Blakely Lab

The Blakely Lab

The Blakely Lab: 2011 Publications



Tomlinson ID, Iwamoto H, Blakely RD, Rosenthal SJ. Biotin tethered homotryptamine derivatives: high affinity probes of the human serotonin transporter (hSERT). Bioorg Med Chem Lett. 2011 Mar 15; 21(6):1678-82; [PMID: 21334895; PMCID: 3070488].


Thompson BJ, Jessen T, Henry LK, Field JR, Gamble KL, Gresch PJ, Carneiro AM, Horton RE, Chisnell PJ, Belova Y, McMahon DG, Daws LC, Blakely RD. Transgenic elimination of high-affinity antidepressant and cocaine sensitivity in the presynaptic serotonin transporter. Proc Natl Acad Sci U S A. 2011 Mar 1; 108(9):3785-90; [PMID: 21282638; PMCID: 3048100].


Rasul A, El-Nour H, Blakely RD, Lonne-Rahm SB, Forsberg J, Johansson B, Theodorsson E, Nordlind K. Effect of chronic mild stress on serotonergic markers in the skin and brain of the NC/Nga atopic-like mouse strain. Arch Dermatol Res. 2011 Nov; 303(9):625-33. doi: 10.1007/s00403-011-1138-8. Epub 2011 Mar 15; [PMID: 21400247].


Kohli U, Hahn MK, English BA, Sofowora GG, Muszkat M, Li C, Blakely RD, Stein CM, Kurnik D. Genetic variation in the presynaptic norepinephrine transporter is associated with blood pressure responses to exercise in healthy humans. Pharmacogenet Genomics. 2011 Apr; 21(4):171-8; [PMID: 21412203; PMCID: 3065933]


Bonnin A, Goeden N, Chen K, Wilson ML, King J, Shih JC, Blakely RD, Deneris ES, Levitt P. A transient placental source of serotonin for the fetal forebrain. Nature. 2011 Apr 21; 472(7343):347-50; [PMID: 21512572; PMCID: 3084180].


Kovtun O, Tomlinson ID, Sakrikar DS, Chang JC, Blakely RD, Rosenthal SJ. Visualization of the cocaine-sensitive dopamine transporter with ligand-conjugated quantum dots. ACS Chem Neurosci. 2011 Jul 20; 2(7):370-8. Epub 2011 Apr 26. [PMID: 22816024; PMCID: 3369746].


Blakely RD, Veenstra-VanderWeele J. Genetic indeterminism, the 5-HTTLPR, and the paths forward in neuropsychiatric genetics. Arch Gen Psychiatry. 2011 May; 68(5):457-8; [PMID: 21536974; PMCID: 3686479].


Zhu CB, Lindler KM, Campbell NG, Sutcliffe JS, Hewlett WA, Blakely RD. Colocalization and regulated physical association of presynaptic serotonin transporters with A3 adenosine receptors. Mol Pharmacol. 2011 Sep; 80(3):458-65. Epub 2011 Jun 24; [PMID: 21705486; PMCID: 3164334].


Henry LK, Iwamoto H, Field JR, Kaufmann K, Dawson ES, Jacobs MT, Adams C, Felts B, Zdravkovic I, Armstrong V, Combs S, Solis E, Rudnick G, Noskov SY, DeFelice LJ, Meiler J, Blakely RD. A conserved asparagine residue in transmembrane segment 1 (TM1) of serotonin transporter dictates chloride-coupled neurotransmitter transport. J Biol Chem. 2011 Sep 2; 286(35):30823-36. Epub 2011 Jul 5. [PMID: 21730057; PMCID: 3162443].


Ye R, Blakely RD. Natural and engineered coding variation in antidepressant-sensitive serotonin transporters. Neuroscience. 2011 Dec 1;197:28-36. Epub 2011 Aug 28; [PMID: 21893166, PMCID: 3850749].


Erickson SL, Gandhi AR, Asafu-Adjei JK, Sampson AR, Miner L, Blakely RD, Sesack SR. Chronic desipramine treatment alters tyrosine hydroxylase but not norepinephrine transporter immunoreactivity in norepinephrine axons in the rat prefrontal cortex. Int J Neuropsychopharmacol. 2011 Oct; 14(9):1219-32. Epub 2011 Jan 6; [PMID: 21208501; PMCID: 3117082].


Chang JC, Tomlinson ID, Warnement MR, Iwamoto H, DeFelice LJ, Blakely RD, Rosenthal SJ. A fluorescence displacement assay for antidepressant drug discovery based on ligand-conjugated quantum dots. J Am Chem Soc. 2011 Nov 9; 133(44):17528-31. Epub 2011 Oct 17; [PMID: 21970724; PMCID: 3235909].


Combs S, Kaufmann K, Field JR, Blakely RD, Meiler J. Y95 and e444 interaction required for high-affinity s-citalopram binding in the human serotonin transporter. ACS Chem Neurosci. 2011 Feb 16; 2(2):75-81. Epub 2010 Oct 27; [PMID: 22778858; PMCID: 3369724].