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WC Lee, et. al. JBC, 2008 Lee WC, Reniere ML, Skaar EP, Murphy ME. Ruffling of metalloporphyrins bound to IsdG and IsdI, two heme degrading enzymes in Staphylococcus aureus. J Biol Chem. 2008 Aug 19. [Epub ahead of print]
Molecular Microbiology July 2008 Reniere ML, Skaar EP. Staphylococcus aureus haem oxygenases are differentially regulated by iron and haem. Mol Microbiol. 2008 Sep;69(5):1304-15. Epub 2008 Jul 10.
J. Bact. 03-07-08 Stauff DL, Bagaley D, Torres VJ, Joyce R, Anderson KL, Kuechenmeister L, Dunman PM, Skaar EP. Staphylococcus aureus HrtA is an ATPase required for protection against heme toxicity and prevention of a transcriptional heme-stress response. J Bacteriol. 2008 Mar 7 [Epub ahead of print]
JBC 02-15-08 Corbin BD, Seeley EH, Raab A, Feldmann J, Miller MR, Torres VJ, Anderson KL, Dattilo BM, Dunman PM, Gerads R, Caprioli RM, Nacken W, Chazin WJ, Skaar EP. Metal chelation and inhibition of bacterial growth in tissue abscesses. Science. 2008 Feb 15;319(5865):962-5.
JBC 01-01-08 Palazzolo-Ballance AM, Reniere ML, Braughton KR, Sturdevant DE, Otto M, Kreiswirth BN, Skaar EP, DeLeo FR. Neutrophil microbicides induce a pathogen survival response in community-associated methicillin-resistant Staphylococcus aureus. J Immunol. 2008 Jan 1;180(1):500-9.
JBC 09-07-07 Stauff DL, Torres VJ, Skaar EP. Signaling and DNA-binding Activities of the Staphylococcus aureus HssR-HssS Two-component System Required for Heme Sensing.J Biol Chem. 2007 Sep 7;282(36):26111-21. Epub 2007 Jul 16.
Torres, V.J., Stauff, D.L., Pishchany, G., Bezbradica, J.S., Gordy, L.E., Iturregui, J., Anderson, K.L,Dunman, P.M., Joyce, S., Skaar, E.P. A Staphylococcus aureus regulatory system that responds to host heme and modulates virulence. Cell Host and Microbe. 2007, Vol 1, 109-119
Reniere, ML, Torres, VJ, Skaar, EP. Intracellular metalloporphyrin metabolism in Staphylococcus aureus. Biometals, , , 2007.
Friedman, DB, Stauff, DL, Pishchany, G, Whitwell, CW, Torres, VJ, Skaar, EP. Staphylococcus aureus Redirects Central Metabolism to Increase Iron Availability. PLoS Pathog, 2(8), , 2006.
Skaar, EP, Gaspar, AH, Schneewind, O. Bacillus anthracis IsdG, a heme-degrading monooxygenase. J Bacteriol, 188(3), 1071-80, 2006.
Torres VJ, Pishchany G, Humayun M, Schneewind O, Skaar EP, Staphylococcus aureus IsdB is a Hemoglobin Receptor Required for Heme-Iron Utilization. J Bacteriol., [Epub ahead of print], 2006 Oct 13.
Skaar, EP, Lecuyer, B, Lenich, AG, Lazio, MP, Perkins-Balding, D, Seifert, HS, Karls, AC. Analysis of the Piv recombinase-related gene family of Neisseria gonorrhoeae. J Bacteriol, 187(4), 1276-86, 2005.
Wu, R, Skaar, EP, Zhang, R, Joachimiak, G, Gornicki, P, Schneewind, O, Joachimiak, A. Staphylococcus aureus IsdG and IsdI, heme-degrading enzymes with structural similarity to monooxygenases. J Biol Chem, 280(4), 2840-6, 2005.
Skaar, EP, Gaspar, AH, Schneewind, O. IsdG and IsdI, heme-degrading enzymes in the cytoplasm of Staphylococcus aureus. J Biol Chem, 279(1), 436-43, 2004.
Skaar, EP, Humayun, M, Bae, T, DeBord, KL, Schneewind, O. Iron-source preference of Staphylococcus aureus infections. Science, 305(5690), 1626-8, 2004.
Skaar, EP, Schneewind, O. Iron-regulated surface determinants (Isd) of Staphylococcus aureus: stealing iron from heme. Microbes Infect, 6(4), 390-7, 2004.
Kline, KA, Sechman, EV, Skaar, EP, Seifert, HS. Recombination, repair and replication in the pathogenic Neisseriae: the 3 R's of molecular genetics of two human-specific bacterial pathogens. Mol Microbiol, 50(1), 3-13, 2003.
Mazmanian, SK, Skaar, EP, Gaspar, AH, Humayun, M, Gornicki, P, Jelenska, J, Joachmiak, A, Missiakas, DM, Schneewind, O. Passage of heme-iron across the envelope of Staphylococcus aureus. Science, 299(5608), 906-9, 2003.
Hickman, JW, Barber, RD, Skaar, EP, Donohue, TJ. Link between the membrane-bound pyridine nucleotide transhydrogenase and glutathione-dependent processes in Rhodobacter sphaeroides. J Bacteriol, 184(2), 400-9, 2002.
Skaar, EP, Lazio, MP, Seifert, HS. Roles of the recJ and recN genes in homologous recombination and DNA repair pathways of Neisseria gonorrhoeae. J Bacteriol, 184(4), 919-27, 2002.
Skaar, EP, Seifert, HS. The misidentification of bacterial genes as human cDNAs: was the human D-1 tumor antigen gene acquired from bacteria. Genomics, 79(5), 625-7, 2002.
Skaar, EP, Tobiason, DM, Quick, J, Judd, RC, Weissbach, H, Etienne, F, Brot, N, Seifert, HS. The outer membrane localization of the Neisseria gonorrhoeae MsrA/B is involved in survival against reactive oxygen species. Proc Natl Acad Sci U S A, 99(15), 10108-13, 2002.

Press Releases

IAAC presents Eric Skaar with the Youung Investigator Award
http://www.mc.vanderbilt.edu/reporter/index.html?ID=6154
http://www.searlescholars.net/people/2006/skaar.html
http://www.webmd.com/content/article/94/102585.htm?z=1728_00000_1000_nb_06
http://jama.ama-assn.org/cgi/content/full/292/17/2071
http://www.bwfund.org/programs/infectious_disease/pathogenesis_grant_recipients.html
Click on a link to view press releases regarding research and publications in the Skaar Lab, click on an image to go directly to the PDF or click on text to go to the NIH PubMed page.

Publications and Press Releases

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