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Vanderbilt Pathology Laboratory Services

Test Directory



ARGATROBAN ASSAY (ARG)

Department: Coagulation
Test Synonym(s): ARG, ANTI-lla ASSAY
CPT Codes: 85130
Methodology: Chromogenic
Reference Range: Not Defined Plasma Argatroban levels of 0.40 to 1.50 ug/mL generally correspond to a 1.5 to 2.5-fold increase in the PTT above baseline.
Tube Type: Light Blue top (Sodium Citrate) - 2.7 mL
Specimen: Citrated plasma - platelet poor. This sample requires double centrifugation if sending a plasma aliquot
Alternate Specimen: None

Pediatric Requirements: Peds: 2.7 mL, Neonates: 1.8 mL
Volume: 1.0 mL Plasma
Minimum Volume: 1.0 mL Plasma
Temperature: Room temperature or double centrifuge and send as a frozen aliquot if sample will not be received into lab within 1 hour. This sample requires double centrifugation if sending a plasma aliquot.
Stability: Room temperature: 1 hour
Reasons for Rejection: Clotted sample, incorrectly filled tube, sample sent as whole blood >1 hours old, markedly hemolyzed sample
Days Performed: Monday-Friday
Times Performed: 8 AM - 4 PM. After hours testing must be approved by the Director or Pathology resident on call
TAT: 1 day
Significance: Assay result is dependent on patient's level of Antithrombin III
Special Instructions: Indwelling line should be flushed with saline and 5.0 mL of blood discarded before collecting samples for coagulation assays. Tube must be full and not clotted. Deliver to lab immediately. Samples received from an outside lab must be aliquoted and frozen. Samples aliquoted for shipping must be double centrifuged prior to freezing. Grossly hemolyzed, icteric or lipemic samples may be rejected.


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