HYPERCOAGULABLE STATE PANEL (HYC)
: HYC, Thrombosis Panel, Thrombophilia Panel
: PT/INR, PTT, DRVV & Confirm, Hexagonal Phase PTT, APA Abs (IgG,M,A), B2GPI Abs (IgG,M), FVL, AT3 activity, Protein C & S activity, Free Protein S ag, G20210A gene mutation analysis. Reflex to FVL mutation analysis & AT, Protein C & S ags if needed.
: 85610, 85730, 85612, 85613, 85597, 86147 x 3, 86146 x 2, 85307, 83896 x 2, 83891, 83903, 83892 x 2, 83912, 85300, 85303, 85306, 85301, 85302, 85306, 85305, 83896 x 2, 83912, 83903, 83891, 83892 x 2, 80500
: Various: clotting, chromogenic and direct detection of mutation R506Q and/or G20210A
: See individual assays
: Four 2.7mL Light blue top - 3.2% Sodium Citrate. One 2.7 mL lavender top tube - EDTA
: Citrated platelet poor plasma - Requires double centrifugation if sending a plasma aliquot. Aliquot(s) must be frozen if not received by lab within two hours of collection.**if sending plasma aliquots, will also require one tube of the centrifuged cells to be sent.
: Pediatric: Four 2.7mL Light blue top - 3.2% Sodium Citrate. One 2.7 mL lavender top tube - EDTA One 2.7 mL lavender top tube - EDTA Neonatal: Three 2.7 mL Light blue top - 3.2% Sodium Citrate.
: 4.0 mL Plasma
: 4.0 mL Plasma
: Room Temperature for Light blue top tube, must be received within 4 hours of draw. Plasma aliquot(s) must be frozen if not received by lab within 4 hours of collection.
: Room temperature: 4 hours, Frozen: -70 C for one month
Reasons for Rejection
: Clotted sample, incorrectly filled tubes, incorrect tube type, grossly hemolyzed sample, grossly lipemic sample, grossly icteric sample, whole blood >4.0 hours old
: Monday - Friday
: 1 - 3 days
: Direct Thrombin and both Direct and Indirect anti-Xa inhibitors may interfere with these assays. Coumadin will interfere with these assays. Heparins will interfere with these assays.
: Deliver to lab immediately. Tubes must be filled to indicator line and not clotted. Indwelling lines should be flushed with saline only and 5 mL of blood should be discarded prior to collecting samples for coagulation studies. If sending plasma aliquots, DOUBLE CENTRIFUGE plasma samples to produce platelet poor plasma. Samples received from an outside lab must be aliquoted and frozen. Grossly hemlyzed, icteric or lipemic samples may be rejected. Ordering physician name and telephone contact information MUST accompany the sample and request.
Vanderbilt Esoteric Coagulation Laboratory: 615 875-5633
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