H. Charles Manning, Ph.D.
Neurosurgery, Biomedical Engineering
molecular imaging, optical imaging, PET, apoptosis, treatment response, small molecule discovery
Our multi-disciplinary research program involves the development, validation, and translation of non-invasive molecular imaging metrics to assess disease progression and response to therapy. Projects within our program emphasize molecular imaging of cancer and other diseases, and notably imaging-based assessment of response to pharmaceuticals in colorectal and breast cancer. We are actively engaged in advancing novel methods to image molecular events in both humans and animal models that include receptor expression, proliferation, angiogenesis, and apoptosis. Among these methods include validation of existing imaging probes for novel applications, as well as high-throughput small-molecule discovery to develop novel imaging compounds.
Last updated on 2009-10-14