Robert M. Kessler, M.D.

Position: Professor

Department: Radiology & Radiological Sciences

Lab Url: N/A

Email: robert.kessler@vanderbilt.edu

Office Address: 1161 21st Avenue, South
Office Address2: MCN CCC-1121
Nashville , TN 37232-2675
Phone :(615) 343-3938
Fax: 615-322-3764

Lab Address: 1268-B RRB


Robert M. Kessler's picture
  Robert M. Kessler, M.D.
Patient Care Specialty
Neuroradiology, cortical and limbic dopaminergic neurotransmission, attention deficit disorder, depression, psychostimulant drug abuse, schizophrenia

Research Specialty
Cerebral neurotransmission and energy metabolism and their relationship to psychiatric and neurological disorders

Publications
Rieck, Richard W, Ansari, M S, Whetsell, William O, Deutch, Ariel Y, Kessler, Robert M. Distribution of dopamine D2-like receptors in the human thalamus: autoradiographic and PET studies. Neuropsychopharmacology, 29(2), 362-72, 2004

Kessler, Robert M. Imaging methods for evaluating brain function in man. Neurobiol Aging, 24 Suppl 1, S21-35; discussion S37-9, 2003

Garland, Emily M, Anderson, James C, Black, Bonnie K, Kessler, Robert M, Konrad, Peter E, Robertson, David. No increased herniation of the cerebellar tonsils in a group of patients with orthostatic intolerance. Clin Auton Res, 12(6), 472-6, 2002

Kessler RM, Meltzer HY. Regional selectivity in clozapine treatment?. Amer J Psychiatry, 159(6), 1064-1065, 2002

Fakhoury, T, Abou-Khalil, B, Kessler, R M. Limbic encephalitis and hyperactive foci on PET scan. Seizure, 8(7), 427-31, 1999

West, J, Fitzpatrick, J M, Wang, M Y, Dawant, B M, Maurer, C R, Kessler, R M, Maciunas, R J. Retrospective intermodality registration techniques for images of the head: surface-based versus volume-based. IEEE Trans Med Imaging, 18(2), 144-50, 1999

West, J, Fitzpatrick, J M, Wang, M Y, Dawant, B M, Maurer, C R, Kessler, R M, Maciunas, R J, Barillot, C, Lemoine, D, Collignon, A, Maes, F, Suetens, P, Vandermeulen, D, van den Elsen, P A, Napel, S, Sumanaweera, T S, Harkness, B, Hemler, P F, Hill, D L, Hawkes, D J, Studholme, C, Maintz, J B, Viergever, M A, Malandain, G, Woods, R P. Comparison and evaluation of retrospective intermodality brain image registration techniques. J Comput Assist Tomogr, 21(4), 554-66, 1997

Delbeke, D, Lawrence, S K, Abou-Khalil, B W, Blumenkopf, B, Kessler, R M. Postsurgical outcome of patients with uncontrolled complex partial seizures and temporal lobe hypometabolism on 18FDG-positron emission tomography. Invest Radiol, 31(5), 261-6, 1996

Abou-Khalil, B, Fakhoury, T, Jennings, M, Moots, P, Warner, J, Kessler, R M. Inhibitory motor seizures: correlation with centroparietal structural and functional abnormalities. Acta Neurol Scand, 91(2), 103-8, 1995

Delbeke, D, Meyerowitz, C, Lapidus, R L, Maciunas, R J, Jennings, M T, Moots, P L, Kessler, R M. Optimal cutoff levels of F-18 fluorodeoxyglucose uptake in the differentiation of low-grade from high-grade brain tumors with PET. Radiology, 195(1), 47-52, 1995

Martin, W H, Delbeke, D, Patton, J A, Hendrix, B, Weinfeld, Z, Ohana, I, Kessler, R M, Sandler, M P. FDG-SPECT: correlation with FDG-PET. J Nucl Med, 36(6), 988-95, 1995

Pierce, M A, Johnson, M D, Maciunas, R J, Murray, M J, Allen, G S, Harbison, M A, Creasy, J L, Kessler, R M. Evaluating contrast-enhancing brain lesions in patients with AIDS by using positron emission tomography. Ann Intern Med, 123(8), 594-8, 1995

Votaw, J R, Ansari, M S, Mason, N S, Schmidt, D, de Paulis, T, Holburn, G, Clanton, J A, Votaw, D B, Manning, R G, Kessler, R M. Dosimetry of iodine-123-epidepride: a dopamine D2 receptor ligand. J Nucl Med, 36(7), 1316-21, 1995

Ge, Y, Fitzpatrick, J M, Votaw, J R, Gadamsetty, S, Maciunas, R J, Kessler, R M, Margolin, R A. Retrospective registration of PET and MR brain images: an algorithm and its stereotactic validation. J Comput Assist Tomogr, 18(5), 800-10, 1994

Schmidt, D E, Votaw, J R, Kessler, R M, de Paulis, T. Aromatic and amine substituent effects on the apparent lipophilicities of N-[(2-pyrrolidinyl)methyl]-substituted benzamides. J Pharm Sci, 83(3), 305-15, 1994

Delbeke, D, Lorenz, C H, Votaw, J R, Silveira, S T, Frist, W H, Atkinson, J B, Kessler, R M, Sandler, M P. Estimation of left ventricular mass and infarct size from nitrogen-13-ammonia PET images based on pathological examination of explanted human hearts. J Nucl Med, 34(5), 826-33, 1993

