Introduction
to Proteomics: Tools for the New Biology
Published by Humana
Press.
Available from several online distributors.
From the back cover:
"
introduces the science of proteomics by spelling out
the basics of how one analyzes proteins and proteomes, and just
how these approaches are then employed to investigate their roles
in living systems. He explains the key concepts of proteomics,
how the analytical instrumentation works, what data mining and
other software tools do, and how these tools can be integrated
to study proteomes. Also discussed are how protein and peptide
separation techniques are applied in proteomics, how mass spectrometry
is used to identify proteins, and how data analysis software enables
protein identification and the mapping of modifications. In addition,
there are proteomic approaches for analyzing differential protein
expression, characterizing proteomic diversity, and dissecting
protein-protein interactions and networks."
From the Preface:
"
This book is an introduction to the new field of proteomics.
It is intended to describe how proteins and proteomes can be analyzed
and studied. Despite widespread, growing interest in proteomics,
an understanding of proteomics tools and technologies are only
slowly penetrating the research community at large. This book
addresses the need to introduce biologists to new tools and approaches.
This book is both for students of biology and for experienced,
practicing biologists. Any student who has taken a graduate level
biochemistry course should be able to take from this book a reasonable
understanding of what proteomics is all about and how it is practiced
"
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