Autumn 2007 - How to Build a Stronger Heart

Vanderbilt stem cell expert Antonis Hatzopoulos, Ph.D.  In the background, intravascular ultrasound images of the coronary artery, courtesy of Matthew O'Donnell, Ph.D., University of Washington College of Engineering.The image was created by O’Donnell’s group at the University of Michigan Biomedical Engineering Department, in conjunction with EndoSonics, now Volcano Corporation.Cardiac regeneration

Damaged hearts one day may be renewed, thanks to an experimental “regenerative medicine” technique that uses stem cells harvested from the patient’s bone marrow. The goal is to get the right cells to the right place, and get them to do the right thing -- turn into new heart muscle.  read more


Davis NwankwoOff tempo

Nearly every minute of every day, an American is killed by sudden cardiac death. With the help of genetic screening and pharmacogenomics, scientists are finding ways to identify—and prevent—the errant heartbeat before it takes another life.  read more


Red blood cells trapped in a web of fibrin threads form a clot.Too much clot

People with obesity and diabetes are more likely than others to die of heart attacks and strokes. The culprit is thrombosis—their blood tends to clot more easily. Racing before the rising tide of these twin epidemics, Vanderbilt scientists are trying to find out why.  read more


The cholesterol conundrum

Cholesterol is either “bad” or “good” depending upon the company it keeps; what’s transporting it around the body. Here’s the latest on efforts to keep it—and you—out of harm’s way.  read article

The people's agenda

Elizabeth Nabel, M.D., director of the National Heart, Lung, and Blood Institute, and Rose Marie Robertson, M.D., chief science officer of the American Heart Association and professor of Medicine at Vanderbilt, discuss how public-private partnerships can advance the fight against heart disease and stroke.  read article

Also in this Issue:

Guest Editorial - Douglas E. Vaughan, M.D.

Stem cell pioneer

Babies at risk

When medication is not enough

Eugene Braunwald: Maestro Of American Cardiology

New views of heart disease

How to tell if you’re at risk

The importance of knowing your numbers

Two sides of omentum

Science of the soldier’s heart

From auto parts to cell parts