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Vanderbilt Pathology Laboratory Services

Test Directory



BARTONELLA COXIELLA DETECTION (BCD)

Department: Molecular Infectious Disease
Test Synonym(s): BCD
CPT Codes: 87471, 87798
Methodology: PCR - Polymerase Chain Reaction
Reference Range: Not Detected
Tube Type: Tissue: sterile container or paraffin block
Specimen: Heart Valve Tissue
Alternate Specimen: Other samples with Medical Directory approval
Volume: 1.0 ml
Minimum Volume: 0.5 ml
Temperature: FFPE: Room temperature; Fresh Tissue: -80C
Stability: FFPE: Room temperature; Fresh tissue: -80C
Reasons for Rejection: Alternative specimen sent without Medical Director approval
Days Performed: Monday
Times Performed: Batched (once per week)
TAT: 2 - 15 days
Significance: BK virus (BKV) is commonly first encountered in childhood, resulting in asymptomatic or mild (fever and URI) illness. BKV is a significant cause of morbidity and mortality in immunocompromised patients, such as solid-organ or bone marrow transplant recipients. Reactivated BKV infection can manifest as non-hemorrhagic or hemorrhagic cystitis and ureteric stenosis. Additionally, renal transplant recipients can develop polyomavirus-associated nephropathy (PVAN) with progressive loss of kidney function and high rates of allograft rejection. Measurement of BKV loads in urine and blood using quantitative PCR may aid the diagnosis and management of BKV-induced nephropathy.
Special Instructions: Analytical measurement range (Urine): 50 - 500,000 cpy/mL. Analytical measurement range (Blood): 500 - 5,000,000 cpy/mL.

Click here to print the Molecular Diagnostics requisition.

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