.

Testing for Hematologic Malignancy

Click here for specimen test instructions.

Select how you would like to view the tests, then click on the name of the test for a detailed summary.

Karyotype

AML FISH panel

MDS FISH panel

ALL FISH panel

FISH with 9q34 (ABL1)/22q11.2 (BCR) for detection of t(9;22)(q34;q11.2) in chronic myelogenous leukemia (CML)

CLL FISH panel

FISH testing for non-Hodgkin lymphoma

Myeloma FISH panel

FISH for myeloproliferative neoplasms with eosinophilia

X/Y FISH

B-cell receptor (immunoglobulin heavy chain) gene rearrangement by PCR

T-cell receptor gamma gene rearrangement by PCR

BCL2 rearrangements by PCR

FLT3 internal tandem duplication (ITD) by PCR

NPM1 mutation by PCR

JAK2 V617F mutation by PCR

BCR/ABL1 (p210/p190) rearrangements by PCR

KIT D816V mutation by PCR

 
This assay is performed at Mayo Medical Laboratories by a qualitative, allele-specific PCR assay.

CEBPA mutations by DNA sequencing

PML/RARA rearrangement by PCR

Bone marrow engraftment by PCR

Acute Myeloid Leukemia (AML)

Karyotype
AML FISH panel
MDS FISH panel
X/Y FISH
FLT3 internal tandem duplication (ITD) by PCR
NPM1 mutation by PCR
KIT D816V mutation by PCR
CEBPA mutations by DNA sequencing
PML/RARA rearrangement by PCR
Bone marrow engraftment by PCR

Myelodysplastic Syndrome (MDS) or Bone Marrow Failure

Karyotype
MDS FISH panel
X/Y FISH
Bone marrow engraftment by PCR

Acute Lymphoblastic Leukemia

Karyotype
ALL FISH panel
X/Y FISH
BCR/ABL1 (p210/p190) rearrangements by PCR
T-cell receptor gamma gene rearrangement by PCR
Bone marrow engraftment by PCR

Plasma Cell Myeloma

Karyotype
Myeloma FISH panel
X/Y FISH
Bone marrow engraftment by PCR  

Myeloproliferative Neoplasms (MPN)

Karyotype
FISH with 9q34 (ABL1)/22q11.2 (BCR) for detection of t(9;22)(q34;q11.2)
FISH for myeloproliferative neoplasms with eosinophilia
X/Y FISH
JAK2 V617F mutation by PCR
BCR/ABL1 (p210/p190) rearrangements by PCR
Bone marrow engraftment by PCR

Lymphoma

Karyotype
CLL FISH panel
FISH testing for non-Hodgkin lymphoma
X/Y FISH
B-cell receptor (immunoglobulin heavy chain) gene rearrangement by PCR
T-cell receptor gamma gene rearrangement by PCR
BCL2 rearrangements by PCR
Bone marrow engraftment by PCR
 

Additional esoteric testing services are also offered. Diagnostic Mentor provides state-of-the-art molecular profiling on a variety of specimens. Our experts are always available to provide consultation and advice.

Esoteric Testing

Current testing available:
  • Molecular Profiling of Melanoma
  • Molecular Profiling of Lung Cancer
  • Molecular Profiling of Colon Cancer
  • Molecular Profiling of Breast Cancer
For more information about esoteric testing, explore:
  • Test Methodology
  • Sample Requirements
  • Result Reporting

Tests may be ordered through Vanderbilt Pathology Laboratory Services (VPLS). Contact VPLS for specific panel CPT codes and prices.

VPLS provides you with all the necessary collection and transport supplies, reporting, billing and customer support services to facilitate your specimen referrals.




This diagnostic process was designed by physicians for physicians. Every step of the process is managed by highly trained experts.

This page was last updated July 30, 2013 and is maintained by