Iverson Lab


McCulloch, K.M., McCranie, E.K., Smith, J.A., Sarwar, M., Mathieu, J.L., Gitschlag, B.L., Du, Y., Bachmann, B.O., and Iverson, T.M. (2015) Oxidative cyclizations in orthosomycin biosynthesis expand the known chemistry of an oxygenase superfamily. Proc Natl Acad Sci USA. PMID: 26240321

Chen, Q., Vishnivetskiy, S.A., Zhuang, T., Cho, M.K., Thaker, T.M., Sanders, C.R., Gurevich, V.V., and Iverson, T.M. (2015) The rhodopsin-arrestin-1 interaction in bicelles. Methods Mol. Biol. 1271:77-95

Kaya, A.I., Iverson T.M., and Hamm, H.E. (2015) Functional stability of rhodopsin in a bicelle system: evaluating G protein activation by rhodopsin in bicelles. Methods Mol. Biol. 1271:67-76

Vishnivetskiy, S.A., Zhan, X., Chen, Q., Iverson, T.M., and Gurevich, V.V. (2014) Arrestin expression in E. coli and purification.  Curr. Protoc. Pharmacol. 67(Unit 2.11)

Kaya, A.I., Lokits, A.D., Gilbert, J.A., Iverson, T.M., Meiler, J., and Hamm, H.E. (2014) A conserved phenylalanine as a relay between the α5 helix and the GDP binding region of heterotrimeric Gi protein α subunit.  J. Biol. Chem. 289(35):24475-24487

Thaker, T.M., Preininger, A.M., Sarwar, M., Hamm, H.E., and Iverson T.M. (2014) A transient interaction between the P-loop and Switch I contributes to the allosteric network between receptor and nucleotide in Gai1. J. Biol. Chem. 289(16):11331-11341

Birmingham, W.R., Nannemann, D.P., Starbird, C.A., Panosian, T.D., Iverson T.M., and Bachmann, B.O. (2014) Bioretrosynthetic construction of a didanosine biosynthetic pathway. Nat. Chem. Biol. 10(5):392-399

Seo, H.S., Misanov, G., Seepersaud, R., Doran, K.S., Dubrovska, I., Shuvalova, L., Anderson, W.F., Iverson T.M., and Sullam, P.M. (2013) Characterization of Fibrinogen Binding by Glycoproteins Srr1 and Srr2 of Streptococcus agalactiae. J. Biol. Chem. 288(50): 35982–35996

Singh P.K., Sarwar M., Maklashina E., Kotlyar V., Rajaqukquk S., Tomasiak T.M., Cecchini G., Iverson T.M. (2013) Plasticity of the Quinone-Binding Site of the Complex II Homolog Quinol:Fumarate Reductase. J. Biol Chem. PMID: 23836905

Zhuang T., Chen Q., Cho M.K., Vishnivetskiy S.A., Iverson T.M., Gurevich V.V., and Sanders C.R. (2013) Involvement of distinct arrestin-1 elements in binding to different functional forms of rhodopsin. Proc Natl Acad Sci USA 110(3): 942-947

Vishnivetskiy S.A., Chen Q., Palazzo M.C., Brooks E.K., Altenbach C., Iverson T.M., Hubbell W.L., and Gurevich V.V. (2013) Engineering visual arrestin-1 with special functional characteristics. J Biol Chem 288(5): 3394-405.

Thaker T.M., Tanabe M., Fowler M.L., Preininger A.M., Ingram-Smith C., Smith K.S., and Iverson T.M. (2013) Crystal structures of acetate kinases from the eukaryotic pathogens Entamoeba histolytica and Cryptococcus neoformans. J Struct Biol. 181(2):185-9.

Iverson T.M. (2012) Catalytic mechanisms of complex II enzymes: A structural perspective. Biochim Biophys Acta. Sep 18. pii: S0005-2728(12) 01031-6. PMID: 22995215, PMCID:PMC3537904 [Available on 2014/3/18]

Iverson T.M., Maklashina E., and Cecchini G. (2012) Structural basis for malfunction in complex II. J Biol Chem. 287(42): 35430-8. PMID:22904323, PMCID:PMC3471735 [Available on 2013/10/12]

Iverson T.M., Panosian, T.D., Birmingham, W., Nannemann, D. P., and Bachmann, B.O. (2012) Molecular differences between a mutase and a phosphatase: investigations of the activation step in Bacillus cereus phosphopentomutase. Biochemistry. 51(9): 1964-1975. PMID: 22329805, PMCID:PMC3302354 [Available on 2013/3/6]

Thaker, T.M., Kaya, A.I., Preininger, A.M., Hamm, H.E., and Iverson, T.M., (2011) Allosteric Mechanisms of G protein Coupled Receptor Signaling: A Structural Perspective, in A. Fenton (ed.) Methods in Molecular Biology - Allostery: Methods and Protocols, Humana Press, New York, NY. (2011) Part II, Chapter 8, pp. 133-174.

