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The Van Kaer Laboratory


1. Pamer, E., and Cresswell, P. (1998). Mechanismsof MHC class I-restricted antigen processing. Annu. Rev. Immunol.16, 323-358.

2. Rock, K.L., and Goldberg, A.L. (1999). Degradationof cell proteins and the generation of MHC class I-presented peptides.Annu. Rev. Immunol. 17, 739-779.

3. Grandea, A.G., 3rd, Androlewicz, M.J.,Athwal, R.S., Geraghty, D.E., and Spies, T. (1995). Dependence of peptidebinding by MHC class I molecules on their interaction with TAP. Science270, 105-108.

4. Ortmann, B., Copeman, J., Lehner, P.J., Sadasivan,B., Herberg, J.A., Grandea, A.G., Riddell, S.R., Tampe, R., Spies, T.,Trowsdale, J., and Cresswell, P. (1997). A critical role for tapasin inthe assembly and function of multimeric MHC class I-TAP complexes. Science277, 1306-1309.

5. Watts, C. (1997). Capture and processing of exogenous antigens for presentation on MHC molecules. Annu. Rev. Immunol.15, 821-850.

6. Pieters, J. (1997). MHC class II restricted antigen presentation. Curr. Opin. Immunol. 9, 89-96.

7. Kropshofer, H., Hammerling, G.J., and Vogt, A.B.(1997). How HLA-DM edits the MHC class II peptide repertoire: survivalof the fittest? Immunol. Today 18, 77-82.

8. Martin, W.D., Hicks, G.G., Mendiratta, S.K., Leva,H.I., Ruley, H.E., and Van Kaer, L. (1996). H2-M mutant mice aredefective in the peptide loading of class II molecules, antigen presentation,and T cell repertoire selection. Cell 84, 543-550.

9. Mendiratta, S.K., Kovalik, J.-P., Hong, S., Singh,N., Martin, W.D., and Van Kaer, L. (1999). Peptide dependency of alloreactiveCD4+ T cell responses. Int. Immunol. 11, 351-360.

10. Sebzda, E., Mariathasan, S., Ohteki, T., Jones,R., Bachmann, M.F., and Ohashi, P.S. (1999). Selection of the T cell repertoire.Annu. Rev. Immunol. 17, 829-874.

11. Jameson, S.C., and Bevan, M.J. (1998). T-cellselection. Curr. Opin. Immunol. 10, 214-219.

12. Singh, N., and Van Kaer, L. (1999). Unexpectedreactivities of T cells selected by a single MHC-peptide ligand. J.Immunol., in press.

13. Porcelli, S.A., and Modlin, R.L. (1999). TheCD1 system: antigen-presenting molecules for T cell recognition of lipidsand glycolipids. Annu. Rev. Immunol. 17, 297-329.

14. Bendelac, A., Rivera, M.N., Park, S.H., and Roark, J.H. (1997). Mouse CD1-specific NK1 T cells: development, specificity,and function. Annu. Rev. Immunol. 15, 535-562.

15. Hong, S., Scherer, D.C., Singh, N., Mendiratta,S.K., Serizawa, I., Koezuka, Y., and Van Kaer, L. (1999). Lipid antigenpresentation in the immune system: lessons learned from CD1d knockout mice.Immunol. Rev. 169, 31-44.

16. Mendiratta, S.K., Martin, W.D., Hong, S., Boesteanu, A., Joyce, S., and Van Kaer, L. (1997). CD1d1 mutant mice are deficientin natural T cells that promptly produce IL-4. Immunity 6, 469-477.

17. Singh, N., Hong, S., Scherer, D.C., Serizawa,I., Burdin, N., Kronenberg, M., Koezuka, Y., and Van Kaer, L. (1999). CuttingEdge: Activation of NK T cells by CD1d and a-galactosylceramide directs conventional T cells to the acquisition of a Th2 phenotype. J. Immunol. 163, 2373-2377.



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