The cholesterol conundrum  pg. 4

Interactions between foam cells and white blood cells trigger a chronic inflammatory process.  Smooth muscle cells migrate to the arterial wall, proliferate and secrete proteins that form a fibrous plaque.  As the foam cells die, the plaque weakens and can rupture.  Platelets are attracted to the site of the rupture, and can quickly form a clot that blocks the vessel completely.
Illustrations by Dominic Doyle.

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