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Vanderbilt Pathology Laboratory Services

Test Directory



PREKALLIKREIN SCREEN (PRE)

Department: Coagulation
Test Synonym(s): PRE
CPT Codes: 85292
Methodology: Clotting
Reference Range: Screen reveals no evidence of HMWK or prekallikrein deficiency.
Tube Type: Light blue top (Sodium Citrate) - 2 tubes required
Specimen: Citrated plasma - platelet poor. This sample requires double centrifugation if sending a plasma aliquot

Alternate Specimen: None
Pediatric Requirements: Peds - 2.7 mL (2 tubes required) Neonates - 2.7 mL
Volume: Plasma from 2 (2.7 mL) light blue (Sodium Citrate) tubes
Minimum Volume: Plasma from 2 (2.7 mL) light blue (Sodium Citrate) tubes
Temperature: Refrigerated plasma aliquot or send as a frozen plasma aliquot if sample will not be received into the lab within 1 hour.
Stability: Refrigerated plasma aliquot: 4 hours
Reasons for Rejection: Clotted sample, incorrectly filled tube, sample sent as whole blood > 1 hours old.
Days Performed: Monday - Friday
Times Performed: 8:00 a.m. - 4:00 p.m. After hours testing must be approved by the Director or Pathology resident on call.
TAT: 1 day
Special Instructions: Indwelling line should be flushed with saline and 5.0 mL of blood discarded before collecting samples for coagulation assays. Tube must be full and not clotted. Deliver to lab immediately. Samples received from an outside lab must be aliquoted and frozen. Samples aliquoted for shipping must be double centrifuged prior to freezing. Grossly hemolyzed, icteric or lipemic samples may be rejected.


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