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The Van Kaer Laboratory


Martin, W.D., Hicks, G.G., Mendiratta, S.K., Leva, H.I., Ruley, H.E., and Van Kaer, L. (1996). H2-M mutant mice are defective in the peptide loading of class II molecules, antigen presentation, and T cell repertoire selection. Cell84, 543-550.

Mendiratta, S.K., Martin, W.D., Hong, S., Boesteanu, A., Joyce, S., and Van Kaer, L. (1997). CD1d1 mutant mice are deficient in natural T cells that promptly produce IL-4. Immunity 6, 469-477.

Hong, S., Scherer, D.C., Singh, N., Mendiratta, S.K., Serizawa, I., Koezuka, Y., and Van Kaer, L. (1999). Lipid antigen presentation in the immune system: lessons learned from CD1d knockout mice. Immunol. Rev. 169, 31-44.

Singh, N., Hong, S., Scherer, D.C., Serizawa, I., Burdin, N., Kronenberg, M., Koezuka, Y., and Van Kaer, L. (1999). Cutting Edge: Activation of NK T cells by CD1d and a-galactosylceramide directs conventional T cells to the acquisition of a Th2 phenotype. J. Immunol. 163, 2373-2377.

Grandea, A.G. III, Golovina, T.N., Hamilton, S.E., Sriram, V., Spies, T., Brutkiewicz, R.R., Harty, J.H., Eisenlohr, L., and Van Kaer, L. (2000). Impaired assembly yet normal trafficking of MHC class I molecules in Tapasin mutant mice. Immunity 13, 213-222.

Grandea, A.G. III, and Van Kaer, L. (2001). Tapasin: an ER chaperone that controls MHC class I assembly with peptide. Trends Immunol. 22, 194-199.

Van Kaer, L. (2001). Accessory proteins that control the assembly of MHC molecules with peptides. Immunol. Res. 23-2/3, 205-214.

Hong, S., Wilson, M.T., Serizawa, I., Wu, L., Singh, N., Naidenko, O., Miura, T., Haba, T., Scherer, D.C., Wei, J., Kronenberg, M., Koezuka, Y., and Van Kaer, L. (2001). The natural killer T-cell ligand a-galactosylceramide prevents autoimmune diabetes in non-obese diabetic mice. Nat. Med. 7, 1052-1056.

Singh, A.K., Wilson, M.T., Hong, S., Olivares-Villagomez, D., Du, C., Stanic A.K., Koezuka, Y., Joyce, S., Sriram, S., and Van Kaer, L. (2001). Natural killer T cell activation protects mice against experimental autoimmune encephalomyelitis. J. Exp. Med., in press.



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