Jack P. Kennedy (Phil)

Graduate Student

     

      B.S. Chemistry, San Diego State University, 2005
     

Phone: (615) 322-8662
Fax: (615) 322-8577
Email: jack.p.kennedy@vanderbilt.edu
Location: 12475 MRB IV (Langford)

 

Biosketch and Research Interests

Organic chemistry, total synthesis, medicinal chemistry and drug discovery.

 

Selected Publications

Kennedy, J. Phillip; Brogan, John T.; Lindsley, Craig W.   Progress toward the synthesis of piperazimycin A: exploration of the synthesis of gama -hydroxy and gama -chloropiperazic acids.    Tetrahedron Letters  (2008),  49(26),  4116-4118.

 

Michelle Lewis, L.; Sheffler, Douglas; Williams, Richard; Bridges, Thomas M.; Kennedy, J. Phillip; Brogan, J. T.; Mulder, Matthew J.; Williams, Lyndsey; Nalywajko, Natalia T.; Niswender, Colleen M.; Weaver, Charles D.; Conn, P. Jeffrey; Lindsley, Craig W.   Synthesis and SAR of selective muscarinic acetylcholine receptor subtype 1 (M1 mAChR) antagonists.    Bioorganic & Medicinal Chemistry Letters  (2008),  18(3),  885-890.

 

Kennedy, J. Phillip; Williams, Lyndsey; Bridges, Thomas M.; Daniels, R. Nathan; Weaver, David; Lindsley, Craig W.   Application of Combinatorial Chemistry Science on Modern Drug Discovery.    Journal of Combinatorial Chemistry  (2008),  10(3),  345-354.

 

Kennedy, J. Phillip; Lindlsey, Craig W.   Molecule of the month.    Current Topics in Medicinal Chemistry (Sharjah, United Arab Emirates)  (2007),  7(12),  1248.

 

McAllister, Laura A.; Hixon, Mark S.; Kennedy, Jack P.; Dickerson, Tobin J.; Janda, Kim D.   Superactivation of the Botulinum Neurotoxin Serotype A Light Chain Metalloprotease: A New Wrinkle in Botulinum Neurotoxin.    Journal of the American Chemical Society  (2006),  128(13),  4176-4177.

 

Boldt, Grant E.; Kennedy, Jack P.; Hixon, Mark S.; McAllister, Laura A.; Barbieri, Joseph T.; Tzipori, Saul; Janda, Kim D.   Synthesis, Characterization and Development of a High-Throughput Methodology for the Discovery of Botulinum Neurotoxin A Inhibitors.    Journal of Combinatorial Chemistry  (2006),  8(4),  513-521.

 

Silvaggi, Nicholas R.; Boldt, Grant E.; Hixon, Mark S.; Kennedy, Jack P.; Tzipori, Saul; Janda, Kim D.; Allen, Karen N.   Structures of Clostridium botulinum Neurotoxin Serotype A Light Chain Complexed with Small-Molecule Inhibitors Highlight Active-Site Flexibility.    Chemistry & Biology (Cambridge, MA, United States)  (2007),  14(5),  533-542.

 

Boldt, Grant E.; Kennedy, Jack P.; Janda, Kim D.   Identification of a Potent Botulinum Neurotoxin A Protease Inhibitor Using in Situ Lead Identification Chemistry.    Organic Letters  (2006),  8(8),  1729-1732.