Richard C. Shelton, M.D.
James G. Blakemore Research Professor of Psychiatry and Professor of Pharmacology
Vice Chair for Clinical Research
richard.shelton@vanderbilt.edu
Dr. Shelton has been on the faculty of the Department since 1985. His research interest is in mood disorders, and he established the Mood Disorders Research Program at Vanderbilt. Active research studies range from the basic neuronal basis of mood disorders, through treatment research (including both psychotherapy and medication), to primary prevention studies.
Education
M.D., University of Louisville, KY
B.S., East Tennessee State University
Postgraduate Training
Resident in Psychiatry, the Massachusetts Mental Health Center (now Longwood Program), Harvard Medical School, Boston, MA.
Research Fellow, National Institute of Mental Health, Washington, D.C.
Areas of Clinical Expertise
Mood and anxiety disorders
Research interests
Mood disorders (basic, translational, and clinical)
Representative publications
1. Keller N.R., Diedrich A., Appalsamy M., Miller L.C., McDonald M., Shelton R.C., Blakely R.D., Robertson D. Norepinephrine transporter- (NET-) deficient mice respond to stress-inducing and fearful environments with bradycardia and hypotension. Neuroscience 139:931-946, 2006.
2. Mazei-Robison M.S., Couch R.S., Shelton R.C., Blakely R.D. Sequence variation in the human dopamine transporter gene in children with attention deficit hyperactivity disorder. Neuropharmacology 49:724-736, 2005.
3. Prasad HC Zhu ZB McCauley JL Shelton R Hewlett WA Sutcliffe JS Blakely RD. Human serotonin transporter variants display selective insensitivity to protein kinase G and p38 mitogen activated protein kinase. Proceedings of the National Academy of Sciences USA 102:11545-11550, 2005.
4. Shelton RC Williamson D Corya SA Sanger TM Van Campen LE Case M Briggs SD Tollefson GD. Olanzapine/Fluoxetine combination for treatment resistant depression: A controlled study of SSRI and nortriptyline resistance. J Clin Psychiatry 66:1289-1297, 2005.
5. Hollon S.D., DeRubeis R.J., Shelton R.C., Amsterdam J.D., Salomon R.M., O’Reardon J.P., Lovett M.L., Young P.R., Haman K.L., Freeman B.A., Gallop R. Prevention of relapse following cognitive therapy versus medications in moderate to severe depression. Arch Gen Psychiatry 62:417-422 2005.
