead of print, [PMID 24102824].


Dong Y, Dani JA, Blakely RD. Choline transporter hemizygosity results in diminished basal extracellular dopamine levels in nucleus accumbens and blunts dopamine elevations following cocaine or nicotine. Biochem Pharmacol. 2013 Oct 15; 86(8):1084-8, [PMID: 23939187].



2010 Publications Page

2009 Publications Page