Hoff, S J, Stewart, J R, Frist, W H, Atkinson, J B, Kronenberg, M W, Votaw, J, Kessler, R M, Sandler, M P. Noninvasive detection of acute rejection in a new experimental model of heart transplantation. Ann Thorac Surg, 56(5), 1074-7, 1993

Kessler, R M, Votaw, J R, Schmidt, D E, Ansari, M S, Holdeman, K P, de Paulis, T, Clanton, J A, Pfeffer, R, Manning, R G, Ebert, M H. High affinity dopamine D2 receptor radioligands. 3. [123I] and [125I]epidepride: in vivo studies in rhesus monkey brain and comparison with in vitro pharmacokinetics in rat brain. Life Sci, 53(3), 241-50, 1993

Kessler, R M, Votaw, J R, de Paulis, T, Bingham, D R, Ansari, M S, Mason, N S, Holburn, G, Schmidt, D E, Votaw, D B, Manning, R G. Evaluation of 5-[18F]fluoropropylepidepride as a potential PET radioligand for imaging dopamine D2 receptors. Synapse, 15(3), 169-76, 1993

Kessler, R M, Whetsell, W O, Ansari, M S, Votaw, J R, de Paulis, T, Clanton, J A, Schmidt, D E, Mason, N S, Manning, R G. Identification of extrastriatal dopamine D2 receptors in post mortem human brain with [125I]epidepride. Brain Res, 609(1-2), 237-43, 1993

Votaw, J R, Kessler, R M, de Paulis, T. Failure of the three compartment model to describe the pharmacokinetics in brain of a high affinity substituted benzamide. Synapse, 15(3), 177-90, 1993

Hoff, S J, Stewart, J R, Frist, W H, Kessler, R M, Sandler, M P, Atkinson, J B, Votaw, J, Carey, J A, Ansari, M S, Merrill, W H. Noninvasive detection of heart transplant rejection with positron emission scintigraphy. Ann Thorac Surg, 53(4), 572-7, 1992

Kessler, R M, Mason, N S, Votaw, J R, De Paulis, T, Clanton, J A, Ansari, M S, Schmidt, D E, Manning, R G, Bell, R L. Visualization of extrastriatal dopamine D2 receptors in the human brain. Eur J Pharmacol, 223(1), 105-7, 1992

Maciunas, R J, Kessler, R M, Maurer, C, Mandava, V, Watt, G, Smith, G. Positron emission tomography imaging-directed stereotactic neurosurgery. Stereotact Funct Neurosurg, 58(1-4), 134-40, 1992

Kessler, R M, Ansari, M S, Schmidt, D E, de Paulis, T, Clanton, J A, Innis, R, al-Tikriti, M, Manning, R G, Gillespie, D. High affinity dopamine D2 receptor radioligands. 2. [125I]epidepride, a potent and specific radioligand for the characterization of striatal and extrastriatal dopamine D2 receptors. Life Sci, 49(8), 617-28, 1991

Kessler, R M, Ansari, M S, de Paulis, T, Schmidt, D E, Clanton, J A, Smith, H E, Manning, R G, Gillespie, D, Ebert, M H. High affinity dopamine D2 receptor radioligands. 1. Regional rat brain distribution of iodinated benzamides. J Nucl Med, 32(8), 1593-600, 1991

Conturo, T E, Kessler, R M, Beth, A H. Cooperative T1 and T2 effects on contrast using a new driven inversion spin-echo (DISE) MRI pulse sequence. Magn Reson Med, 15(3), 397-419, 1990

Creasy, J L, Price, R R, Presbrey, T, Goins, D, Partain, C L, Kessler, R M. Gadolinium-enhanced MR angiography. Radiology, 175(1), 280-3, 1990

Janowsky, A, De Paulis, T, Clanton, J A, Smith, H E, Ebert, M H, Kessler, R M. [125I]iodopride: a specific high affinity radioligand for labelling striatal dopamine D-2 receptors. Eur J Pharmacol, 150(1-2), 203-5, 1988

Powers, T A, Partain, C L, Kessler, R M, Freeman, M W, Robertson, R H, Wyatt, S H, Whelan, H T. Central nervous system lesions in pediatric patients: Gd-DTPA-enhanced MR imaging. Radiology, 169(3), 723-6, 1988

de Paulis, T, Janowsky, A, Kessler, R M, Clanton, J A, Smith, H E. (S)-N-[(1-ethyl-2-pyrrolidinyl)methyl]-5-[125I]iodo- 2-methoxybenzamide hydrochloride, a new selective radioligand for dopamine D-2 receptors. J Med Chem, 31(10), 2027-33, 1988

Freeman, M P, Kessler, R M, Allen, J H, Price, A C. Craniopharyngioma: CT and MR imaging in nine cases. J Comput Assist Tomogr, 11(5), 810-4, 1987

Postdoctoral Position Available
N/A

Postdoctoral Position Details
N/A

Updated Date
07/29/2005

Vanderbilt University is committed to principles of equal opportunity and affirmative action.
For More Information: Jeremy J. Kaye, M.D.
Copyright © 2002, Educational Technology, Biomedical Research Education & Training
Last Modified: June 29, 2007
webmaster@www.mc.Vanderbilt.Edu