Parl FF, Dawling S, Roodi N, Crooke PS. Estrogen metabolism and breast cancer. A risk model. AA NY Acad Sci, 1155, 68-75, 2009
Parl FF, Egan KM, Li C, Crooke PS. Estrogen exposure, metabolism, and enzyme variants in a model for breast cancer risk prediction. Cancer Informatics, 7, 109-121, 2009
Parl FF. A need for true GSTM1 and GSTT1 genotyping. Cancer Epidemiol Biomarkers Prev, 18, 2793, 2009
Belous, AR, Hachey, DL, Dawling, S, Roodi, N, Parl, FF. Cytochrome P450 1B1-mediated estrogen metabolism results in estrogen-deoxyribonucleoside adduct formation. Cancer Res, 67(2), 812-7, 2007
Bradley, C, van der Meer, R, Roodi, N, Yan, H, Chandrasekharan, MB, Sun, ZW, Mernaugh, RL, Parl, FF. Carcinogen-induced histone alteration in normal human mammary epithelial cells. Carcinogenesis, 28(10), 2184-92, 2007
Crooke, PS, Ritchie, MD, Hachey, DL, Dawling, S, Roodi, N, Parl, FF. Estrogens, enzyme variants, and breast cancer: a risk model. Cancer Epidemiol Biomarkers Prev, 15(9), 1620-9, 2006
McLaren, BK, Gobbi, H, Schuyler, PA, Olson, SJ, Parl, FF, Dupont, WD, Page, DL. Immunohistochemical expression of estrogen receptor in enlarged lobular units
with columnar alteration in benign breast biopsies: a nested case-control study. Am J Surg Pathol, 29(1), 105-8, 2005
Canter, JA, Kallianpur, AR, Parl, FF, Millikan, RC. Mitochondrial DNA G10398A polymorphism and invasive breast cancer in African-American
women. Cancer Res, 65(17), 8028-33, 2005
Parl, FF. Glutathione S-transferase genotypes and cancer risk. Cancer Lett, 221(2), 123-9, 2005
Dawling, S, Hachey, DL, Roodi, N, Parl, FF. In vitro model of mammary estrogen metabolism: structural and kinetic differences
between catechol estrogens 2- and 4-hydroxyestradiol. Chem Res Toxicol, 17(9), 1258-64, 2004
Roodi, Nady, Dupont, William D, Moore, Jason H, Parl, Fritz F. Association of homozygous wild-type glutathione S-transferase M1 genotype with increased breast cancer risk. Cancer Res, 64(4), 1233-6, 2004
Kallianpur, Asha R, Hall, Lynn D, Yadav, Meeta, Christman, Brian W, Dittus, Robert S, Haines, Jonathan L, Parl, Fritz F, Summar, Marshall L. Increased prevalence of the HFE C282Y hemochromatosis allele in women with breast cancer. Cancer Epidemiol Biomarkers Prev, 13(2), 205-12, 2004
Parl, F F. Multiple mechanisms of estrogen receptor gene repression contribute to ER-negative breast cancer. Pharmacogenomics J, 3(5), 251-3, 2003
Hachey, David L, Dawling, Sheila, Roodi, Nady, Parl, Fritz F. Sequential action of phase I and II enzymes cytochrome p450 1B1 and glutathione S-transferase P1 in mammary estrogen metabolism. Cancer Res, 63(23), 8492-9, 2003
Dawling, Sheila, Roodi, Nady, Parl, Fritz F. Methoxyestrogens exert feedback inhibition on cytochrome P450 1A1 and 1B1. Cancer Res, 63(12), 3127-32, 2003
Dawling, S, Roodi, N, Mernaugh, R L, Wang, X, Parl, F F. Catechol-O-methyltransferase (COMT)-mediated metabolism of catechol estrogens: comparison of wild-type and variant COMT isoforms. Cancer Res, 61(18), 6716-22, 2001
Carter, B A, Page, D L, Schuyler, P, Parl, F F, Simpson, J F, Jensen, R A, Dupont, W D. No elevation in long-term breast carcinoma risk for women with fibroadenomas that contain atypical hyperplasia. Cancer, 92(1), 30-6, 2001
Ritchie, M D, Hahn, L W, Roodi, N, Bailey, L R, Dupont, W D, Parl, F F, Moore, J H. Multifactor-dimensionality reduction reveals high-order interactions among estrogen-metabolism genes in sporadic breast cancer. Am J Hum Genet, 69(1), 138-47, 2001
