Vanderbilt Pathology Laboratory Services
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C REACTIVE PROTEIN BLOOD (CRP)
Department: ChemistryTest Synonym(s): CRP, Inflammatory CRP
CPT Codes: 86140
Methodology: Particle Enhanced Turbidimetric
Reference Range: <10.0 mg/L CRP
Tube Type: Light green PST (Lithium Heparin with gel) tube - 4.5 mL, EDTA
Specimen: Plasma
Alternate Specimen: Red top tube - 5 mL
Pediatric Requirements: Draw 2 microtainers
Volume: 1 mL plasma
Minimum Volume: 0.5 mL plasma
Temperature: Separate within one hour and store at 2-8ºC until delivery
Stability: < 3 days at 4ºC; 6 months at -20ºC
Reasons for Rejection: Hemolysis, improper collection
Days Performed: Daily
Times Performed: Continuous
TAT: STAT: 1 hour; ROUTINE: 2 hours after receiving in lab
Significance: CRP is an acute phase reactant and a non-specific inflammatory marker widely used to assess inflammatory processes. It is elevated in systemic inflammation, bacterial infections, surgery and severe trauma. CRP values should be interpreted in the context of the clinical history.
Reference: Tietz Textbook of Clinical Chemistry. 5th edition. Edited by CA Burtis, ER Ashwood. Philadelphia, WB Saunders Company, 2012
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