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Mouse Metabolic Phenotyping Center

Cost for Services - Investigator-initiated research

Metabolic Pathophysiology Core

Charges reflect those for investigator-initiated research.

Surgical (Only charged for successful surgeries (animal healthy, catheters functioning). 

 

Costs (per mouse) for Vandy Clamp Procedures (includes surgery)
Hyperinsulinemic euglycemic clamp with [3-3H] glucose
This procedure will allow investigators to assess whole body insulin action and the ability of insulin to suppress endogenous (i.e. hepatic) glucose production.
$317
Hyperinsulinemic euglycemic clamp with [2-3H] deoxyglucose
This procedure will allow investigators to assess whole body insulin action and the rates of glucose uptake by multiple (e.g.  brain, heart, muscle and fat).
$400
Hyperinsulinemic euglycemic clamp with [3-3H] glucose and [14C] deoxyglucose
This procedure will allow investigators to assess whole body insulin action, the ability of insulin to suppress endogenous (i.e. hepatic) glucose production and the rates of glucose uptake by multiple tissues (e.g. brain, heart, muscle and fat).
$416
Hyperglycemic clamp
This procedure will allow investigators to assess the ability of the pancreas to respond to an acute increase in glucose levels by monitoring the time course of insulin and c-peptide concentration.
$394
*** Note: typically to compare groups, 6-8 animals/group is needed. Prices do not include cost for shipping or quarantine.
Costs for Individual Surgical Services
Chronic Arterial and Jugular Vein Catheterization
$100
Chronic Arterial or Jugular Vein Catheterization
$60
Bariatric Surgery (Roux-en-Y gastric bypass, sleeve gastrectomy, Biliopancreatic diversion)
$110
Portal Vein Catheterization
$90
Surgical Implantation of Mini-Mitter® Telemetry Transmitter
$30
Intracerebroventricular Cannulation (Lateral Ventricle; For Other Ventricles or Specific Nuclei Cannula Placement Contact Director)
$80
Acute Arterial and Jugular Vein Catheterization
$85
Acute Arterial or Jugular Vein Catheterization
$50
Bladder Catheterization
$11
*Other surgeries can be arranged with Director
** Charges are per successful completed procedure
Costs for Individual Nonsurgical Services
Basal Arterial Samples
$14
Treadmill Exercise Study (VO2 max, endurance)
$45
Body Temperature (Subcutaneous)
$15
Sacrifice and Excise Tissue
$10
Perfusion and Fixation
$16
Urine Collection (1 mouse per metabolic cage)
$2
Vein Blood Collection/Injection
$3
Manual Measurement of Food Intake                         
$3.25
Body Composition Analysis by NMR
$10
Monitoring of Body Weight/composition Changes in Response to Long Term Diet Manipulation (cost/week + cost of diet)
$15
Indirect Calorimetry using the Columbus Instruments Oxymax® System. Body Composition Analysis Included (84h of measurement; 8 mouse minimum)
$55
Comprehensive Assessment of Energy Balance Using Promethion® System (indirect calorimetry, home cage activity, food intake, fluid intake, meal-patterning, wheel running). Body Composition Analysis Included. (84h of measurement; 8 mouse minimum)
$60
Wheel-running Behavior Using Mini-Mitter® System. Body Composition Analysis Included. (84h of measurement; 8 mouse minimum)
$60
Measurement of Core Body Temperature/Home Cage Activity by Remote Radiotelemetry(84h of measurement; 8 mouse minimum)
$60
Basic Data Analysis for Promethion®, Mini-Mitter® and Telemetry Experiments *cost per experiment (not per mouse)
$200
Intracerevbroventricular (i.c.v.) Administration of Exogenous Compounds (including habituation)
$30
Intraperitoneal (i.p.) Administration of Exogenous Compounds (including habituation)
$15
Conditioned Taste Aversion, Pica assay, Diet Preference:  Arrange with Director
Telemetry (see Cardiovascular Pathophysiology and Complications Core)
Imaging (e.g. confocal, Luminescence)  see director
Other Procedures can be arranged with director
Costs for Analytical Services
Blood panel A (fresh whole blood only): Na, K, Cl, pH, pCO2, HCO3, base excess, anion gap, BUN, hemoglobin, hematocrit
$23.50
Blood panel B (fresh whole blood only): K, iCa, pH, pCO2, pO2, sO2, TCO2, HCO3, glucose, hemoglobin, hematocrit
$17.50
Blood Glucose
$7
Blood Glycosylated Hb
$14
Blood Creatinine
$12
Urine Albumin/Creatinine
$13
Resource Usage
Instructional Resources – Research assistant time ($13.00 per hour) plus supply costs
Research and Development: Arrange with Director
Murine Pancreatic Islet Isolation Core Services: Arrange with Director

 

Add 20% administrative fee to cost for investigators outside Vanderbilt.

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