March 7, 2013

Surgery Research Collaborative to discuss impact of increased lipid deposition in liver, Tuesday, March 12

As part of the Surgery Research Collaborative speaker series, Charles Robb Flynn, Ph.D., assistant professor of Surgery, will present, “New molecular discriminants of nonalcoholic steatohepatitis and steatosis revealed by high-throughput profiling,” March 12 at 5 p.m. at the University Club.

In collaboration with Naji Abumrad, M.D., John L. Sawyers Professor of Surgery and Chair of Surgery, Flynn’s research focuses on the prevalence of increased lipid deposition in the liver, which has increased along with the incidence of obesity. Both nonalcoholic fatty liver disease (NAFLD) and nonalcoholic steatohepatitis (NASH) are associated with insulin resistance and hepatic dysfunction.

Through their efforts, they aim to identify new molecular discriminants of NASH that may one day serve as diagnostic or therapeutic targets for this increasingly prevalent disease.

The Department of Surgery Research Collaborative was developed to provide synergy between the basic sciences and clinical research as a means of enhancing research opportunities within the Section of Surgical Sciences.

The collaborative hosts open meetings the second Tuesday of every month in the Hermitage Room of the University Club, offering opportunities for informal discussion as well as presentations from both the basic sciences and translational research. Section faculty, residents, fellows and staff are invited and strongly encouraged to attend.

Refreshments will be provided.