Department of Pathology, Microbiology, and Immunology
Host-Pathogens Interactions Division Faculty
Name |
Specialty |
||
|---|---|---|---|
|
Molecular biology of HIV-1 replication |
|||
|
|
|||
|
The use of functional genomic and epigenetic approaches to understand gene regulation. |
|||
|
|
|||
|
Post-translational modifications that regulate signal transduction in the mammalian immune system. |
|||
|
Common mechanisms by which growth factors mediate and influence organ formation during embryogenesis. |
|||
|
How signal transduction and mechanisms of gene transcription control regulate immunity and immune-related disease mechanisms. |
|||
|
Evolutionary and functional genomics of animal microbiomes |
|||
|
Bacteria-host interactions, bacterial toxins, Helicobacter pylori, and gastric cancer |
|||
|
Virology, immunology, vaccine research |
|||
|
Functional cure of HIV-1 infection and human APOBEC3 proteins |
|||
|
Coronavirus Replication, Cell Biology and Experimental Evolution; Emerging Infections; Synthetic Biology |
|||
|
Mechanisms of anti-HIV drug failure and cellular drug transporters; host defense factors in HIV infection; and HIV compartmentalization and evolution in genital tract |
|||
|
Chikungunya virus and reovirus cell entry, replication, and pathogenesis; reovirus-based vaccine vectors; oncolytic reovirus therapeutics |
|||
|
The role of infectious agents in idiopathic pulmonary diseases with an emphasis on CD4+ T cell immunology, pathogenic mycobacteria and granulomatous inflammation |
|||
|
|
|||
|
Adult Infectious Diseases |
|||
|
|
|||
|
Growth factor and cytokine receptors on T lymphocytes |
|||
|
Characterization of molecular and biochemical events during differentiation of African trypanosomes. Development of trypanocidal drugs. Fostering and supporting a diverse research and healthcare workforce. |
|||
|
|
|||
|
|
|||
|
Understanding how antigen processing and presentation regulate T lymphocyte function in health and disease: How is T cell development and survival regulated? What do T cells recognize? How are these molecules processed for proper recognition? How does antigen processing and presentation lead to the induction of the proper immune response? |
|||
|
Viral immunology; HIV vaccine research |
|||
|
Kendall, Peggy |
B lymphocyte tolerance in Type 1 diabetes |
||
|
Tuberculosis vaccine development, staphylococcal vaccine development, antibiotic resistance mechanisms |
|||
|
Bacterial protein toxins, structural biology |
|||
|
Functional genomics and systems biology analysis of the immune response and gene expression |
|||
|
Transplantation and autoimmunity |
|||
|
Type 1 diabetes and transplantation biology; regulation of auto- and allo-reactive lymphocytes |
|||
|
Interactions between cells of the mucosal immune system and intestinal epithelial cells, and how these interactions modify the effector T cell responses, with special interest on the impact related to inflammatory bowel diseases and infections of the intestines. |
|||
|
The role of the adaptive immune system in lung granulomatous inflammation. |
|||
|
Amphibian Immune Defenses, Antimicrobial Peptide Defenses, Developmental and Comparative Immunology, Chytridiomycosis and Global Amphibian Declines |
|||
|
Molecular Genetics of the Pathogen-Host Interaction, Mechanism of Mucosal Immunity |
|||
|
Genetic analysis of growth control and development |
|||
|
Combined molecular/cellular analysis of the adaptive and innate immune systems |
|||
|
|
|||
|
|
|||
|
Bacteriology and Innate Immunity |
|||
|
Structural Biology of ion channels, virulence factors, host-pathogen relationship, and cytoskeletal regulation |
|||
|
Mechanism of CNS demyelination |
|||
|
Mechanisms that regulate immune tolerance and why they fail in autoimmune disorders such as type 1 diabetes |
|||
|
Immune regulation, MHC class I molecules, glycolipid-reactive T cells, mucosal immunity, autoimmunity |
|||
|
Pediatric infectious diseases |
|||
|
Mucosal immunology and inflammation; macrophases; arginine metabolism, nitric oxide, and polyamines; host-pathogen interactions; Helicobacter pylori; colitis. |
|||
|
Effects of lipid excess on the immune system and immunological functions, especially in the context of obesity and metabolic diseases |
|||
|
Integrin-mediated cell adhesion in development, cancer, innate immunity and vascular biology. |
|||
