ALDOSTERONE / RENIN RATIO (ART)
: Estoeric Chemistry
: ART, ARR
: Aldosterone, Plasma Renin Activity, Aldosterone/Plasma Renin Activity Ratio
: 82088, 84244
: Aldosterone: Supine (<23.6 ng/dL), Upright (<35.3 ng/dL); Plasma Renin Activity: Normal Salt Intake - Upright (0.7 - 3.3 ng/mL/hr), Supine (0.3 - 1.7 ng/mL/hr), Aldosterone/Plasma Renin Activity Ratio - less than or equal to 30
: ALD and RN: Lavender top (EDTA) tube
: PlasmaClick here to view Aldosterone/Renin Recommendations.
: ALD: Serum - Red top (no gel)
: 2 microtainers - ALD: 1.0 mL plasma (EDTA); RN: 1.0 mL Plasma (EDTA)
: ALD: 4 mL; RN: 4 mL
: Ald: 2.0 mL Adults, 1.0 mL Children; RN: 2.0 mL Adults, 1.0 mL Children
: Room Temperature
: ALD: Room temperature -- 1 week, 4 C -- 2 months, -20 C -- 1 month; RN: Room Temperature -- 6 hours; Frozen -- 1 month (Do not refridgerate or store on ice)
Reasons for Rejection
: ALD: QNS, delay in processing; RN: Collection and/or Transport to lab on ice or refrigerated; Specimen not frozen within 6 hours; QNS
: Tuesday and Thursday
: 8:00 a.m.
: 5 days
: The Endocrine Society suggests that an Aldosterone/Plasma Renin Activity Ratio >30 may be associated with hyperaldosteronism. Due to assay and biological variability, interpret this ratio in the context of the aldosterone result and interfering medications. Please see recommendations and appended table for more information on assay interferences and retesting. Funder, JW, et al. JCEM. 2008; 93: 3266-3281Click here to view Aldosterone/Renin Interference Table.Click here to view Aldosterone/Renin Recommendations.
: Specimens should be collected midmorning after the patient has been up for at least 2 hours and seated for 5 - 15 minutes. Collect specimens at room temperature (not on ice) and delivery immediately to the laboratory. Avoid stasis, hemolysis, and fist clenching during collection.
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