The Vanderbilt Department of Anesthesiology welcomes Pei Tang, PhD, Professor of Anesthesiology, Pharmacology & Chemical Biology, and Computational & Systems Biology at the University of Pittsburgh School of Medicine for a special guest lecture. Dr. Tang's talk, "Atomic View of Anesthetic Action" is Thursday, September 5, at 3:30 p.m. at 512 Light Hall.
Dr. Tang is one of the world's leading experts on the molecular mechanisms of general anesthesia, a century-long medical practice that remains undefined functionally at the molecular and cellular level. Her investigations have focused on the molecular nature of general anesthetic interaction with pentameric ligand gated ion channels (pLGICs). She has combined the use of various biophysical approaches, notably the state-of-the-art high-resolution nuclear magnetic resonance (NMR) spectroscopy, X-ray crystallography, and molecular dynamics simulations, to elucidate general anesthetic effects on the structures and dynamics of pLGICs.