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Vanderbilt Pathology Laboratory Services

Test Directory



KRAS (KRS)

Department: Molecular Diagnostics
Test Synonym(s): KRS
CPT Codes: 81275
Methodology: Allele specific detection for mutations G12C, G12D, G12S, G13D, G12A, G12R, G12V, G13C by PCR and evaluated by capillary electrophoresis
Specimen: Paraffin embedded tissue; block, 5-10 unstained slides or 5 curls (NOTE: slides and curls 10ým thick with accomanying before and after cut H & E slides)
Alternate Specimen: None
Temperature: Room temperature
Stability: Paraffin block - indefinitely
Reasons for Rejection: Decalcification (paraffin embedded tissue). Client will be notified by Molecular Diagnostics Lab if specimen is rejected.
Days Performed: Once a week - variable days
Times Performed: Batched
TAT: 7 - 10 days
Significance: DNA analysis for 8 common mutations in Codons 12 and 13
Special Instructions: Call the Molecular Diagnostics Laboratory at 615-343-8121 if additional assistance is needed regarding specimen requirements or submission.

Click here to print the Molecular Diagnostics requisition.>Click here to print the Molecular Diagnostics requisition.






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