Garte, S, Gaspari, L, Alexandrie, A K, Ambrosone, C, Autrup, H, Autrup, J L, Baranova, H, Bathum, L, Benhamou, S, Boffetta, P, Bouchardy, C, Breskvar, K, Brockmoller, J, Cascorbi, I, Clapper, M L, Coutelle, C, Daly, A, Dell'Omo, M, Dolzan, V, Dresler, C M, Fryer, A, Haugen, A, Hein, D W, Hildesheim, A, Hirvonen, A, Hsieh, L L, Ingelman-Sundberg, M, Kalina, I, Kang, D, Kihara, M, Kiyohara, C, Kremers, P, Lazarus, P, Le Marchand, L, Lechner, M C, van Lieshout, E M, London, S, Manni, J J, Maugard, C M, Morita, S, Nazar-Stewart, V, Noda, K, Oda, Y, Parl, F F, Pastorelli, R, Persson, I, Peters, W H, Rannug, A, Rebbeck, T, Risch, A, Roelandt, L, Romkes, M, Ryberg, D, Salagovic, J, Schoket, B, Seidegard, J, Shields, P G, Sim, E, Sinnet, D, Strange, R C, St??cker, I, Sugimura, H, To-Figueras, J, Vineis, P, Yu, M C, Taioli, E. Metabolic gene polymorphism frequencies in control populations. Cancer Epidemiol Biomarkers Prev, 10(12), 1239-48, 2001
Nass, S J, Herman, J G, Gabrielson, E, Iversen, P W, Parl, F F, Davidson, N E, Graff, J R. Aberrant methylation of the estrogen receptor and E-cadherin 5' CpG islands increases with malignant progression in human breast cancer. Cancer Res, 60(16), 4346-8, 2000
Hanna, I H, Dawling, S, Roodi, N, Guengerich, F P, Parl, F F. Cytochrome P450 1B1 (CYP1B1) pharmacogenetics: association of polymorphisms with functional differences in estrogen hydroxylation activity. Cancer Res, 60(13), 3440-4, 2000
Parl FF. Estrogens, Estrogen Receptor and Breast Cancer. IOS Press, Amsterdam, Oxford, Tokyo, 2000
Dupont, W D, Page, D L, Parl, F F, Plummer, W D, Schuyler, P A, Kasami, M, Jensen, R A. Estrogen replacement therapy in women with a history of proliferative breast disease. Cancer, 85(6), 1277-83, 1999
Lapidus, R. G., Nass, S. J., Butash, K. A., Parl, F. F.,
Weitzman, S.
A., Graff, J. G., Herman, J. G., Davidson, N. E. Mapping
of ER
gene CpG island methylation by methylation specific PCR. Cancer Res , 58, 2515-2519, 1998
Bailey, L R, Roodi, N, Dupont, W D, Parl, F F. Association of cytochrome P450 1B1 (CYP1B1) polymorphism with steroid receptor status in breast cancer. Cancer Res, 58(22), 5038-41, 1998
Bailey, L R, Roodi, N, Verrier, C S, Yee, C J, Dupont, W D, Parl, F F. Breast cancer and CYPIA1, GSTM1, and GSTT1 polymorphisms: evidence of a lack of association in Caucasians and African Americans. Cancer Res, 58(1), 65-70, 1998
Verrier, C S, Roodi, N, Yee, C J, Bailey, L R, Jensen, R A, Bustin, M, Parl, F F. High-mobility group (HMG) protein HMG-1 and TATA-binding protein-associated factor TAF(II)30 affect estrogen receptor-mediated transcriptional activation. Mol Endocrinol, 11(8), 1009-19, 1997
Benge, H, Bodor, G S, Younger, W A, Parl, F F. Impact of managed care on the economics of laboratory operation in an academic medical center. Arch Pathol Lab Med, 121(7), 689-94, 1997
Lapidus, R G, Ferguson, A T, Ottaviano, Y L, Parl, F F, Smith, H S, Weitzman, S A, Baylin, S B, Issa, J P, Davidson, N E. Methylation of estrogen and progesterone receptor gene 5' CpG islands correlates with lack of estrogen and progesterone receptor gene expression in breast tumors. Clin Cancer Res, 2(5), 805-10, 1996
Yaich LE, Roodi N, Bailey LR, Verrier CS, Yee CJ, Cavener DR, Parl FF. Analysis of estrogen receptor gene, transcript and protein in ER-positive and -negative breast cancer cell lines. Endocrine-Related Cancer, 2, 293-309, 1995
