Eicosanoid Core Laboratory
The Eicosanoid Core Laboratory is a Vanderbilt University Shared Resource designated for the analysis of isoprostanes, prostaglandins, leukotrienes, and their metabolites. The services available in the Core are listed in the Table below. All of the assays performed are validated highly precise, accurate, and sensitive mass spectrometric assays, many of which were developed by Core personnel.
| Analyte | Matrix |
| F2-Isoprostanes | Plasma, Urine, Tissues, CSF, EBC, BAL |
| F2-Isoprostane metabolite | Urine |
| F3-Isoprostanes (from eicosapentaenoic acid) | Tissues, Urine |
| Neuroprostanes (F4-IsoPs, from docosahexaenoic acid) | Tissues, CSF,Urine |
| Isofuranes | Plasma, Urine, Tissues, EBC, BAL |
| Thromboxane B2 | Serum |
| PGE2 metabolite | Urine |
| PGD2 metabolite | Urine |
| Prostacyclin metabolite | Urine |
| Thromboxane metabolite | Urine |
| Leukotriene E4 | Urine |
| Parent Prostaglandins (F, D, E, J, A, prostacyclin, thromboxane) | Tissues, EBC, BAL, Cells |
