The objective of the Cardiovascular Pathophysiology and Complications Core (CPCC) is to provide investigators at Vanderbilt and outside institutions a cost-effective means to accurately assess cardiovascular phenotypes in mouse models of diabetes and metabolic disease. The CPCC uses validated approaches and state-of-the-art instrumentation that allow for sensitive screening of phenotypic variations. For many studies, multiple measurements can be coordinated with the other Cores of the MMPC: for example, non-invasive serial echocardiographic and blood pressure determinations during a period of high-fat feeding or other environmental stress, measuring the metabolic response to exercise on a subset of mice, and histologic evaluation on sacrifice. The CPCC also offers several surgical techniques to induce myocardial injury (infarction, aortic banding, and ischemia/reperfusion injury).
Chee Lim, Ph.D., Director
2220 Pierce Avenue, PRB 332
Vanderbilt University Medical Center
Nashville, TN 37232
Preston Research Building, Room 336
Chee Chew Lim, Ph.D.
Jeffrey Rottman, M.D.
Michael F. Hill, Ph.D.
Lianli Ma, M.D.
Lin Zhong, Ph.D.
Description of Services
Cost for Investigator-initiated research
Cost for Industry-initiated research