Pyburn, T.M., Bensing, B.A., Melancon, B.J., Tomasiak, T.M., Yankovskaya, V., Oliver, K., Ward, N.J., Sulikowski, G.A., Cecchini, G., Tyska, M.J., Sullam, P.M., and Iverson, T.M. (2011) A structural model for binding of the serine-rich repeat adhesin GspB to host carbohydrate receptors. PLoS Pathogens. 7(7): e1002112. PMCID:PMC3131266

Kaya, A.I., Thaker, T.M., Preininger, A.M., Iverson, T.M., and Hamm, H.E. (2011) Coupling efficiency of rhodopsin and transducin in bicelles. Biochemistry. 50(15): 3193-3203. PMCID:PMC3119548

Kuchtey, J., Olson, L.M., Rinkoski, T., MacKay, E.O., Iverson, T.M. Gelatt, K.N., Haines, J.L. and Kuchtey, R.W. (2011) Mutation in ADAMTS10 in a canine model of primary open angle glaucoma. PLoS Genetics. 7(2): e1001306. PMCID:PMC3040645

Panosian, T.D., Nannemann, D.P., Watkins, G., Wadzinski, B., Bachmann, B.O., and Iverson, T.M. (2011) Bacillus cereus phosphopentomutase is an alkaline phosphatase family member that exhibits an altered catalytic cycle. J. Biol Chem. 286(10): 8043-8054. PMCID:PMC3048691

Tomasiak, T.M., Archuleta, T.L., Andréll, J., Luna-Chavez, C., Davis, T., Sarwar, M., Ham, A.J., McDonald, H., Yankovskaya, V., Maklashina, E., Stern, H.A., Johnston, J.N., Cecchini, G., and Iverson, T.M. (2011) Geometric restraints drive on- and off-pathway catalysis in the Escherichia coli menaquinol:fumarate reductase. J. Biol. Chem. 286(4): 3047-3056. PMCID:PMC3024798

Pyburn T., Bensing B., Yankovskaya V., Sullam P.M., Iverson T.M. (2010) Purification, crystallization, and preliminary x-ray diffraction analysis of the carbohydrate binding region of the Streptococcus gordonii adhesin GspB. Acta crystallogr. F66(11): 1503-1507. PMCID:PMC3001660

Vey J.L., Al-Mestarihi A., Funk M.A., Bachmann B.O., Iverson T.M. (2010) Structure and mechanism of ORF36, an amino sugar oxidizing enzyme in everninomicin biosynthesis. Biochemistry. 49(43): 9306-9317. PMCID:PMC2964426

Panosian T.D., Nannemann D.P., Bachmann B.O., Iverson T.M. (2010) Crystallization and preliminary X-ray analysis of a phosphopentomutase from Bacillus cereus. Acta Crystallogr. F66(7): 811-814. PMCID:PMC2898468

Tanabe M., Nimigean C.M., Iverson, T.M. (2010) Structural basis for solute transport, nucleotide regulation, and immunological recognition of Neisseria meningitidis PorB. Proc. Natl. Acad. Sci. USA. 107(15): 6811-6816. PMCID:PMC2872391

Thompson A.N., Kim I., Panosian T.D., Iverson T.M., Allen W.A., Nimigean C.M. (2009) Mechanism of potassium-channel selectivity revealed by Na+ and Li+ binding sites within the KcsA pore. Nat. Struct. & Molec Biol. 16(12): 1317-U1143. PMCID:PMC2825899

Tanabe M., Iverson T.M. (2009) Expression, purification and preliminary X-ray analysis of the Neisseria meningitidis outer membrane protein PorB. Acta Crystallogr. F65(10): 996-1000. PMCID:PMC2765884

Adler D.H., Phillips J.A., Cogan J.D., Iverson T.M., Stein J.A., et al. (2009) The enteropathy of prostaglandin deficiency. J. Gastroenterol. 44(Suppl 19): 1-7. PMCID:PMC2799331

Preininger A.M., Funk M.A., Oldham W.M., Meier S.M., Johnston C.A., Adhikary S., et al. (2009) Helix dipole movement and conformational variability contribute to allosteric GDP release in Gαi subunits. Biochemistry. 48(12): 2630-2642. PMCID:PMC2736342

Tanabe M., Iverson T.M. (2009) A Practical Guide to X-Ray Crystallography of beta-barrel Membrane Proteins: Expression, Purification, Detergent Selection, and Crystallization. Membrane Protein Crystallization: 63, 229-267.

Tomasiak T.M., Maklashina E., Cecchin, G., Iverson, T.M. (2008) A threonine on the active site loop controls transition state formation in Escherichia coli respiratory complex II. J. Biol Chem. 283(22): 15460-15468. PMCID:PMC2397489

Cecchini G., Maklashina E., Tomasiak T.M., Iverson T.M. Conformational Changes at the Dicarboxylate Binding Site of Succinate Dehydrogenase (Complex II) and Fumarate Reductase, in Frago S., Gómez-Moeno C, Medina M. (eds.) Flavins and Flavoproteins, Prensas Universitarias de Zaragoza (2008) pp. 17-26.

