The objective of the Cardiovascular Pathophysiology and Complications Core (CPCC) is to provide investigators at Vanderbilt and outside institutions a cost-effective means to accurately assess cardiovascular phenotypes in mouse models of diabetes and metabolic disease. The CPCC uses validated approaches and state-of-the-art instrumentation that allow for sensitive screening of phenotypic variations. For many studies, multiple measurements can be coordinated with the other Cores of the MMPC: for example, non-invasive serial echocardiographic and blood pressure determinations during a period of high-fat feeding or other environmental stress, measuring the metabolic response to exercise on a subset of mice, and histologic evaluation on sacrifice. The CPCC also offers several surgical techniques to induce myocardial injury (infarction, aortic banding, and ischemia/reperfusion injury).
Contact information:
Chee Lim, Ph.D., Director
2220 Pierce Avenue, PRB 332
Vanderbilt University Medical Center
Nashville, TN 37232
Office: 615-936-2510
Preston Research Building, Room 336
Co-Directors:
Chee Chew Lim, Ph.D.

Jeffrey Rottman, M.D.
Associate Director:
MacRae Linton
Staff:
Michael F. Hill, Ph.D.
ZhiZhang Wang
Lianli Ma, M.D.
Lin Zhong, Ph.D.
Description of Services
Cost for Investigator-initiated research
Cost for Industry-initiated research