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Vanderbilt Pathology Laboratory Services

Test Directory



RESPIRATORY VIRAL PANEL (RVP)

Department: Molecular Infectious Disease
Test Synonym(s): RESPIRATORY VIRUS PCR, RVP
CPT Codes: 87633
Methodology: PCR - Polymerase Chain Reaction
Reference Range: Not detected
Tube Type: Swab in Universal Transport Medium, Sterile container
Specimen: Nasal washing, nasal secretions, nasopharyngeal swabs
Alternate Specimen: Bronchoalveolar lavage (BAL) and tracheal aspirates are accepted as nonpreferred specimen types, and results will be reported with a disclaimer. Sputum specimens are not acceptable and will be rejected. Other specimen types require Medical Director approval; contact the lab prior to specimen collection for approval and collection instructions
Pediatric Requirements: Nasal washing, nasal secretions, nasopharyngeal swabs
Volume: 0.5 mL
Minimum Volume: 0.2 mL
Temperature: Refrigerated: 3 days; -80C: longer than 3 days
Stability: Refrigerated: 3 days; -80C: longer than 3 days
Reasons for Rejection: Alternative specimen sent without Medical Director approval
Days Performed: Monday - Friday
Times Performed: Once per day
TAT: 1 - 3 days
Significance: Acute respiratory virus infections are among the most common causes of human disease. These viruses are responsible for a spectrum of illness that includes upper and lower respiratory infection, otitis media, parotitis, and encephalitis. Infants, the elderly, and individuals with compromised cardiac, pulmonary, or immune systems are at greatest risk of serious complications. Common respiratory viruses are nearly indistinguishable on clinical grounds. Prompt detection and identification of these pathogens may contribute importantly to initiation of antiviral therapy, avoiding unnecessary antimicrobial therapy, preventing nosocomial spread, decreasing duration of hospital stays, and reducing patient management costs. PCR assays offer increased sensitivity over traditional methods (e.g., viral antigen detection, culture, and immunofluorescence methods) for the laboratory diagnosis of acute respiratory viral illness. The GenMark eSensor Respiratory Viral Panel amplifies, detects, and differentiates 17 respiratory viruses in multiplex format. These include influenza A (seasonal H1, 2009 pandemic H1N1, H3), influenza B, RSV A, RSV B, parainfluenza types 1 - 4, human metapneumovirus, human rhinovirus, adenovirus (B, C, E), and coronavirus (229E, NL63, HKU1, OC43).
Special Instructions: Transport on wet ice.
Click here to print the Molecular Diagnostics requisition.

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