ELECTROPHORESIS AND IMMUNOFIXATION FOR MONOCLONAL IMMUNOGLOBULIN (BLOOD) (SPEP)
: SPEP, Protein Electrophoresis, SI, SPE
: Includes both electrophoresis densitometric scan and immunofixation of Kappa and Lambda.
: No monoclonal
: Red top (no anti-coagulant)
: 5 mL whole blood
: 1 mL whole blood
: Refrigerate, spin and separate
Reasons for Rejection
: Drawn in any anticoagulant
: Monday - Friday
: Usually 48 hours
: Principle clinical indications for ordering include suspected multiple myeloma, Waldenstrom's macroglobulinemia, amyloidosis, peripheral neuropathy, unexplained renal insufficiency, Nephrotic syndrome, hypogammaglobulinemia in adults and autonomic insufficiency.
: Must order total protein (blood). If none ordered, total protein will be ordered and charged. Screening test for identification of monoclonal gammopathies in serum. If monoclonal protein is detected, follow-up identification will be performed and charged additionally.
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