In the not-too-distant future, cells taken from patients with diabetes will be “re-programmed” in the laboratory to create new insulin-producing beta cells that potentially can cure their disease. It sounds like science fiction, but researchers are quickly learning the genetic keys to this developmental path. read article
Sections
The fine art of brain development
It takes more than a hammer and chisel to shape the grandest sculpture of them all, the human brain. At least half the genome (10,000 genes or more) may be required. Equally surprising: development never stops. The living brain never achieves a “final” form. read article
The lub-dub of a healthy heart
Valves in action give the heart its characteristic lub-dub sound. When they fail, the results can be fatal. What if scientists could build replacement heart valves from patients’ own tissues? The hypothesis may be “outrageous,” but according to Vanderbilt researchers, it just might work. read article
Trudi Schüpbach and Eric Wieschaus: A shared passion for nature’s truth
Princeton developmental biologists Eric Wieschaus and Trudi Schüpbach, who are husband and wife, have shared more than their work in the laboratory and a home life raising three daughters – they are of one mind when it comes to preserving the “purity” of scientific truth. read article
Internationally known reproductive biologist S.K. Dey advocates “a million scientists march” on Washington to sound the alarm about regulatory impediments and dwindling research support that are slowing the pace of progress. If the situation doesn’t improve, he warns, scientists may become “an endangered species.” read article
Nature’s operating system – an essay by Christopher V.E. Wright, D.Phil.
An essay by Christopher V.E. Wright, D.Phil., director of the Vanderbilt University Program in Developmental Biology read article
The march of biomedical science during the past century owes much to a handful of humble creatures, notably the fruit fly, the frog, the worm, the mouse – and recently the zebrafish.
The common fruit fly, Drosophila melanogaster, is one of the most-studied organisms on earth, largely because it matures from fertilized egg to adult in a matter of days and is easy to grow and manipulate. read article
The brain carefully conceals its lopsided nature. While it appears outwardly symmetrical, certain functions, like language, are localized preferentially to one side of the brain or the other.
“And because the brain and mind are inextricably linked – the mind is derived from the function of the brain – presumably there are also a number of structural asymmetries as well,” says Josh Gamse, Ph.D., assistant professor of Biological Sciences and Cell & Developmental Biology at Vanderbilt. read article
A unique program at Vanderbilt University connects high school students with scientists. For one graduate, it was a life-changing experience. read article
