Gehrie, E, Neff, AT, Ciombor, KK, Harris, N, Seegmiller, AC, Young, PP. Profound piperacillin-mediated drug-induced immune hemolysis in a patient with cystic fibrosis. Transfusion, 2011
Young, PP, Cotton, BA, Goodnough, LT. Massive transfusion protocols for patients with substantial hemorrhage. Transfus Med Rev, 25(4), 293-303, 2011
Li, B, Pozzi, A, Young, PP. TNFalpha accelerates monocyte to endothelial transdifferentiation in tumors by the induction of integrin alpha5 expression and adhesion to fibronectin. Mol Cancer Res, 9(6), 702-11, 2011
Alfaro, MP, Saraswati, S, Young, PP. Molecular mediators of mesenchymal stem cell biology. Vitam Horm, 87, 39-59, 2011
Garcia, CB, Shaffer, CM, Alfaro, MP, Smith, AL, Sun, J, Zhao, Z, Young, PP, Vansaun, MN, Eid, JE. Reprogramming of mesenchymal stem cells by the synovial sarcoma-associated oncogene SYT-SSX2. Oncogene, 2011
O''Leary, MF, Szklarski, P, Klein, TM, Young, PP. Hemolysis of red blood cells after cell washing with different automated technologies: clinical implications in a neonatal cardiac surgery population. Transfusion, 51(5), 955-60, 2011
Saraswati, S, Alfaro, MP, Thorne, CA, Atkinson, J, Lee, E, Young, PP. Pyrvinium, a potent small molecule Wnt inhibitor, promotes wound repair and post-MI cardiac remodeling. PLoS One, 5(11), e15521, 2010
Alfaro, MP, Vincent, A, Saraswati, S, Thorne, CA, Hong, CC, Lee, E, Young, PP. sFRP2 suppression of bone morphogenic protein (BMP) and Wnt signaling mediates mesenchymal stem cell (MSC) self-renewal promoting engraftment and myocardial repair. J Biol Chem, 285(46), 35645-53, 2010
Cotton, BA, Dossett, LA, Haut, ER, Shafi, S, Nunez, TC, Au, BK, Zaydfudim, V, Johnston, M, Arbogast, P, Young, PP. Multicenter validation of a simplified score to predict massive transfusion in trauma. J Trauma, 69 Suppl 1, S33-9, 2010
Pyle, AL, Young, PP. Atheromas feel the pressure: biomechanical stress and atherosclerosis. Am J Pathol, 177(1), 4-9, 2010
Cates, JM, Friedman, DB, Seeley, EH, Dupont, WD, Schwartz, HS, Holt, GE, Caprioli, RM, Young, PP. Proteomic analysis of osteogenic sarcoma: association of tumour necrosis factor with poor prognosis. Int J Exp Pathol, 2010
Li, B, Vincent, A, Cates, J, Brantley-Sieders, DM, Polk, DB, Young, PP. Low levels of tumor necrosis factor alpha increase tumor growth by inducing an endothelial phenotype of monocytes recruited to the tumor site. Cancer Res, 69(1), 338-48, 2009
Cotton, BA, Au, BK, Nunez, TC, Gunter, OL, Robertson, AM, Young, PP. Predefined massive transfusion protocols are associated with a reduction in organ failure and postinjury complications. J Trauma, 66(1), 41-8; discussion 48-9, 2009
Barnes, SL, Young, PP, Miga, MI. A novel model-gel-tissue assay analysis for comparing tumor elastic properties to collagen content. Biomech Model Mechanobiol, 8(4), 337-43, 2009
Au, BK, Dutton, WD, Zaydfudim, V, Nunez, TC, Young, PP, Cotton, BA. Hyperkalemia following massive transfusion in trauma. J Surg Res, 157(2), 284-9, 2009
Pyle AL, Li B, Maupin AB, Guzman RJ, Crimmins DL, Olson S, Atkinson JB and Young PP. . Biomechanical stress induces novel arterial intima-enriched genes: implications for vascular adaptation to stress. . Cardiovasc Pathol, in press, 2009
Li B, Vincent A, Cates J, Brantley-Sieders, D, Polk DB, Young PP. Low levels of TNF increase tumor growth by inducing an endothelial phenotype of monocytes recruited to the tumor site. Cancer Res, in press, 2009
Pyle, AL, Atkinson, JB, Pozzi, A, Reese, J, Eckes, B, Davidson, JM, Crimmins, DL, Young, PP. Regulation of the atheroma-enriched protein, SPRR3, in vascular smooth muscle cells through cyclic strain is dependent on integrin alpha1beta1/collagen interaction. Am J Pathol, 173(5), 1577-88, 2008
Devin JK, Vaughan DE, Blevins LS, Chen Q, Covington J, Verity DK, and Young PP. Low-dose growth hormone administration mobilizes endothelial progenitor cells in healthy adults. Growth Hormone and IGF Res., 9, 983-92, 2008
Pyle, AL, Li, B, Maupin, AB, Guzman, RJ, Crimmins, DL, Olson, S, Atkinson, JB, Young, PP. Biomechanical stress induces novel arterial intima-enriched genes: implications for vascular adaptation to stress. Cardiovasc Pathol, 19(2), e13-20, 2008
Gunter, OL, Au, BK, Isbell, JM, Mowery, NT, Young, PP, Cotton, BA. Optimizing outcomes in damage control resuscitation: identifying blood product ratios associated with improved survival. J Trauma, 65(3), 527-34, 2008
Cotton, BA, Gunter, OL, Isbell, J, Au, BK, Robertson, AM, Morris, JA, St Jacques, P, Young, PP. Damage control hematology: the impact of a trauma exsanguination protocol on survival and blood product utilization. J Trauma, 64(5), 1177-82; discussion 1182-3, 2008
