September 3, 2013

Pittsburgh's Pei Tang, Ph.D., to lecture on "Atomic View of Anesthetic Action," Thursday, Sept. 5

The Vanderbilt Department of Anesthesiology welcomes Pei Tang, PhD, professor of Anesthesiology, Pharmacology & Chemical Biology, and Computational & Systems Biology at the University of Pittsburgh School of Medicine, for a special guest lecture. Tang’s talk, “Atomic View of Anesthetic Action” is Thursday, Sept. 5, at 3:30 p.m. in 512 Light Hall.

Tang is one of the world’s leading experts on the molecular mechanisms of general anesthesia, a century-long medical practice that remains undefined functionally at the molecular and cellular level. Her investigations have focused on the molecular nature of general anesthetic interaction with pentameric ligand gated ion channels (pLGICs). She has combined the use of various biophysical approaches, notably the state-of-the-art high-resolution nuclear magnetic resonance (NMR) spectroscopy, X-ray crystallography, and molecular dynamics simulations, to elucidate general anesthetic effects on the structures and dynamics of pLGICs.

Tang has published more than 80 peer-reviewed original papers in high impact journals. In addition, she has published more than 120 peer-reviewed abstracts in meeting proceedings and society journals (e.g., Anesthesiology, Biophysical Journal) since 1993. She has spoken at the Association of University Anesthesiologists meeting, the International Conference on Molecular and Basic Mechanisms of Anesthesia and an international workshop on anesthetic and alcohol mechanisms. Tang has served as a reviewer for NIH study sections and numerous journals, including Anesthesiology, Nature Communications, Structure, Molecular Pharmacology, and Biophysical Journal.

Tang received her Ph.D. in chemistry from the State University of New York at Stony Brook and has done post-doctoral work at the University of California at Berkeley and Lawrence Berkeley National Laboratory. She joined the faculty at the University of Pittsburgh School of Medicine in 1995.