PROTEIN S ACTIVITY and TOTAL PROTEIN S ANTIGEN, FREE PROTEIN S ANTIGEN (SAA)
: SAA, Protein S
: Protein S Activity, Protein S Antigen Free, Protein S Antigen Total.
: 85306 x2
: ACTIVITY - Clotting
ANTIGEN - Immunoturbidimetric
: ACTIVITY: 55 - 123%
ANTIGEN: 60 - 130%
: One 2.7mL Light blue top - 3.2% Sodium Citrate
: Citrated platelet poor plasma - Requires double centrifugation if sending a plasma aliquot. Aliquot(s) must be frozen if not received by lab within two hours of collection.
: Pediatric: One 2.7mL Light blue top - 3.2% Sodium Citrate. Neonatal: One 1.8mL Light blue top - 3.2% Sodium Citrate.
: 1.0 mL Plasma
: 1.0 mL Plasma
: Room Temperature for Light blue top tube, must be received within two hours of draw. Plasma aliquot(s) must be frozen if not received by lab within two hours of collection.
: Room temperature: 2 hours, Frozen: -70 C for one month
Reasons for Rejection
: Clotted sample, incorrectly filled tubes, incorrect tube type, grossly hemolyzed sample, grossly lipemic sample, grossly icteric sample, whole blood >2.0 hours old
: Monday - Friday
: 1 - 3 days
: ACTIVITY TEST:Presence of a lupus anticoagulant or anti cardiolipin antibodies in the patient plasma may interfere with this assay. In this circumstance, measuring free protein S antigen levels may be more useful. Direct thrombin inhibitors may interfere with this assay.
ANTIGEN TEST: Rheumatoid factor levels >70 IU/mL may lead to an underestimation for the free Protein S antigen level.
: Deliver to lab immediately. Tubes must be filled to indicator line and not clotted. Indwelling lines should be flushed with saline only and 5 mL of blood should be discarded prior to collecting samples for coagulation studies. If sending plasma aliquots, DOUBLE CENTRIFUGE plasma samples to produce platelet poor plasma. Samples received from an outside lab must be aliquoted and frozen. Grossly hemlyzed, icteric or lipemic samples may be rejected. Ordering physician name and telephone contact information MUST accompany the sample and request.
Vanderbilt Esoteric Coagulation Laboratory: 615 875-5633
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