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Vanderbilt Pathology Laboratory Services

Test Directory



PLASMINOGEN ACTIVITY (PLS)

Department: Coagulation
Test Synonym(s): PLS
CPT Codes: 85420
Methodology: Clotting
Reference Range: 70 - 115%
Tube Type: Light blue top (Sodium Citrate)
Specimen: Citrated plasma - platelet poor. This sample requires double centrifugation if sending a plasma aliquot

Alternate Specimen: None
Pediatric Requirements: Peds - 2.7 mL Neonates - 1.8 mL
Volume: 1.0 mL plasma
Minimum Volume: 1.0 mL plasma
Temperature: Room temperature, or send as a frozen plasma aliquot if sample will not be received into the lab within 4 hours
Stability: Room temperature: 4 hours
Reasons for Rejection: Clotted sample, incorrectly filled tube, sample sent as whole blood > 4 hours old.
Days Performed: Monday - Friday
Times Performed: 8:00 a.m. - 4:00 p.m.
TAT: 1 day
Significance: Presence of Aprotinin in the sample will result in an under estimation of the plasminogen level.
Special Instructions: Indwelling line should be flushed with saline and 5.0 mL of blood discarded before collecting samples for coagulation assays. Tube must be full and not clotted. Deliver to lab immediately. Samples received from an outside lab must be aliquoted and frozen. Samples aliquoted for shipping must be double centrifuged prior to freezing. Grossly hemolyzed, icteric or lipemic samples may be rejected.


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