Department of Pathology, Microbiology, and Immunology

Ling Geng, M.D.

Research Associate Professor

Dept. of Pathology, Microbiology and Immunology

Contact Information

Office Location:

MCN C-2121 (Zutter Lab)

Phone: 615-343-0534
E-mail: ling.geng@vanderbilt.edu

Campus Mail address:

Pathology, Microbiology and Immunology-3rd Fl

MCN C-3321 (2561)

US Mailing address:

Vanderbilt University School of Medicine
Dept of Pathology, Microbiology and Immunology-3rd Fl
MCN C-3321

Nashville, TN 37232-2561

Education

M.D., Suzhou Medical College

Publications

Thotala, DK, Geng, L, Dickey, AK, Hallahan, DE, Yazlovitskaya, EM. A new class of molecular targeted radioprotectors: GSK-3beta inhibitors. Int J Radiat Oncol Biol Phys, 76(2), 557-65, 2010
Perez, CA, Fu, A, Onishko, H, Hallahan, DE, Geng, L. Radiation induces an antitumour immune response to mouse melanoma. Int J Radiat Biol, 85(12), 1126-36, 2009
Geng, L, Rachakonda, G, Morr??, DJ, Morr??, DM, Crooks, PA, Sonar, VN, Roti, JL, Rogers, BE, Greco, S, Ye, F, Salleng, KJ, Sasi, S, Freeman, ML, Sekhar, KR. Indolyl-quinuclidinols inhibit ENOX activity and endothelial cell morphogenesis while enhancing radiation-mediated control of tumor vasculature. FASEB J, 23(9), 2986-95, 2009
Linkous, A, Geng, L, Lyshchik, A, Hallahan, DE, Yazlovitskaya, EM. Cytosolic phospholipase A2: targeting cancer through the tumor vasculature. Clin Cancer Res, 15(5), 1635-44, 2009
Cuneo, KC, Geng, L, Fu, A, Orton, D, Hallahan, DE, Chakravarthy, AB. SU11248 (sunitinib) sensitizes pancreatic cancer to the cytotoxic effects of ionizing radiation. Int J Radiat Oncol Biol Phys, 71(3), 873-9, 2008
Tu, T, Thotala, D, Geng, L, Hallahan, DE, Willey, CD. Bone marrow X kinase-mediated signal transduction in irradiated vascular endothelium. Cancer Res, 68(8), 2861-9, 2008
Han, Z, Fu, A, Wang, H, Diaz, R, Geng, L, Onishko, H, Hallahan, DE. Noninvasive assessment of cancer response to therapy. Nat Med, 14(3), 343-9, 2008
Cuneo, KC, Tu, T, Geng, L, Fu, A, Hallahan, DE, Willey, CD. HIV protease inhibitors enhance the efficacy of irradiation. Cancer Res, 67(10), 4886-93, 2007
Cuneo, KC, Fu, A, Osusky, K, Huamani, J, Hallahan, DE, Geng, L. Histone deacetylase inhibitor NVP-LAQ824 sensitizes human nonsmall cell lung cancer to the cytotoxic effects of ionizing radiation. Anticancer Drugs, 18(7), 793-800, 2007
Geng, L, Cuneo, KC, Cooper, MK, Wang, H, Sekhar, K, Fu, A, Hallahan, DE. Hedgehog signaling in the murine melanoma microenvironment. Angiogenesis, 10(4), 259-67, 2007
Cuneo, KC, Fu, A, Osusky, KL, Geng, L. Effects of vascular endothelial growth factor receptor inhibitor SU5416 and prostacyclin on murine lung metastasis. Anticancer Drugs, 18(3), 349-55, 2007
Albert, JM, Cao, C, Kim, KW, Willey, CD, Geng, L, Xiao, D, Wang, H, Sandler, A, Johnson, DH, Colevas, AD, Low, J, Rothenberg, ML, Lu, B. Inhibition of poly(ADP-ribose) polymerase enhances cell death and improves tumor growth delay in irradiated lung cancer models. Clin Cancer Res, 13(10), 3033-42, 2007
Cao, C, Albert, JM, Geng, L, Ivy, PS, Sandler, A, Johnson, DH, Lu, B. Vascular endothelial growth factor tyrosine kinase inhibitor AZD2171 and fractionated radiotherapy in mouse models of lung cancer. Cancer Res, 66(23), 11409-15, 2006
Geng, L, Cuneo, KC, Fu, A, Tu, T, Atadja, PW, Hallahan, DE. Histone deacetylase (HDAC) inhibitor LBH589 increases duration of gamma-H2AX foci and confines HDAC4 to the cytoplasm in irradiated non-small cell lung cancer. Cancer Res, 66(23), 11298-304, 2006
Kim, DW, Huamani, J, Niermann, KJ, Lee, H, Geng, L, Leavitt, LL, Baheza, RA, Jones, CC, Tumkur, S, Yankeelov, TE, Fleischer, AC, Hallahan, DE. Noninvasive assessment of tumor vasculature response to radiation-mediated, vasculature-targeted therapy using quantified power Doppler sonography: implications for improvement of therapy schedules. J Ultrasound Med, 25(12), 1507-17, 2006
Cao, C, Subhawong, T, Albert, JM, Kim, KW, Geng, L, Sekhar, KR, Gi, YJ, Lu, B. Inhibition of mammalian target of rapamycin or apoptotic pathway induces autophagy and radiosensitizes PTEN null prostate cancer cells. Cancer Res, 66(20), 10040-7, 2006
Albert, JM, Cao, C, Geng, L, Leavitt, L, Hallahan, DE, Lu, B. Integrin alpha v beta 3 antagonist Cilengitide enhances efficacy of radiotherapy in endothelial cell and non-small-cell lung cancer models. Int J Radiat Oncol Biol Phys, 65(5), 1536-43, 2006
Cuneo, KC, Geng, L, Tan, J, Brousal, J, Shinohara, ET, Osusky, K, Fu, A, Shyr, Y, Wu, H, Hallahan, DE. SRC family kinase inhibitor SU6656 enhances antiangiogenic effect of irradiation. Int J Radiat Oncol Biol Phys, 64(4), 1197-203, 2006
Cao, C, Shinohara, ET, Subhawong, TK, Geng, L, Woon Kim, K, Albert, JM, Hallahan, DE, Lu, B. Radiosensitization of lung cancer by nutlin, an inhibitor of murine double minute 2. Mol Cancer Ther, 5(2), 411-7, 2006
Tan, J, Geng, L, Yazlovitskaya, EM, Hallahan, DE. Protein kinase B/Akt-dependent phosphorylation of glycogen synthase kinase-3beta in irradiated vascular endothelium. Cancer Res, 66(4), 2320-7, 2006