.

Vanderbilt Department of Neurology

Faculty By Divisions


Kevin Haas, M.D., Ph.D.

BIOGRAPHICAL SKETCH

Dr. Haas earned his B.S. in biomedical engineering from Duke University in 1991, graduating magna cum laude with distinction. His graduate and medical school training took place at the University of Michigan, where he earned his Ph.D. degree in neuroscience in 1998 and M.D. degree in 1999. At Emory University, he completed his internal medicine internship in 2000, neurology residency at in 2003, and clinical neurophysiology fellowship with an emphasis in epilepsy in 2004. He served as chief resident in neurology for the 2002-2003 medical year.

In 2004, Dr. Haas joined the Vanderbilt University Medical Center faculty as an assistant professor in the neurology department and is board certified in both Neurology and Clinical Neurophysiology.  His clinical focus is epilepsy and he is an attending physician for general neurology and the epilepsy monitoring unit.  He is the neurology director for epilepsy surgery. Dr. Haas is a fellow of the American Neurological Association, and a member of the American Academy of Neurology and the American Epilepsy Society.


RESEARCH SUMMARY

My basic research experience has focused on GABA-A receptor physiology, synaptic roles of ubiquitination, and epilepsy in Angelman syndrome. I am an author/co-author on numerous original articles in these fields and serve on the scientific advisory committee for the Foundation for Angelman Syndrome Therapeutics. I have recently developed clinical epilepsy research projects focused on epilepsy surgery, status epilepticus, treatment of neurogenetic epilepsy syndromes, and epilepsy pharmacogenomics.

I am the Vanderbilt site principal investigator for the Critical Care EEG Consortium and actively involved in projects investigating the diagnosis and treatment of status epilepticus.

I have conducted clinical trials of experimental and new antiepileptic drugs and those currently being investigated include brivaracetam for partial and generalized epilepsy and intranasal diazepam for acute repetitive seizures.

 

RECENT PUBLICATIONS

Vendrame M, Loddenkemper T, Zarowski M, Gregas M, Shuhaiber H, Sarco DP, Morales A, Nespeca M, Sharpe C, Haas K, Barnes G, Glaze D, Kothare SV, (2012) Analysis of EEG patterns and genotypes in patients with Angelman syndrome.  Epilepsy and Behavior, 23(3):261-5.

Gustin RM, Bichell TJ, Bubser M, Daily J, Filanova I, Mreshavili D, Deutch AY, Colbran RJ, Weeber   EJ, Haas KF, (2010) Tissue-specific variation of Ube3a protein expression in rodents and in a mouse             model of Angelman syndrome.  Neurobiology of Disease 39(3): 283-291.

Mengesha T, Abu-Ata M, Haas KF, Lavin PJ, Sun DA, Konrad PE, Pearson M, Wang L, Song Y, Abou-Khalil BW (2009). Visual field defects after selective amygdalohippocampectomy and standard temporal lobectomy. Journal of Neuro-Ophthalmology, 29(3) 208-213.

Haas, KF, Broadie, K (2008) Roles of ubiquitination at the synapse, BBA Gene Regulatory Mechanisms, 1779(8) 495-506.

Bianchi, MT, Botzolakis, Haas, KF, Fisher, JL, and Macdonald, RL (2007) Microscopic kinetic determinants of macroscopic currents: insights from coupling and uncoupling of GABAA receptor desensitization and deactivation. Journal of Physiology 584(3) 769-787.

Haas KF, Wooodruff III, Elvin, and Broadie, K (2007) Proteasome Function is Required to Maintain Muscle Cellular Architecture. Biology of the Cell 99(11) 615-626.

Haas, KF, Miller, SL, Friedman, DB, Broadie, K. The ubiquitin-proteasome system postsynaptically regulates glutamatergic synaptic function. Mol Cell Neurosci, 35(1), 64-75, 2007


Contact Information
Kevin F. Haas M.D., Ph.D.
Assistant Professor of Neurology
Epilepsy Division
Neurology Directory of Epilepsy Surgery
1161 21st Ave South
A-0118 MCN
Nashville, TN 37232
Phone: 615-936-0060
Fax: 615-936-0223

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