Adler D.H., Cogan J.D., Phillips J.A., Schnetz-Boutaud N., Milne G.L, Iverson T.M., Stein J.A., Brenner D.A., Morrow J.D., Boutaud O., Oates J.A. (2008) Inherited human cPLA2α deficiency is associated with impaired eicosanoid biosynthesis, small intestinal ulceration, and platelet dysfunction. J. Clin. Invest. 118:2121-2131. PMCID:PMC2735913

Tomasiak T.M., Cecchini G., Iverson T.M. Succinate as Donor; Fumarate as Acceptor, in A. Böck, R. Curtiss III, J. B. Kaper, F. C. Neidhardt, T. Nyström, J. M. Slauch, and C. L. Squires (ed.), EcoSal — Escherichia coli and Salmonella: Cellular and Molecular Biology. www.ecosal.org. ASM Press, Washington, D.C. (2007) 13 August 2007, posting date, Chapter 3.2.6.

Iverson T.M. (2006) Evolution and unique bioenergetic mechanisms in oxygenic photosynthesis. Curr Opin Chem Biol. 10(2): 91-100. PMID: 16504567 [PubMed - indexed for MEDLINE]

Maklashina E., Iverson T.M., Sher Y., Kotlyar V., Andréll J., Mirza O., Hudson J.M., Armstrong F.A., Rothery R.A., Weiner J.H., Cecchini G. (2006) Fumarate reductase and succinate oxidase activity of Escherichia coli complex II homologs are perturbed differently by mutation of the flavin binding domain. J. Biol. Chem. 281(16): 11357-11365. PMID: 16484232 [PubMed - indexed for MEDLINE]

Ferreira K.N., Iverson T.M., Maghaloui K., Iwata S, and Barber J. (2004) Architecture of the oxygen evolving centre of photosystem II. Science, 303(5665): 1831-1838 co-first author. PMID: 14764885 [PubMed - indexed for MEDLINE]

Cecchini G., Maklashina E., Yankovskaya V., Iverson T.M., Iwata S. (2003) Variation in proton donor/acceptor pathways in succinate:quinone oxidoreductases. FEBS Lett. 545(1), 31-8. PMID: 12788489 [PubMed - indexed for MEDLINE]

Doukov T.I., Iverson T.M., Seravalli J., Ragsdale S.W., Drennan C.L. (2002) A Ni-Fe-Cu center in a bifunctional carbon monoxide dehydrogenase/acetyl-CoA synthase. Science, 298(5593), 567-72. PMID: 12386327 [PubMed - indexed for MEDLINE]

Iverson T.M., Luna-Chavez C., Croal L.R., Cecchini G., Rees D.C. (2002) Crystallographic studies of the Escherichia coli quinol-fumarate reductase with inhibitors bound to the quinol-binding site. J Biol Chem, 277(18), 16124-30. PMID: 11850430 [PubMed - indexed for MEDLINE]

Iyer R., Iverson T.M., Accardi A., Miller C. (2002) A biological role for prokaryotic ClC chloride channels. Nature, 419(6908), 715-8.

Iverson T.M., Arciero D.M., Hooper A.B., Rees D.C. (2001) High-resolution structures of the oxidized and reduced states of cytochrome c554 from Nitrosomonas europaea. J Biol Inorg Chem, 6(4), 390-7. PMID: 11372197 [PubMed - indexed for MEDLINE]

Strop P., Smith K.S., Iverson T.M., Ferry J.G., Rees D.C. (2001) Crystal structure of the 'cab'-type beta class carbonic anhydrase from the archaeon Methanobacterium thermoautotrophicum. J Biol Chem, 276(13), 10299-305. PMID: 11096105 [PubMed - indexed for MEDLINE]

Iverson, T.M., Luna-Chavez, C, Schröder, I, Cecchini, G, Rees, D C. (2000) Analyzing your complexes: structure of the quinol-fumarate reductase respiratory complex. Curr Opin Struct Biol, 10(4), 448-55. PMID: 10981634 [PubMed - indexed for MEDLINE]

Iverson T.M., Alber B.E., Kisker C., Ferry J.G., Rees D.C. (2000) A closer look at the active site of gamma-class carbonic anhydrases: high-resolution crystallographic studies of the carbonic anhydrase from Methanosarcina thermophila. Biochemistry, 39(31), 9222-31. PMID: 10924115 [PubMed - indexed for MEDLINE]

Luna-Chavez C., Iverson T. M., Rees D.C., Cecchini G. (2000) Overexpression, purification, and crystallization of the membrane-bound fumarate reductase from Escherichia coli. Protein Expr Purif, 19(1), 188-96. PMID: 10833406 [PubMed - indexed for MEDLINE]

Iverson T.M., Luna-Chavez C., Cecchini G., Rees D.C. (1999) Structure of the Escherichia coli fumarate reductase respiratory complex. Science, 284(5422), 1961-6. PMID: 10373108 [PubMed - indexed for MEDLINE]

Iverson T.M., Arciero D.M., Hsu B.T., Logan M.S., Hooper A.B., Rees D C. (1998) Heme packing motifs revealed by the crystal structure of the tetra-heme cytochrome c554 from Nitrosomonas europaea. Nat Struct Biol, 5(11), 1005-12. PMID: 9808046 [PubMed - indexed for MEDLINE]


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