Alfaro, MP, Pagni, M, Vincent, A, Atkinson, J, Hill, MF, Cates, J, Davidson, JM, Rottman, J, Lee, E, Young, PP. The Wnt modulator sFRP2 enhances mesenchymal stem cell engraftment, granulation tissue formation and myocardial repair. Proc Natl Acad Sci U S A, 105(47), 18366-71, 2008
Alfaro MP, Pagni M, Vincent A, Atkinson J, Hill MF, Cates J, Davidson JM, Rottman J, Lee E, and Young PP. . A Wnt modulator sFRP2 enhances mesenchymal stem cell engraftment, granulation tissue formation and myocardial repair. . Proc. Natl. Acad. Sci. , USA, Track 2, in press, 2008
Santoro, SA, Mosse, CA, Young, PP. The MD/PhD pathway to a career in laboratory medicine. Clin Lab Med, 27(2), 425-34; abstract ix, 2007
Ryzhov, S, Solenkova, NV, Goldstein, AE, Lamparter, M, Fleenor, T, Young, PP, Greelish, JP, Byrne, JG, Vaughan, DE, Biaggioni, I, Hatzopoulos, AK, Feoktistov, I. Adenosine Receptor Mediated Adhesion of Endothelial Progenitors to Cardiac Microvascular Endothelial Cells. Circ Res, 2007
Young, PP, Vaughan, DE, Hatzopoulos, AK. Biologic properties of endothelial progenitor cells and their potential for cell therapy. Prog Cardiovasc Dis, 49(6), 421-9, 2007
Sharpe, EE, Teleron, AA, Li, B, Price, J, Sands, MS, Alford, K, Young, PP. The origin and in vivo significance of murine and human culture-expanded endothelial
progenitor cells. Am J Pathol, 168(5), 1710-21, 2006
Li, B, Sharpe, EE, Maupin, AB, Teleron, AA, Pyle, AL, Carmeliet, P, Young, PP. VEGF and PlGF promote adult vasculogenesis by enhancing EPC recruitment and
vessel formation at the site of tumor neovascularization. FASEB J, 20(9), 1495-7, 2006
Young, PP, Modur, V, Teleron, AA, Ladenson, JH. Enrichment of genes in the aortic intima that are associated with stratified
epithelium: implications of underlying biomechanical and barrier properties of the arterial intima. Circulation, 111(18), 2382-90, 2005
Teleron, Amylynn A, Carlson, Brian, Young, Pampee P. Blood donor white blood cell reduction filters as a source of human peripheral
blood-derived endothelial progenitor cells. Transfusion, 45(1), 21-5, 2005
Young, PP, Uzieblo, A, Trulock, E, Lublin, DM, Goodnough, LT. Autoantibody formation after alloimmunization: are blood transfusions a risk factor for autoimmune hemolytic anemia. Transfusion, 44(1), 67-72, 2004
Alcorn, JL, Islam, KN, Young, PP, Mendelson, CR. Glucocorticoid inhibition of SP-A gene expression in lung type II cells is mediated via the TTF-1-binding element. Am J Physiol Lung Cell Mol Physiol, 286(4), L767-76, 2004
Young, Pampee P, Fantz, Corinne R, Sands, Mark S. VEGF disrupts the neonatal blood-brain barrier and increases life span after
non-ablative BMT in a murine model of congenital neurodegeneration caused by a lysosomal enzyme deficiency. Exp Neurol, 188(1), 104-14, 2004
Young, Pampee P, Vogler, Carole, Alex Hofling, A, Sands, Mark S, . Biodistribution and efficacy of donor t lymphocytes in a murine model of lysosomal storage disease.. Mol Ther, 7, 52-61, 2003
Young, Pampee P, Hofling, A Alex, Sands, Mark S, . VEGF increases engraftment of bone marrow-derived endothelial progenitor cells (EPCs) into vasculature of newborn murine recipients.. Proc Natl Acad Sci U S A, 99, 11951-6, 2002
Young, P P, Goodnough, L T, Westervelt, P, Diersio, J F, . Immune hemolysis involving non-ABO/RhD alloantibodies following hematopoietic stem cell transplantation.. Bone Marrow Transplant, 27, 1305-10, 2001
Young, P P, Buller, R S, Storch, G A, . Evaluation of a commercial DNA enzyme immunoassay for detection of enterovirus reverse transcription-PCR products amplified from cerebrospinal fluid specimens.. J Clin Microbiol, 38, 4260-1, 2000
Mendelson, C R, Gao, E, Li, J, Young, P P, Michael, L F, Alcorn, J L, . Regulation of expression of surfactant protein-A.. Biochim Biophys Acta, 1408, 132-49, 1998
Mendelson, C R, Gao, E, Young, P P, Michael, L F, Alcorn, J L, . Transcriptional regulation of the surfactant protein-A gene in fetal lung.. Chest, 111, 96S-104S, 1997
Young, P P, Mendelson, C R, . A GT box element is essential for basal and cyclic adenosine 3',5'-monophosphate regulation of the human surfactant protein A2 gene in alveolar type II cells: evidence for the binding of lung nuclear factors distinct from Sp1.. Mol Endocrinol, 11, 1082-93, 1997
Young, PP, Mendelson, CR. A CRE-like element plays an essential role in cAMP regulation of human SP-A2 gene in alveolar type II cells. Am J Physiol, 271(2 Pt 1), L287-99, 1996