Roodi, N, Bailey, L R, Kao, W Y, Verrier, C S, Yee, C J, Dupont, W D, Parl, F F. Estrogen receptor gene analysis in estrogen receptor-positive and receptor-negative primary breast cancer. J Natl Cancer Inst, 87(6), 446-51, 1995
Ottaviano YL, Issa JP, Parl FF, Smith HS, Baylin SB, Davidson NE. Methylation of the estrogen receptor gene CpG island marks loss of estrogen receptor expression in human breast cancer cells. Cancer Res, 54, 2552-2555, 1994
Caleffi, M, Teague, M W, Jensen, R A, Vnencak-Jones, C L, Dupont, W D, Parl, F F. p53 gene mutations and steroid receptor status in breast cancer. Clinicopathologic correlations and prognostic assessment. Cancer, 73(8), 2147-56, 1994
Yee, C J, Roodi, N, Verrier, C S, Parl, F F. Microsatellite instability and loss of heterozygosity in breast cancer. Cancer Res, 54(7), 1641-4, 1994
Dupont, W D, Page, D L, Parl, F F, Vnencak-Jones, C L, Plummer, W D, Rados, M S, Schuyler, P A. Long-term risk of breast cancer in women with fibroadenoma. N Engl J Med, 331(1), 10-5, 1994
Dupont, W D, Parl, F F, Hartmann, W H, Brinton, L A, Winfield, A C, Worrell, J A, Schuyler, P A, Plummer, W D. Breast cancer risk associated with proliferative breast disease and atypical hyperplasia. Cancer, 71(4), 1258-65, 1993
Yaich, L, Dupont, W D, Cavener, D R, Parl, F F. Analysis of the PvuII restriction fragment-length polymorphism and exon structure of the estrogen receptor gene in breast cancer and peripheral blood. Cancer Res, 52(1), 77-83, 1992
Foster, B D, Cavener, D R, Parl, F F. Binding analysis of the estrogen receptor to its specific DNA target site in human breast cancer. Cancer Res, 51(13), 3405-10, 1991
Dupont, W D, Page, D L, Rogers, L W, Parl, F F. Influence of exogenous estrogens, proliferative breast disease, and other variables on breast cancer risk. Cancer, 63(5), 948-57, 1989
Parl, F F, Cavener, D R, Dupont, W D. Genomic DNA analysis of the estrogen receptor gene in breast cancer. Breast Cancer Res Treat, 14(1), 57-64, 1989
Parl, F F, Posey, Y F. Discrepancies of the biochemical and immunohistochemical estrogen receptor assays in breast cancer. Hum Pathol, 19(8), 960-6, 1988
Parl, F F, Schonbaum, C P, Cox, D L, Cavener, D R. Detection of estrogen receptor mRNA in human uterus. Mol Cell Endocrinol, 52(3), 235-42, 1987
Parl, F F. Estrogen receptor determination in human breast cancer. Prog Clin Pathol, 9, 155-72, 1984
Parl, F F, Schmidt, B P, Dupont, W D, Wagner, R K. Prognostic significance of estrogen receptor status in breast cancer in relation to tumor stage, axillary node metastasis, and histopathologic grading. Cancer, 54(10), 2237-42, 1984
Parl, F F, Wetherall, N T, Halter, S, Schuffman, S, Mitchell, W M. Comparison of histochemical and biochemical assays for estrogen receptor in human breast cancer cell lines. Cancer Res, 44(1), 415-21, 1984
Parl, F F, Richardson, L D. The histologic and biologic spectrum of tubular carcinoma of the breast. Hum Pathol, 14(8), 694-8, 1983
Parl, F F, Dupont, W D. A retrospective cohort study of Histologic risk factors in breast cancer patients. Cancer, 50(11), 2410-6, 1982
Parl, F F, Wagner, R K. The histopathological evaluation of human breast cancers in correlation with estrogen receptor values. Cancer, 46(2), 362-7, 1980
Entenmann, A H, Parl, F F, Jungblut, P W. Studies on the involvement of lysosomes in estrogen action, II. Seasonal variation in the sedimentation patterns of endometrial lysosomes from prepuberal pigs. Hoppe Seylers Z Physiol Chem, 360(11), 1651-5, 1979
